[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100503431":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":26,"responsibleParty":31,"collaborators":33,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":26,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":26,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":26,"overallStatus":73,"whyStopped":26,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":26},{"fullName":5,"class":6},"China National Center for Cardiovascular Diseases","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Inferior part-sternotomy CABG","EXPERIMENTAL","A midline skin incision of 8 to 10cm in length is made over the sternum, starting from 2-3cm below the sternal angle inferiorly and extending slightly beyond the xiphoid process. A sternal saw is used to split the sternum from the xiphoid process to the second intercostal space where the sternum is partially transected by turning the saw rightward. Left internal mammary artery (LIMA)-left anterior descending branch bypass is the first choice for all patients. Remaining coronary bypassing techniques are according to clinical practice and preference of the operator. If it is difficult to perform CABG via inferior part-sternotomy, the treatment strategy convert to full median sternotomy, which is deemed to be failed to achieve complete revascularization via inferior part-sternotomy.",[13],"Procedure: Inferior part-sternotomy",{"label":15,"type":16,"description":17,"interventionNames":18},"Full median sternotomy CABG","ACTIVE_COMPARATOR","A midline skin incision is made over the sternum, starting from the sternal angle and extending slightly beyond the xiphoid process. The sternum is fully split by a sternal saw. Remaining coronary bypassing techniques are same in both groups according to clinical practice and preference of the operator.",[19],"Procedure: Full median sternotomy",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Inferior part-sternotomy","A midline skin incision of 8 to 10cm in length is made over the sternum, starting from 2-3cm below the sternal angle inferiorly and extending slightly beyond the xiphoid process. A sternal saw is used to split the sternum from the xiphoid process to the second intercostal space where the sternum is partially transected by turning the saw rightward.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Full median sternotomy","A midline skin incision is made over the sternum, starting from the sternal angle and extending slightly beyond the xiphoid process. The sternum is fully split by a sternal saw.",[15],{"type":32,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[34,37,39,42,44,46,48,50],{"name":35,"class":36},"Tangshan Central Hospital","OTHER",{"name":38,"class":36},"Baotou Central Hospital",{"name":40,"class":41},"Xiamen Second Hospital","UNKNOWN",{"name":43,"class":36},"Beijing Shijitan Hospital, Capital Medical University",{"name":45,"class":36},"Peking University International Hospital",{"name":47,"class":36},"Shenzhen Sun Yat-sen Cardiovascular Hospital",{"name":49,"class":36},"Fuwai Yunnan Cardiovascular Hospital",{"name":51,"class":36},"Henan Provincial People's Hospital","100503431","complete-revascularization-via-inferior-part-sternotomy-100503431",false,"NCT05835167","Complete Revascularization Via Inferior Part-sternotomy","Minimally Invasive Coronary Artery Bypass Grafting Achieving Complete Revascularization of Multivessel Coronary Artery Disease Via Inferior Part-Sternotomy (The ACRIS-MICABG Trial)","Inclusion Criteria:\n\nPatients who undergo primary isolated open-chest CABG with multi-vessel coronary disease(left main artery disease with right coronary artery disease,or three-vessel disease)\n\nExclusion Criteria:\n\n1. Single vessel disease, double vessel disease, left main artery disease without right coronary artery disease.\n2. Concomitant cardiac surgeries(i.e. valve repair or replacement, Maze surgery, left ventricular repair due to ventricular aneurysm).\n3. Redo CABG.\n4. Emergent CABG.\n5. Left ventricular ejection fraction(EF≤35%).\n6. Severe atherosclerosis of the ascending aorta.\n7. Subjects tend to choose surgical approach (via full median sternotomy\u002Finferior part-sternotomy) .\n8. Malignant tumor or other severe systemic diseases.\n9. Severe renal insufficiency (i.e. creatinine \\>200 μmol\u002FL).\n10. Contraindications for dual antiplatelet therapy, such as active gastroduodenal ulcer.\n11. Participant of other ongoing clinical trials.","ALL","18 Years","80 Years",{"count":63,"type":64},260,"ESTIMATED","INTERVENTIONAL",[67],"NA","To verify the effectiveness and safety of minimally invasive coronary artery bypass grafting for complete revascularization of multivessel coronary artery disease via inferior part-sternotomy, We aim to randomize 260 patients undergoing isolated Coronary artery bypass grafting (CABG) to compare the ratios of complete revascularization between inferior part-sternotomy CABG and full median sternotomy CABG from 9 hospitals in China.",[70,71,72],"Complete Revascularization","Coronary Artery Bypass Grafting","Multivessel Coronary Artery Disease","NOT_YET_RECRUITING","2023-04-27",{"date":76,"type":77},"2023-04-28","ACTUAL",{"date":79,"type":64},"2023-05-05",{"date":81,"type":64},"2035-05-04",{"name":5,"class":6}]