[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100316694":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":33,"centralContacts":43,"locations":54,"responsibleParty":326,"collaborators":331,"id":358,"slug":359,"hasResults":360,"nctId":361,"briefTitle":362,"officialTitle":363,"acronym":364,"eligibilityCriteria":365,"healthyVolunteers":366,"sex":367,"minAge":368,"maxAge":369,"enrollmentInfo":370,"targetDuration":10,"studyType":373,"phases":10,"briefSummary":374,"conditions":375,"keywords":385,"overallStatus":57,"whyStopped":10,"lastUpdateSubmitDate":394,"lastUpdatePostDateStruct":395,"startDateStruct":398,"completionDateStruct":400,"leadSponsor":402,"locationsCount":403},{"fullName":5,"class":6},"McGill University","OTHER",[8,12,15,18,21,24,27,30],{"label":9,"type":10,"description":11,"interventionNames":10},"Normal healthy elderly",null,"participants with no subjective or objective cognitive deficits or decline.",{"label":13,"type":10,"description":14,"interventionNames":10},"Subjective Cognitive Decline","Participants with a complaint of subjective cognitive impairment, but no objective evidence of such.",{"label":16,"type":10,"description":17,"interventionNames":10},"Mild Cognitive Impairment (MCI)","Participants with objective evidence of cognitive impairment, but it does not impact on daily function.",{"label":19,"type":10,"description":20,"interventionNames":10},"Vascular MCI","Participants meeting criteria of MCI who also show signs of cerebrovascular disease on imaging but have no history of stroke.",{"label":22,"type":10,"description":23,"interventionNames":10},"Alzheimer's Disease","Participants with dementia of the Alzheimer's type according to the National Institute of Aging-Alzheimer's Association criteria",{"label":25,"type":10,"description":26,"interventionNames":10},"Dementia of Mixed Etiology","Participants with dementia and evidence of more than one etiology.",{"label":28,"type":10,"description":29,"interventionNames":10},"Lewy Body\u002FParkinson's spectrum","Participants with Parkinson's disease who show mild or moderate cognitive impairment and\u002For dementia.",{"label":31,"type":10,"description":32,"interventionNames":10},"Frontotemporal dementia (FTD) spectrum","Participants with behavioral variant FTD, primary progressive aphasia, progressive supranuclear palsy, or corticobasal syndrome",[34,38,41],{"name":35,"affiliation":36,"role":37},"Michael Borrie, MD","Western University","STUDY_DIRECTOR",{"name":39,"affiliation":40,"role":37},"Natalie Philips, PhD","Concordia University, Montreal",{"name":42,"affiliation":36,"role":37},"Jaspreet Bhangu, MB",[44,50],{"name":45,"role":46,"phone":47,"phoneExt":48,"email":49},"Howard Chertkow, MD","CONTACT","514 340 8222","25129","howard.chertkow@mcgill.ca",{"name":51,"role":46,"phone":52,"phoneExt":10,"email":53},"Randi Pilon","514 8339709","Randi.Pilon@ladydavis.ca",[55,74,92,111,131,150,166,182,198,208,217,226,232,248,257,267,283,298,317],{"facility":56,"status":57,"city":58,"state":59,"zip":60,"country":61,"countryCode":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"University of Calgary","RECRUITING","Calgary","Alberta","T2N 1N4","Canada","CA",{"type":64,"coordinates":65},"Point",[66,67],-114.08529,51.05011,{"lat":67,"lon":66},[70],{"name":71,"role":46,"phone":72,"phoneExt":10,"email":73},"Eric E Smith, MD","403.944.1594","eric.smith@albertahealthservices.ca",{"facility":75,"status":57,"city":76,"state":59,"zip":77,"country":61,"countryCode":62,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"University of Alberta Hospital","Edmonton","T6G 2B7",{"type":64,"coordinates":79},[80,81],-113.46871,53.55014,{"lat":81,"lon":80},[84,88],{"name":85,"role":46,"phone":86,"phoneExt":10,"email":87},"Richard