[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579145":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":31,"centralContacts":40,"locations":50,"responsibleParty":67,"collaborators":31,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":31,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":31,"enrollmentInfo":79,"targetDuration":31,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":53,"whyStopped":31,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University Ghent","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Conventional connective tissue graft","ACTIVE_COMPARATOR","Connective tissue graft immediately inserted in buccal pouch",[13],"Procedure: Conventional connective tissue graft after immediate implant placement",{"label":15,"type":16,"description":17,"interventionNames":18},"Scarf connective tissue graft","EXPERIMENTAL","Connective tissue graft immediately fixed onto the buccal mucosa.",[19],"Procedure: Scarf connective tissue graft after immediate implant placement",{"label":21,"type":16,"description":22,"interventionNames":23},"Dual zone concept","Bone material condensed up to the buccal soft tissue margin.",[24],"Procedure: Dual zone concept after immediate implant placement",[26,32,36],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"PROCEDURE","Conventional connective tissue graft after immediate implant placement","A pouch is made in the buccal mucosa extending 3 mm below the buccal bone crest. Thereupon, a free gingival graft is harvested from the palatal mucosa and de-epithelialized. The CTG is brought into the pouch and fixed with two single sutures onto the buccal mucosa. A healing abutment is installed, which is replaced by a provisional implant crown 2 days later. Sutures are removed 1 week after the surgery.",[9],null,{"type":27,"name":33,"description":34,"armGroupLabels":35,"otherNames":31},"Scarf connective tissue graft after immediate implant placement","No pouch is made in the recipient site. A free gingival graft is harvested from the palatal mucosa and de-epithelialized. The small CTG is fixed at the transmucosal aspect onto the buccal mucosa. A healing abutment is installed, which is replaced by a provisional implant crown 2 days later. Sutures are removed 1 week after the surgery.",[15],{"type":27,"name":37,"description":38,"armGroupLabels":39,"otherNames":31},"Dual zone concept after immediate implant placement","DBBM is applied and condensed up to the level of the buccal soft tissue margin. A healing abutment is installed, which is replaced by a provisional implant crown 2 days later. Usually, sutures are not needed in this group, unless minimal papilla opening was required to extract the tooth. In that case, sutures will be removed after 1 week.",[21],[41,46],{"name":42,"role":43,"phone":44,"phoneExt":31,"email":45},"Véronique Christiaens, PhD","CONTACT","09\u002F332 40 17","vchristi.christiaens@UGent.be",{"name":47,"role":43,"phone":48,"phoneExt":31,"email":49},"Jan Cosyn, PhD","09\u002F332 40 18","jan.cosyn@UGent.be",[51],{"facility":52,"status":53,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Ghent University Hospital","RECRUITING","Ghent","East Flanders","9000","Belgium","BE",{"type":60,"coordinates":61},"Point",[62,63],3.71667,51.05,{"lat":63,"lon":62},[66],{"name":42,"role":43,"phone":44,"phoneExt":31,"email":45},{"type":68,"investigatorFullName":31,"investigatorTitle":31,"investigatorAffiliation":31,"oldNameTitle":31,"oldOrganization":31},"SPONSOR","100579145","comparison-of-three-transmucosal-augmentation-techniques-in-immediate-implant-placement-100579145",false,"NCT06820489","Comparison of Three Transmucosal Augmentation Techniques in Immediate Implant Placement","A Three-arm Randomized Controlled Trial Comparing Transmucosal Augmentation Techniques in Immediate Implant Placement","Inclusion Criteria:\n\n* At least 20 years old\n* Good oral hygiene defined as full-mouth plaque score ≤ 25%\n* Presence of an incisor, cuspid or premolar in the maxilla that needs to be extracted for any reason with at least one neighboring tooth present\n* At least 3 mm bone available at the apical or palatal aspect of the alveolus as assessed on CBCT to ensure primary implant stability\n* Intact buccal bone wall (type I) or limited buccal bone dehiscence (type IIa or IIb) at the time of extraction\n* Written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy\n* Systemic diseases\n* Smoking; suppuration\n* \\> 1 mm gingival asymmetry between the failing and contralateral tooth\n* Untreated periodontal disease\n* Untreated caries lesions.",true,"ALL","20 Years",{"count":80,"type":81},54,"ESTIMATED","INTERVENTIONAL",[84],"NA","Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT). Prior to surgery, a small- field low-dose cone beam computed tomography (CBCT) is taken to verify the integrity of the facial bone wall and an adequate amount of apical and palatal bone availability for implant anchorage. 54 patients will be randomly assigned to either conventional connective tissue graft (C-CTG), scarf tissue graft (S-CTG) or dual zonde conept (DZ). Sealed envelopes are prepared for that purpose, of which 18 are internally labeled as C-CTG, 18 as S-CTG and 18 as DZ. Following IIP, a sealed envelope will be opened to reveal the treatment concept.\n\nSuccessful regeneration (primary outcome) is achieved when the combination of socket grafting and transmucosal augmentation (C-CTG or S-CTG or DZ) would be able to counteract any buccal soft tissue loss at level -1 mm. It is assessed on the basis of superimposed CBCTs taken pre-operatively and at one-year follow-up. Secondary outcomes include: horizontal buccal bone loss, vertical buccal bone loss, increase in buccal soft tissue thickness, patient-reported outcomes, plaque, bleeding on probing, probing depth, marginal bone loss, change in buccal soft tissue profile, midfacial soft tissue level, mesial and distal papilla level, Pink Esthetic Score.",[87],"Bone Resorption",[89,90,91],"Dental Implant, Single-Tooth","Immediate","Connective tissue graft","2026-01-07",{"date":94,"type":95},"2026-01-09","ACTUAL",{"date":97,"type":95},"2025-04-01",{"date":99,"type":81},"2031-11-01",{"name":5,"class":6},1]