[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619034":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":25,"responsibleParty":43,"collaborators":46,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":78,"sex":79,"minAge":80,"maxAge":10,"enrollmentInfo":81,"targetDuration":10,"studyType":84,"phases":10,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":91,"whyStopped":10,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Beijing Anzhen Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"SDB Comprehensive Management Cohort",null,"This is a multi-center, prospective, observational registration cohort of 11,100 adult patients (age ≥ 18). All participants must have completed sleep breathing monitoring within one month prior to enrollment. The cohort aims to establish a clinical database and biobank to explore SDB-related biomarkers and pathogenesis. Participants receive comprehensive clinical management, including potential treatments for SDB, such as continuous positive airway pressure (CPAP), oral appliances, surgery, or lifestyle interventions. Data on clinical baselines, sleep monitoring, laboratory tests, and imaging will be collected. Follow-up will be conducted for up to 5 years (at baseline, 3 months, 1 year, and annually thereafter) to evaluate clinical outcomes, including all-cause mortality and cardiovascular events.",[13],"Other: Clinical Management for SDB",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Clinical Management for SDB","Participants receive standard clinical care and management for sleep-disordered breathing according to established clinical guidelines. This may include, but is not limited to, CPAP therapy, lifestyle modifications, oral appliances, or other medical interventions as determined by the treating physician.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Shao-Ping Nie, MD, PhD","CONTACT","86-10-84005256","spnie@ccmu.edu.cn",[26],{"facility":27,"status":10,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Beijing Anzhen Hospital, Capital Medical University","Beijing","Beijing Municipality","100029","China","CN",{"type":34,"coordinates":35},"Point",[36,37],116.39723,39.9075,{"lat":37,"lon":36},[40,41],{"name":21,"role":22,"phone":10,"phoneExt":23,"email":24},{"name":21,"role":42,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"type":42,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Shao-Ping Nie","Professor of Medicine",[47,50,52,54,56,58,60,62,64,66,68],{"name":48,"class":49},"Beijing Hospital","OTHER_GOV",{"name":51,"class":6},"Second Xiangya Hospital of Central South University",{"name":53,"class":6},"Peking University Hospital of Stomatology",{"name":55,"class":6},"Shantou University Medical College",{"name":57,"class":6},"Shanghai Institute of Hypertension",{"name":59,"class":6},"First Affiliated Hospital of Fujian Medical University",{"name":61,"class":6},"Beijing Tiantan Hospital",{"name":63,"class":6},"Beijing Jishuitan Hospital",{"name":65,"class":6},"Beijing Friendship Hospital",{"name":67,"class":6},"West China Hospital",{"name":69,"class":6},"Beijing Chao Yang Hospital","100619034","comprehensive-care-of-sleep-disordered-breathing-100619034",false,"NCT07339371","Comprehensive Care of Sleep Disordered Breathing","A Prospective Cohort Study on Comprehensive Care of Sleep Disordered Breathing (Care-SDB Study)","Care-SDB","Inclusion Criteria:\n\n* Age ≥ 18 years.\n* Patients who have completed sleep breathing monitoring within 1 month prior to enrollment.\n* Capable of providing signed informed consent.\n\nExclusion Criteria:\n\n* Estimated life expectancy of less than 3 months.\n* Refusal to participate in the study.\n* Inability to cooperate with baseline data collection or follow-up evaluations.",true,"ALL","18 Years",{"count":82,"type":83},11100,"ESTIMATED","OBSERVATIONAL","The Comprehensive Care of Sleep Disordered Breathing study (Care-SDB) is a prospective, multi-center, registry-based cohort study designed to investigate the integrated management of sleep-disordered breathing (SDB). The investigators aim to establish a nationwide SDB cohort and biobank to identify prognostic biomarkers, explore pathogenic mechanisms, and evaluate optimal treatment models. A total of 11,100 adult patients with recent sleep monitoring will be enrolled and followed longitudinally for up to 5 years. Data collection, including clinical outcomes and major adverse events, will be managed via a unified Electronic Data Capture platform. The results from Care-SDB are expected to provide critical evidence-based guidance for the risk stratification, standardized intervention, and personalized management of patients with sleep-disordered breathing.",[87],"Sleep Disordered Breathing (SDB)",[89,90],"Comprehensive Care","Sleep Disordered Breathing","NOT_YET_RECRUITING","2026-01-19",{"date":94,"type":95},"2026-01-21","ACTUAL",{"date":97,"type":83},"2026-01-01",{"date":99,"type":83},"2029-01-01",{"name":5,"class":6},1]