Camicioli, MD","(780) 248-1774","rcamicio@ualberta.ca",{"name":89,"role":46,"phone":90,"phoneExt":10,"email":91},"Krista Nelles, B. A.","(780) 248-2043","knelles@ualberta.ca",{"facility":93,"status":57,"city":94,"state":95,"zip":96,"country":61,"countryCode":62,"cosmosGeoPoint":97,"geoPoint":101,"contacts":102},"Djavad Mowafaghian Centre for Brain Health","Vancouver","British Columbia","V6T 1Z3",{"type":64,"coordinates":98},[99,100],-123.11934,49.24966,{"lat":100,"lon":99},[103,107],{"name":104,"role":46,"phone":105,"phoneExt":10,"email":106},"Robin Hsiung, MD","604-822-3610","hsiung@mail.ubc.ca",{"name":108,"role":46,"phone":109,"phoneExt":10,"email":110},"Mannie Fan, M.Sc.","604-822-0550","mannie.fan@vch.ca",{"facility":112,"status":113,"city":114,"state":95,"zip":115,"country":61,"countryCode":62,"cosmosGeoPoint":116,"geoPoint":120,"contacts":121},"Island Health","NOT_YET_RECRUITING","Victoria","V8R 6R3",{"type":64,"coordinates":117},[118,119],-123.35155,48.4359,{"lat":119,"lon":118},[122,126],{"name":123,"role":46,"phone":124,"phoneExt":10,"email":125},"Alexandre Henri-Bhargava, MD","(778) 265-6111","alexhb@uvic.ca",{"name":127,"role":46,"phone":128,"phoneExt":129,"email":130},"Karen Coles, RN","250.370-8111","13630","karen.coles@viha.ca",{"facility":132,"status":57,"city":133,"state":134,"zip":135,"country":61,"countryCode":62,"cosmosGeoPoint":136,"geoPoint":140,"contacts":141},"Veteran's Memorial Building","Halifax","Nova Scotia","B3E 2E1",{"type":64,"coordinates":137},[138,139],-63.57688,44.64269,{"lat":139,"lon":138},[142,146],{"name":143,"role":46,"phone":144,"phoneExt":10,"email":145},"Maia von Maltzahn, MD","902-473-2495","Maia.Maltzahn@nshealth.ca",{"name":147,"role":46,"phone":148,"phoneExt":10,"email":149},"Jodie Penwarden, MFSGN","902-473-7705","Jodie.Penwarden@nshealth.ca",{"facility":151,"status":57,"city":152,"state":153,"zip":154,"country":61,"countryCode":62,"cosmosGeoPoint":155,"geoPoint":159,"contacts":160},"Hamilton General Hospital","Hamilton","Ontario","L8L 2X2",{"type":64,"coordinates":156},[157,158],-79.84963,43.25011,{"lat":158,"lon":157},[161],{"name":162,"role":46,"phone":163,"phoneExt":164,"email":165},"Demetrios Sahlas, MD","905-521-2100","46373","sahlas@mcmaster.ca",{"facility":167,"status":57,"city":168,"state":153,"zip":169,"country":61,"countryCode":62,"cosmosGeoPoint":170,"geoPoint":174,"contacts":175},"St. Joseph's Health Care London","London","N6A 4V2",{"type":64,"coordinates":171},[172,173],-81.23304,42.98339,{"lat":173,"lon":172},[176,179],{"name":35,"role":46,"phone":177,"phoneExt":10,"email":178},"(519) 685-4021","michael.borrie@sjhc.london.on.ca",{"name":180,"role":46,"phone":10,"phoneExt":10,"email":181},"Kayla Vander Ploeg","kayla.vanderploeg@sjhc.london.on.ca",{"facility":183,"status":57,"city":168,"state":153,"zip":184,"country":61,"countryCode":62,"cosmosGeoPoint":185,"geoPoint":187,"contacts":188},"Gait and Brain Lab","N6C 5J1",{"type":64,"coordinates":186},[172,173],{"lat":173,"lon":172},[189,194],{"name":190,"role":46,"phone":191,"phoneExt":192,"email":193},"Manuel Montero-Odasso, MD","519.685.4292","42369","mmontero@uwo.ca",{"name":195,"role":46,"phone":191,"phoneExt":196,"email":197},"Abbie Barron, BA","42179","Abbie.Barron@sjhc.london.on.ca",{"facility":199,"status":200,"city":201,"state":153,"zip":202,"country":61,"countryCode":62,"cosmosGeoPoint":203,"geoPoint":207,"contacts":10},"Bruyère Research Institute","ACTIVE_NOT_RECRUITING","Ottawa","K1N 5C8",{"type":64,"coordinates":204},[205,206],-75.69812,45.41117,{"lat":206,"lon":205},{"facility":209,"status":200,"city":210,"state":153,"zip":211,"country":61,"countryCode":62,"cosmosGeoPoint":212,"geoPoint":216,"contacts":10},"Kawartha