[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599881":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":57,"collaborators":24,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":24,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":24,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":24,"overallStatus":81,"whyStopped":24,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group I zinc oxide with Neem","EXPERIMENTAL","Neem and zinc oxide powder have been improved as a theraputic agents with high antibacterial, antioxidant, and enzyme-inhibiting properties against microorganisms resistant to antibiotics.Neem contains many chemically diverse and structurally complex phytochemicals, such as limonoids, flavonoids, phenols, catechins, gallic acid,polyphenols, and nimbins which contribute to their different pharmacological activities.",[13],"Other: Group I zinc oxide Neem",{"label":15,"type":10,"description":16,"interventionNames":17},"Group II zinc oxide -eugenol","zinc oxide eugenol is a mixture of zinc oxide (powder) and eugenol (liquid). Zinc oxide and eugenol (ZOE) paste is a standard in dentistry among the pastes used in the pulp therapy of primary teeth.",[18],"Other: Group II zinc oxide eugenol",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Group I zinc oxide Neem","preperation: 1\\\\ A standardized access cavity procedure will be performed using a large sterile round end bur in a high-speed handpiece with copious irrigation, a sharp spoon excavator will remove coronal pulpal tissues then will remove radicular pulp by barbed broach then will be used K files for chemo mechanical preparation (size 15,20,25) with saline (2%) irrigation to remove necrotic pulp tissues then all the canals will be dried using paper points. 2\\\\ After complete excavation of all pulp tissue, saline irrigation is done then the canals will be obturated zinc-oxide with Neem ( Zinc oxide powder(Prime Dental Pvt. Ltd.Thane, Maharashtra, India) and 100% Neem oil with mixing ratio of 1:3 will be mixed on a glass slab with a stainless- steel spatula) and then the rest of the pulp chamber will be filled with Zinconol. (reinforced zinc oxide eugenol)3\\\\ Tooth will be restored with stainless steel crown.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Group II zinc oxide eugenol","preperation: 1\\\\ A standardized access cavity procedure will be performed using a large sterile round end bur in a high-speed handpiece with copious irrigation, a sharp spoon excavator will remove coronal pulpal tissues then will remove radicular pulp by barbed broach then will be used K files for chemo mechanical preparation (size 15,20,25) with saline (2%) irrigation to remove necrotic pulp tissues then all the canals will be dried using paper points 2\\\\ After complete removed of coronal and radicular pulp zinc oxide eugenol will be manipulated in the ratio of 3:1 (powder: liquid) to obtain semisolid mix.This mix will be placed in the canals. Gentle condensation of the mix will be done in the pulp chamber with a moistened cotton pellet, followed by the application of Zinconol.3\\\\ Tooth will be restored with stainless steel crown.",[15],[30],{"name":31,"affiliation":5,"role":32},"Adel Elbardissy, Prof Doctor","STUDY_DIRECTOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Tasneem Ali Osman Ali, Master degree","CONTACT","+201151360396","tasneem.ali@dentistry.cu.edu.eg",[40],{"facility":41,"status":24,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Cairo University Faculty of Dentistry","Cairo","El-manial","3387722","Egypt","EG",{"type":48,"coordinates":49},"Point",[50,51],31.24967,30.06263,{"lat":51,"lon":50},[54],{"name":41,"role":36,"phone":55,"phoneExt":24,"email":56},"0020223642705","rec@dentistry.cu.edu.eg",{"type":58,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Tasneem Ali Osman Ali","Principle investigator","100599881","comparison-of-zoe-vs-zon-in-primary-mandibular-molars-pulpectomy-of-5-7-year-olds-100599881",false,"NCT07090252","Comparison of ZOE vs ZON in Primary Mandibular Molars Pulpectomy of 5-7-Year-Olds","Clinical and Radiographic Evaluation of Zinc Oxide-eugenol and Zinc Oxide With Neem as Obturating Materials in Primary Mandibular Molars Pulpectomy for 5-7 Year-Old Children: A Randomized Clinical Trail","Inclusion Criteria:\n\n1. Children aged 5-7 years with infected primary molars.\n2. Deep carious lesion.\n3. History of spontaneous pain\n4. Parent written informed consent.\n\nExclusion Criteria:\n\n1. Medically compromised children\n2. Children with a history of allergic reaction to the components of the tested material\n3. Children who had non restorable teeth\n4. Teeth with less than two third of root length\n5. Extensive internal or external root resorption\n6. Unable to attend follow-up visits",true,"ALL","5 Years","7 Years",{"count":73,"type":74},24,"ESTIMATED","INTERVENTIONAL",[77],"NA","The goal of this clinical trial is to evaluation of Zinc oxide-eugenol compared to Zinc oxide with Neem as obturating materials in primary mandibular molars pulpectomy for 5-7 Year-Old Children.The main question(s)it aim to answer : Could the clinical and radiographic success of a mixture of zinc oxide with Neem oil be comparable with Zinc oxide-eugenol paste in pulpectomy of primary mandibular molars?",[80],"Carious Primary Molars","NOT_YET_RECRUITING","2025-07-29",{"date":84,"type":85},"2025-08-01","ACTUAL",{"date":87,"type":74},"2025-09-01",{"date":89,"type":74},"2026-11-01",{"name":5,"class":6},1]