[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100484598":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":35,"centralContacts":47,"locations":58,"responsibleParty":75,"collaborators":35,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":81,"sex":86,"minAge":87,"maxAge":35,"enrollmentInfo":88,"targetDuration":35,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":35,"overallStatus":61,"whyStopped":35,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Laval University","OTHER",[8,14,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Nonin oximeter with a 90% SpO2 target","EXPERIMENTAL","During this periods , oxygen will be administered in an manual titration with the FreeO2 device (fixed flow mode) to reach 90% of SpO2.",[13],"Device: Manual oxygen titration with Nonin oximeter (SpO2 target 90%)",{"label":15,"type":10,"description":16,"interventionNames":17},"Philips oximeter with a 90% SpO2 target","During this periods, oxygen will be administered in a manual titration with the FreeO2 device (fixed flow mode), to reach 90% of SpO2.",[18],"Device: Manual Oxygen titration with Philips oximeter (SpO2 target 90%)",{"label":20,"type":10,"description":21,"interventionNames":22},"Nonin oximeter with a 94% SpO2 target","During this periods , oxygen will be administered in a manual titration with the FreeO2 device (fixed flow mode) to reach 94% of SpO2.",[23],"Device: Manual oxygen titration with Nonin oximeter (SpO2 target 94%)",{"label":25,"type":10,"description":26,"interventionNames":27},"Philips oximeter with a 94% SpO2 target","During this periods, oxygen will be administered in a manual titration with the FreeO2 device (fixed flow mode), to reach 94% of SpO2.",[28],"Device: Manual Oxygen titration with Philips oximeter (SpO2 target 94%)",[30,36,40,44],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DEVICE","Manual Oxygen titration with Philips oximeter (SpO2 target 90%)","Oxygen titration with FreeO2 device (fixed flow mode) to reach the SpO2 target (set at 90%) with Philips oximeter",[15],null,{"type":31,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"Manual oxygen titration with Nonin oximeter (SpO2 target 90%)","Oxygen titration with FreeO2 device (fixed flow mode) to reach the SpO2 target (set at 90%) with Nonin oximeter",[9],{"type":31,"name":41,"description":42,"armGroupLabels":43,"otherNames":35},"Manual Oxygen titration with Philips oximeter (SpO2 target 94%)","Oxygen titration with FreeO2 device (fixed flow mode) to reach the SpO2 target (set at 94%) with Philips oximeter",[25],{"type":31,"name":45,"description":42,"armGroupLabels":46,"otherNames":35},"Manual oxygen titration with Nonin oximeter (SpO2 target 94%)",[20],[48,54],{"name":49,"role":50,"phone":51,"phoneExt":52,"email":53},"Francois Lellouche","CONTACT","418656-8711","3572","francois.lellouche@criucpq.ulaval.ca",{"name":55,"role":50,"phone":51,"phoneExt":56,"email":57},"Pierre Alexandre Bouchard","2712","pierre-alexandre.bouchard@criucpq.ulaval.ca",[59],{"facility":60,"status":61,"city":62,"state":63,"zip":64,"country":65,"countryCode":66,"cosmosGeoPoint":67,"geoPoint":72,"contacts":73},"Institut Universitaire de Cardiologie et de Pneumologie de Québec","RECRUITING","Québec","Quebec","G1V4G5","Canada","CA",{"type":68,"coordinates":69},"Point",[70,71],-71.21454,46.81228,{"lat":71,"lon":70},[74],{"name":49,"role":50,"phone":35,"phoneExt":35,"email":53},{"type":76,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":35,"oldOrganization":35},"PRINCIPAL_INVESTIGATOR","François Lellouche","Principal investigator","100484598","comparison-of-two-oxygenation-targets-with-two-different-oximeters---impact-on-oxygen-flow-rates-and-oxygenation-100484598",false,"NCT05590130","Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation","Oxygap pong","Inclusion Criteria:\n\n* ≥ 18 years of age\n* Patients admitted to postoperative cardiac surgery intensive care unit\n* Presence of an arterial catheter Specific for the extubate patient\n* Ongoing on conventional oxygen therapy at moderate flow (up to a maximum of 5L\u002Fmin) with SpO2 between 88 and 100% with the usual oximeter and nasal cannula.\n* SpO2 \\\u003C 92% ambient air Specific for the intubate patient FiO2 \\\u003C= 0.60 with SpO2 between 88 and 100% with usual oximeter SpO2 \\\u003C 92% with FiO2 0.21\n\nExclusion Criteria:\n\n* No SpO2 signal with oximeter in use\n* False nails or nail polish\n* Methemoglobinemia \\>0.015 on last available arterial gas\n* Patient in isolation (multi-resistant bacteria, C-Difficile, SARS-CoV-2 ...) Specific for the extubate patient\n* Expected to use another respiratory support within one hour of inclusion (NIV or nasal high flow oxygen) Planned extubation within one hour of inclusion","ALL","18 Years",{"count":89,"type":90},40,"ESTIMATED","INTERVENTIONAL",[93],"NA","The investigators recently evaluated 4 different oximeters among the most commonly used with arterial catheter in place and compared SpO2 with SaO2 obtained on arterial gas. Correlations between SaO2 and SpO2 were poor for all oximeters, as previously known, and SpO2-SaO2 bias were different between oximeters. Some oximeters (Masimo, Nellcor) had lower biases but they detected less well hypoxemia. Some oximeters underestimated SaO2 (Nonin) but detected very well hypoxemia, and some overestimated SaO2 (Philips). The investigators concluded that oximeters provide different informations to clinicians, and oxygenation targets should take into account for these differences.\n\nThe assumption is that the SpO2 target AND oximeter used will both have an impact on oxygen flows and that these effects will add up. With a high SpO2 target, oxygen flows will be significantly greater and with the Nonin oximeter, the required flows will be greater than with the Philips oximeter.\n\nNB: the results obtained were in a population with light skin pigmentation (96% of the patients were Fitzpatrick 1-2, reflecting the local hospitalized population).",[96,97],"Oxygen Toxicity","Respiratory Failure","2025-08-27",{"date":100,"type":101},"2025-09-04","ACTUAL",{"date":103,"type":101},"2022-11-16",{"date":105,"type":90},"2027-06",{"name":5,"class":6},1]