Centre","Peterborough","K9H 2P4",{"type":64,"coordinates":213},[214,215],-78.31623,44.30012,{"lat":215,"lon":214},{"facility":218,"status":200,"city":219,"state":153,"zip":220,"country":61,"countryCode":62,"cosmosGeoPoint":221,"geoPoint":225,"contacts":10},"Sunnybrook Health Sciences Centre","Toronto","M4N 3M5",{"type":64,"coordinates":222},[223,224],-79.39864,43.70643,{"lat":224,"lon":223},{"facility":227,"status":200,"city":219,"state":153,"zip":228,"country":61,"countryCode":62,"cosmosGeoPoint":229,"geoPoint":231,"contacts":10},"University Health Network Memory Clinic","M5T 2S8",{"type":64,"coordinates":230},[223,224],{"lat":224,"lon":223},{"facility":233,"status":57,"city":219,"state":153,"zip":234,"country":61,"countryCode":62,"cosmosGeoPoint":235,"geoPoint":237,"contacts":238},"Baycrest Clinical Unit","M6A 1W1",{"type":64,"coordinates":236},[223,224],{"lat":224,"lon":223},[239,243],{"name":240,"role":46,"phone":241,"phoneExt":242,"email":49},"Howard Chertkow, PhD","(416)785-2500","3956",{"name":244,"role":46,"phone":245,"phoneExt":246,"email":247},"Paramjeet Sandhu","(416) 785-2500","3904","psandhu@research.baycrest.org",{"facility":249,"status":200,"city":250,"state":153,"zip":251,"country":61,"countryCode":62,"cosmosGeoPoint":252,"geoPoint":256,"contacts":10},"University of Waterloo","Waterloo","N2L 3G1",{"type":64,"coordinates":253},[254,255],-80.51639,43.4668,{"lat":255,"lon":254},{"facility":258,"status":200,"city":259,"state":260,"zip":261,"country":61,"countryCode":62,"cosmosGeoPoint":262,"geoPoint":266,"contacts":10},"Research Institute of the McGill University Health Centre","Montreal","Quebec","H3G 1A4",{"type":64,"coordinates":263},[264,265],-73.58781,45.50884,{"lat":265,"lon":264},{"facility":268,"status":57,"city":259,"state":260,"zip":269,"country":61,"countryCode":62,"cosmosGeoPoint":270,"geoPoint":272,"contacts":273},"Jewish General Hospital\u002FMcGill Memory Clinic","H3T 1E2",{"type":64,"coordinates":271},[264,265],{"lat":265,"lon":264},[274,278],{"name":275,"role":46,"phone":47,"phoneExt":276,"email":277},"Susan Vaitekunas, MD","24734","svaitekunas@jgh.mcgill.ca",{"name":279,"role":46,"phone":280,"phoneExt":281,"email":282},"Chris Hosein, M.Ed","514 304 8222","23621","chosein@jgh.mcgill.ca",{"facility":284,"status":57,"city":259,"state":260,"zip":285,"country":61,"countryCode":62,"cosmosGeoPoint":286,"geoPoint":288,"contacts":289},"Clinique de cognition Institut universitaire de gériatrie de Montréal","H3W 1W5",{"type":64,"coordinates":287},[264,265],{"lat":265,"lon":264},[290,295],{"name":291,"role":46,"phone":292,"phoneExt":293,"email":294},"Marie-Jeanne Kergoat, MD","514 340-3540","2811","marie-jeanne.kergoat@umontreal.ca",{"name":296,"role":46,"phone":10,"phoneExt":10,"email":297},"Sylvie Belleville","sylvie.belleville@umontreal.ca",{"facility":299,"status":57,"city":300,"state":260,"zip":301,"country":61,"countryCode":62,"cosmosGeoPoint":302,"geoPoint":306,"contacts":307},"Hôpital Enfant-Jésus","Québec","G1J 1Z4",{"type":64,"coordinates":303},[304,305],-71.21454,46.81228,{"lat":305,"lon":304},[308,312],{"name":309,"role":46,"phone":310,"phoneExt":10,"email":311},"Louis Verret, MD","418-649-5980","verretl@videotron.ca",{"name":313,"role":46,"phone":314,"phoneExt":315,"email":316},"Nancy Parent, RN","418 649-0252","63711","nancy.parent.cha@ssss.gouv.qc.ca",{"facility":318,"status":200,"city":319,"state":260,"zip":320,"country":61,"countryCode":62,"cosmosGeoPoint":321,"geoPoint":325,"contacts":10},"Centre de recherche sur le vieillissement CIUSSS de