[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628927":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":36,"collaborators":7,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":7,"eligibilityCriteria":46,"healthyVolunteers":42,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":7,"studyType":53,"phases":7,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Brno University Hospital","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Hana Harazim, MD, PhD","CONTACT","+420777146704","hana.harazim@gmail.com",[15],{"facility":16,"status":17,"city":18,"state":7,"zip":19,"country":20,"countryCode":7,"cosmosGeoPoint":21,"geoPoint":26,"contacts":27},"University Hospital Brno","RECRUITING","Brno","61300","Czechia",{"type":22,"coordinates":23},"Point",[24,25],16.60796,49.19522,{"lat":25,"lon":24},[28,33],{"name":29,"role":11,"phone":30,"phoneExt":31,"email":32},"Daniel Diabelko, MD","727845778","00420","diabelko.daniel@fnbrno.cz",{"name":10,"role":11,"phone":34,"phoneExt":31,"email":35},"777146704","harazim.hana@fnbrno.cz",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Petr Štourač, MD","prof. Petr Štourač, MD, PhD, MBA, LLM, FESAIC","100628927","comparison-of-transcutaneous-and-blood-co-measurement-in-critically-ill-children-100628927",false,"NCT07468006","Comparison of Transcutaneous and Blood CO₂ Measurement in Critically Ill Children","Comparison of Transcutaneous Carbon Dioxide Monitoring With Arterialized or Arterial Blood Gas Analysis in PICU","Inclusion Criteria:\n\n* Age 1-18 years\n* Diagnosis of respiratory insufficiency or impaired peripheral perfusion\n* Expected need for more than one arterialized capillary or arterial blood gas sample\n* Admission to PICU\n\nExclusion Criteria:\n\n* Repeated failure of sensor adhesion\n* Hypothermia \\\u003C 35 °C\n* Time difference \\> ±5 minutes between tPCO₂ and blood sampling\n* Large tPCO₂ variability (\\> ±1 kPa) in 15 minutes preceding blood sampling\n* Non-physiological tPCO₂ values incompatible with life","ALL","1 Year","18 Years",{"count":51,"type":52},20,"ESTIMATED","OBSERVATIONAL","Transcutaneous capnometry (tPCO₂) is a non-invasive method for continuous monitoring of ventilation status. In pediatric intensive care patients, it may reduce the need for repeated arterial or arterialized blood sampling. However, the accuracy of tPCO₂ may be influenced by factors such as peripheral perfusion, skin temperature, and vasopressor therapy. This prospective observational study compares transcutaneous carbon dioxide measurements with arterialized or arterial blood gas PaCO₂ values in children with respiratory insufficiency, including a subgroup receiving vasopressor support.",[56],"Respiratory Insufficiency in Children",[58,59,60,61,62],"pediatric intensive care","transcutaneous capnometry","carbon dioxide monitoring","blood gas analysis","vasopressors","2026-03-10",{"date":65,"type":66},"2026-03-12","ACTUAL",{"date":68,"type":66},"2026-01-01",{"date":70,"type":52},"2028-01-31",{"name":5,"class":6},1]