[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609646":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":55,"collaborators":58,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":63,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":26,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":26,"overallStatus":83,"whyStopped":26,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Lahore University of Biological and Applied Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Complete Decongestive Therapy (CDT) and Routine Physical Therapy","ACTIVE_COMPARATOR","Group A: Complete Decongestive Therapy (CDT) and Routine Physical Therapy:\n\nManual Lymphatic Drainage (MLD)\n\n* Duration: 30 minutes\u002Fsession\n* Frequency: 5 days\u002Fweek\n* Technique: Performed by a certified lymphedema therapist\n* Areas: Neck, axilla, trunk, and affected limb\n* Total treatment time: 8 weeks 2. Compression Bandaging\n* Type: Multi-layer short-stretch bandaging\n* Application: After MLD in each session\n* Worn Duration: 22-23 hours\u002Fday\n* Reapplied Daily: Yes 3. Skin Care\n* Duration: 10 minutes\u002Fsession\n* Components:\n\n  * Inspection of skin\n  * Use of pH-neutral moisturizers\n  * Infection prevention education 4. Exercise Therapy (Routine Physiotherapy)\n* Type: Gentle, active ROM and resistance exercises (e.g., shoulder mobility, grip strengthening)\n* Duration: 20 minutes\u002Fsession\n* Progression: Gradually increase intensity over 8 weeks",[13],"Other: Complete Decongestive therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B: Non-pneumatic compression device (NPCD) and Routine Physiotherapy (RPT)","EXPERIMENTAL","Subjects will be taught how to apply the device themselves, including placement, duration of use, and turning it on\u002Foff. All subjects will be instructed to wear the device for up to 40 minutes per day and to continue their usual activity during use. Routine Physical Therapy:\n\n* Type: Gentle, active ROM and resistance exercises (e.g., shoulder mobility, grip strengthening)\n* Duration: 20 minutes\u002Fsession\n* Progression: Gradually increase intensity over 8 weeks",[19],"Device: Non Pneumatic compression device",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Non Pneumatic compression device","Non-Pneumatic Compression Device (NPCD) is a wearable, portable system providing gradient sequential compression through shape-memory alloy actuators instead of air pressure. Frequency: 5 sessions per week for 8 weeks.\n\nIntensity: Moderate, rhythmic static and dynamic compression applied distally to proximally, allowing safe lymphatic drainage.\n\nTime: 40 minutes per session, once daily.",[15],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Complete Decongestive therapy","Complete Decongestive Therapy (CDT), is the gold-standard, non-invasive treatment for lymphedema. It combines manual lymphatic drainage (MLD), compression bandaging, exercise therapy, and skin care to reduce limb swelling and improve lymphatic flow.\n\nFrequency: 5 sessions per week for 8 weeks. Intensity: Gentle manual drainage with multilayer compression Time: 60 minutes per session. Type: Therapist-guided manual and compression therapy followed by self-management.\n\nCDT aims to decongest the limb, prevent fibrosis and infection, and enhance mobility and quality of life in post-mastectomy lymphedema patients.",[9],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Sahar Fatima, Ph.D","CONTACT","+923371683000","fatima.sahar0212@gmail.com",[38],{"facility":39,"status":26,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Cancer Care Hospital","Lahore","Punjab Province","74600","Pakistan","PK",{"type":46,"coordinates":47},"Point",[48,49],74.35071,31.558,{"lat":49,"lon":48},[52],{"name":53,"role":34,"phone":54,"phoneExt":26,"email":36},"sahar fatima","03371683000",{"type":56,"investigatorFullName":57,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Sahar Fatima",[59],{"name":60,"class":6},"University of Lahore","100609646","complete-decongestive-therapy-versus-non-pneumatic-compression-therapy-in-post-mastectomy-lymphedema-100609646",false,"NCT07217288","Complete Decongestive Therapy Versus Non-pneumatic Compression Therapy in Post Mastectomy Lymphedema","Effectiveness of Complete Decongestive-versus Non-pneumattic- Compression Therapy in Patients With Post-mastectomy Lymphedema","CDT","Inclusion Criteria:\n\n* Females with age between 30 to 60 years. (Monticciolo et al., 2021)\n* Females with unilateral mastectomy post three months of surgery. (Shen et al., 2023) 21\n* A volume difference to the circumferential measurements between the affected and unaffected upper extremities of more volume difference\\>10%.\n* Completed chemotherapy and\u002For radiation therapy. (Borman, Yaman, Yasrebi, İnanlı, \\& Dönmez, 2022)\n\nExclusion Criteria:\n\n* Systemic disorders that might contraindicate the use of sequential compression therapy i.e. chronic kidney disease with renal failure, Congestive heart failure, neurological disorders, respiratory disorders.\n* Presence of active cellulitis, open and partially healed wounds.\n* Patients with lipedema\n* Active or recurrent cancer (defined as \\\u003C 3 months since completion of cancer therapy)\n* An acute infection within the previous 4 weeks\n* Active venous thromboembolic edema\n* Pregnant women and women who are planning or nursing at study entry.\n* Patients who had participated in any clinical trial of an investigational substance or device during the previous 30 days\n* Potential patients with a cognitive or physical impairment that would interfere with appropriate use of the device. (Rockson, Whitworth, et al., 2022)","FEMALE","30 Years","60 Years",{"count":73,"type":74},52,"ESTIMATED","INTERVENTIONAL",[77],"NA","The aim of the study is to compare the effectiveness of Complete Decongestive Therapy and Non-Pneumatic Compression Therapy, both combined with routine physical therapy, in reducing pain and edema volume, improving range of motion, respiratory function, inflammatory markers, and overall quality of life in patients with post-mastectomy lymphedema.",[80,81,82],"Lymphedema, Breast Cancer","Mastectomy Related Lymphedema","Post Mastectomy Lymphedema","NOT_YET_RECRUITING","2025-10-14",{"date":86,"type":87},"2025-10-15","ACTUAL",{"date":89,"type":74},"2025-10-26",{"date":91,"type":74},"2027-04-30",{"name":5,"class":6},1]