l'Estrie-CHUS","Sherbrooke","J1J3H5",{"type":64,"coordinates":322},[323,324],-71.89908,45.40008,{"lat":324,"lon":323},{"type":327,"investigatorFullName":328,"investigatorTitle":329,"investigatorAffiliation":330,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Howard Chertkow","Principal Investigator","Baycrest",[332,335,337,340,342,344,346,348,350,352,354,356],{"name":333,"class":334},"Canadian Institutes of Health Research (CIHR)","OTHER_GOV",{"name":336,"class":6},"Alzheimer Society of Canada",{"name":338,"class":339},"Sanofi","INDUSTRY",{"name":341,"class":6},"New Brunswick Health Research Foundation",{"name":343,"class":6},"Saskatchewan Health Research Foundation",{"name":345,"class":6},"Michael Smith Foundation for Health Research",{"name":347,"class":334},"Nova Scotia Health Research Foundation",{"name":349,"class":339},"Eli Lilly and Company",{"name":351,"class":6},"Canadian Nurses Foundation (CNF)",{"name":353,"class":6},"Ontario Brain Institute",{"name":355,"class":339},"Pfizer",{"name":357,"class":6},"Canadian Consortium on Neurodegeneration in Aging","100316694","comprehensive-assessment-of-neurodegeneration-and-dementia-100316694",false,"NCT03402919","Comprehensive Assessment of Neurodegeneration and Dementia","The Comprehensive Assessment of Neurodegeneration and Dementia Study","COMPASS-ND","Inclusion Criteria:\n\n* Has subjective or objective cognitive impairment\n* Written informed consent must be obtained and documented (from the patient or, where jurisdictions allow it, from a caregiver\u002Ffamily member)\n* Sufficient proficiency in English or French to undertake self report and neuropsychological testing\n* Geographic accessibility to the study site\n* Must have a study partner who can participate as required in the protocol (provide corroborative information)\n* Up to 12 years of education\n* Fits into one of the following groups: Cognitively Unimpaired, Subjective Cognitive Impairment, Mild Cognitive Impairment, Vascular Mild Cognitive Impairment, Parkinson's Disease, Parkinson's Disease with Mild Cognitive Impairment\n\nExclusion Criteria:\n\n* The presence of other significant known chronic brain disease such as: moderate to severe chronic static leukoencephalopathy (including previous traumatic injury), multiple sclerosis, a serious developmental handicap, malignant tumors, Parkinson's disease (other than for the Parkinson's cohort), and other rarer brain illnesses\n* Ongoing alcohol or drug abuse which in the opinion of the investigator may interfere with the subject's ability to comply with the study procedures\n* Symptomatic stroke within the previous year\n* Unable to undergo MRI scan due to medical contraindications or inability to tolerate the procedure",true,"ALL","50 Years","90 Years",{"count":371,"type":372},1573,"ESTIMATED","OBSERVATIONAL","This is a longitudinal observational study recruiting individuals between the ages of 50 and 90 with different types of dementia as well as a comparison group without cognitive deficits. Participants are\u002Fwill be recruited at sites across Canada and will undergo assessments, neuroimaging, and biological sample collection.",[376,16,377,378,379,380,381,382,383,384],"Dementia","Subjective Cognitive Impairment","Parkinson's Disease (PD)","Lewy Body Disease(LBD)","Mixed Dementia","Frontotemporal Dementia (FTD)","Alzheimer Disease (AD)","Cognitively Unimpaired","Subjective Cognitive Decline (SCD)",[386,376,22,387,388,389,390,391,392,393],"Observational","Parkinson's Disease","Biosample","Genetics","Neuropsychological","MRI","Microbiome","Plasma","2026-01-15",{"date":396,"type":397},"2026-01-20","ACTUAL",{"date":399,"type":397},"2016-06",{"date":401,"type":372},"2029-12",{"name":5,"class":6},19]