[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551527":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":60,"collaborators":62,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":24,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":24,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"National University Hospital, Singapore","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Very Low Calorie Diet Ready-to-eat (VLCD RTE) meals","EXPERIMENTAL","Participants (n=70) in the VLCD RTE meals group will be advised to follow a calorie-restricted healthy ketogenic diet , consuming a maximum of 800 calories and 50g net carbohydrate intake daily.\n\nParticipants will be provided with VLCD RTE meals for lunch and dinner for 4 weeks and advised on a healthy keto breakfast.\n\nThe participants will be expected to self-monitor their weight, physical activity and diet logs via the nutritionist buddy keto app. There will be in app virtual reminders (automated and by dietitians via the chat function) sent via the nutritionist buddy keto application for the 1 month for participants to log in their weight and meals.",[13],"Other: Very Low Calorie Diet Ready-to-eat (VLCD RTE) meals",{"label":15,"type":16,"description":17,"interventionNames":18},"Liquid Meal Replacement","ACTIVE_COMPARATOR","Participants (n=70) in the liquid meal replacement group will be advised to follow very low-calorie diet, with a maximum of 800 calories and 50g net carbohydrate intake daily.\n\nParticipants will be provided with a liquid meal replacement for breakfast, lunch, and dinner for 4 weeks. Additionally, patients are to prepare 1 serving of non-starchy vegetables are to be included for lunch and dinner.\n\nThe participants will be expected to self-monitor their weight, physical activity and diet logs via the nutritionist buddy keto app. There will be in app virtual reminders (automated and by dietitians via the chat function) sent via the nutritionist buddy keto application for the 1 month for participants to log in their weight and meals.",[19],"Other: Standard Care Group",[21,25],{"type":6,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"Participants will be provided with VLCD RTE meals for lunch and dinner for 4 weeks and advised on a healthy ketogenic breakfast. Participant will be expected to adhere to VLCD regimen containing 800 calories per day or fewer and keep within 50g net carbohydrates a day.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Standard Care Group","Participants will be provided with liquid meal replacement for breakfast, lunch, and dinner for 4 weeks. Additionally, patients are to prepare 1 serving of non-starchy vegetables are to be included for lunch and dinner. Participant will be expected to adhere to VLCD regimen containing 800 calories per day or fewer and keep within 50g net carbohydrates a day.",[15],[30],{"name":31,"affiliation":5,"role":32},"Melissa Tay","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Melissa Tay Hui Juan","CONTACT","67725166","melissa_hj_tay@nuhs.edu.sg",[40,53],{"facility":41,"status":42,"city":43,"state":24,"zip":24,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Alexandra Hospital","RECRUITING","Singapore","SG",{"type":46,"coordinates":47},"Point",[48,49],103.85007,1.28967,{"lat":49,"lon":48},[52],{"name":31,"role":36,"phone":24,"phoneExt":24,"email":24},{"facility":54,"status":42,"city":43,"state":24,"zip":24,"country":43,"countryCode":44,"cosmosGeoPoint":55,"geoPoint":57,"contacts":58},"National University Hospital",{"type":46,"coordinates":56},[48,49],{"lat":49,"lon":48},[59],{"name":31,"role":36,"phone":24,"phoneExt":24,"email":24},{"type":61,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[63],{"name":41,"class":6},"100551527","compliance-with-standard-care-vs-ready-to-eat-meals-prior-to-bariatric-surgery-100551527",false,"NCT06461247","Compliance With Standard Care vs Ready to Eat Meals Prior to Bariatric Surgery","Compliance With Standard Care vs Ready to Eat Meals Prior to Bariatric Surgery - a Randomised Controlled Trial","Inclusion Criteria:\n\n* Adults aged 21 to 65 years old\n* Scheduled for bariatric surgery at least 1 month prior\n* BMI ≥ 27.5 kg\u002Fm2 (with type 2 diabetes mellitus or metabolic syndrome)\n* Owns a smart phone with data plan\n* English speaking\n\nExclusion Criteria:\n\n* Cognitive impairment.\n* Hypothyroidism\n* Chronic kidney disease\n* Hypothyroidism\n* Depression with ongoing psychology follow up\n* Type 1 diabetes\n* Liver Cirrhosis\n* Pregnancy\n* Heart Failure\n* Active cancer or in remission for less than 5 years\n* Vegetarian\n* Observing the fast during the month of Ramadan\n* Undergoing treatment with anti obesity medications (eg: Phentermine\u002FOrlistat\u002FContrave\u002FGLP-1 analogues etc)",true,"ALL","21 Years","65 Years",{"count":76,"type":77},140,"ESTIMATED","INTERVENTIONAL",[80],"NA","Currently, a ketosis-inducing programme, usually a liquid meal replacement, is the standard of care for pre-operative dietary management. However, compliance with liduiqd meal replacement is challenging primarily due to individual taste preferences, limited variety, having to take a liquid diet, lifestyle factors, and other obstacles. Therefore, there is a need for RTE meals to enhance patient satisfaction and compliance, ultimately resulting in improved pre-operative weight loss outcomes. Hence, this RCT study aims to determine whether Very Low Calorie Diet Ready-to-eat (VLCD RTE) meals would lead to greater compliance as measured by blood ketones and meal logging via Nutritionist Buddy app (nBuddy App) compared to standard care liquid meal replacement (Optifast) prior to bariatric surgery.",[83],"Bariatric Surgery Candidate",[85,86,87],"Weight loss","Very Low Calorie Diet","Body Weight","2025-09-05",{"date":90,"type":91},"2025-09-12","ACTUAL",{"date":93,"type":91},"2024-07-01",{"date":95,"type":77},"2026-09",{"name":5,"class":6},2]