[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590488":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":26,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":26,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":64,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":76,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"İstanbul Yeni Yüzyıl Üniversitesi","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"SAP + SIP Block Group","EXPERIMENTAL","Participants in this arm will receive a combination of ultrasound-guided serratus anterior plane (SAP) block and serratus-intercostal interfascial plane (SIP) block. The SAP block will be performed using 30 mL of 0.25% bupivacaine, and the SIP block will use 10 mL of 0.25% bupivacaine. Both blocks will be administered after surgery but before emergence from anesthesia.",[13],"Procedure: Ultrasound-guided serratus anterior plane block and serratus-intercostal interfascial plane block with bupivacaine",{"label":15,"type":16,"description":17,"interventionNames":18},"Local Wound Infiltration Group","ACTIVE_COMPARATOR","Participants in this arm will receive local wound infiltration (LWI) consisting of 40 mL of 0.25% bupivacaine. The infiltration will be applied to the surgical and drain sites after surgery.",[19],"Procedure: Local wound infiltration with bupivacaine",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ultrasound-guided serratus anterior plane block and serratus-intercostal interfascial plane block with bupivacaine","Participants will receive an ultrasound-guided serratus anterior plane (SAP) block using 30 mL of 0.25% bupivacaine combined with a serratus-intercostal interfascial plane (SIP) block using 10 mL of 0.25% bupivacaine. Both blocks will be administered after surgery but before emergence from anesthesia. This combination targets multiple interfascial planes to enhance postoperative analgesia in patients undergoing minimally invasive cardiac surgery (MICS).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Local wound infiltration with bupivacaine","Participants will receive local wound infiltration with 40 mL of 0.25% bupivacaine applied to the surgical and drain sites following surgery. This approach represents a standard method for managing postoperative pain in MICS patients and serves as the active comparator.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Selcuk Alver, MD","CONTACT","+905435424234","alverselcuk@gmail.com",[38],{"facility":39,"status":40,"city":41,"state":26,"zip":26,"country":42,"countryCode":26,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Kolan International Hospital","RECRUITING","Istanbul","Turkey (Türkiye)",{"type":44,"coordinates":45},"Point",[46,47],28.94966,41.01384,{"lat":47,"lon":46},[50],{"name":51,"role":34,"phone":52,"phoneExt":26,"email":53},"Ali Şefik Köprülü, MD","+905322677226","askoprulu@yahoo.com",{"type":55,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100590488","comparison-of-ultrasound-guided-serratus-combination-plane-blocks-and-local-wound-infiltration-for-postoperative-analgesia-management-in-minimally-invasive-cardiac-surgery-mics-100590488",false,"NCT06968065","Comparison of Ultrasound-Guided Serratus Combination Plane Blocks and Local Wound Infiltration for Postoperative Analgesia Management in Minimally Invasive Cardiac Surgery (MICS)","Inclusion Criteria:\n\n* Age 18-75 years\n* Undergoing MICS with left-sided 4th-5th intercostal incision\n* ASA I-III\n* Informed consent provided\n\nExclusion Criteria:\n\n* Coagulopathy or on anticoagulants\n\n  * Allergy to local anesthetics or opioids\n  * Local infection at block site\n  * Pregnancy or lactation\n  * Bilateral thoracic incisions\n  * Refusal to participate","ALL","18 Years","75 Years",{"count":66,"type":67},60,"ESTIMATED","INTERVENTIONAL",[70],"NA","This randomized, prospective, single-blinded study aims to compare the efficacy of ultrasound-guided serratus anterior plane (SAP) block combined with serratus-intercostal interfascial plane (SIP) block versus local wound infiltration (LWI) for postoperative analgesia in patients undergoing minimally invasive cardiac surgery (MICS). The primary outcome is total perioperative and postoperative opioid consumption. Secondary outcomes include postoperative pain scores (NRS), opioid-related side effects, block-related complications, and ICU stay duration.",[73,74,75],"Pain, Postoperative","Heart Surgery","Analgesia",[73,77,75,78,79],"Heart Surgery, Minimally Invasive","Bupivacaine","Opioid-Related Disorders","2025-05-05",{"date":82,"type":83},"2025-05-13","ACTUAL",{"date":85,"type":83},"2024-10-17",{"date":87,"type":67},"2025-06",{"name":5,"class":6},1]