[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100496084":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":33,"locations":43,"responsibleParty":60,"collaborators":24,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":24,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":24,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":24,"overallStatus":46,"whyStopped":24,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"National Cheng-Kung University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Sleep Hygiene Education","SHAM_COMPARATOR","Participants will received once per month of sleep hygiene education for three months.",[13],"Other: Sleep hygiene education",{"label":15,"type":16,"description":17,"interventionNames":18},"Comprehensive Respiratory Training Exercise Program","EXPERIMENTAL","Participants will received Comprehensive Respiratory Training Exercise Program twice per weeks for three months.",[19],"Other: Comprehensive Respiratory Training Exercise Program",[21,25],{"type":6,"name":15,"description":22,"armGroupLabels":23,"otherNames":24},"This comprehensive respiratory training exercise program consists of four main components, including oropharyngeal muscle training, respiratory muscle training, aerobic exercise, and sleep hygiene education.",[15],null,{"type":6,"name":26,"description":26,"armGroupLabels":27,"otherNames":24},"Sleep hygiene education",[9],[29],{"name":30,"affiliation":31,"role":32},"Ching-Hsia Hung, PhD","National Cheng Kung University","PRINCIPAL_INVESTIGATOR",[34,39],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Jun-Hui Ong, MS","CONTACT","+886-9-37839992","junhui.ong611@gmail.com",{"name":30,"role":36,"phone":40,"phoneExt":41,"email":42},"+886-6-2353535","5939","chhung@mail.ncku.edu.tw",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":48,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"National Cheng Kung University Hospital","RECRUITING","Tainan","Taiwan","704","TW",{"type":52,"coordinates":53},"Point",[54,55],120.21333,22.99083,{"lat":55,"lon":54},[58],{"name":30,"role":36,"phone":59,"phoneExt":41,"email":42},"06-2353535",{"type":61,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100496084","comprehensive-respiratory-training-exercise-program-in-obstructive-sleep-apnea-100496084",false,"NCT05739617","Comprehensive Respiratory Training Exercise Program in Obstructive Sleep Apnea","Combining Sonography to Explore the Therapeutic Effect and Mechanism of a Comprehensive Respiratory Training Exercise Program on Cardiorespiratory Endurance and Airway Muscle Function in Obstructive Sleep Apnea","Inclusion Criteria:\n\n* Newly diagnosed with OSA (AHI≥ 5 events per hour)\n* Age between 20 to 65 years old\n* BMI of 18-30 kg.m-2\n\nExclusion Criteria: Diagnosed with any of the following diseases below:\n\n* Central or mixed types of sleep apnea\n* Neuromuscular disease\n* Severe cardiovascular disease\n* Active psychiatric disease\n* Head or neck disease or cancer\n* Structural abnormalities over the upper respiratory airway\n* Performed any operation or treatment over the neck before\n* Pregnancy","ALL","20 Years","65 Years",{"count":73,"type":74},150,"ESTIMATED","INTERVENTIONAL",[77],"NA","Obstructive sleep apnea (OSA) is a multi-factorial sleep disorder. Complete collapse or partial collapse in the airway increases the risk of developing cardiovascular and kidney-related disease in OSA patients. Resulting in an increase in medical expenses and workload for the healthcare worker. Multilevel of upper airway muscles especially the genioglossus muscle showed to contribute to airway obstruction as it fatigues easily. The endurance level of OSA patients was shown to be significantly lower. Therefore, the goal of this experimental study is to assess the feasibility and effectiveness of a comprehensive respiratory training exercise program on cardiorespiratory endurance, airway muscle function, and sleep parameters in patients with obstructive sleep apnea (OSA). Aside from exploring the therapeutic effect, the results of the study will be used to explore the mechanism of the treatment in relation to the changes in the OSA severity.",[80],"Obstructive Sleep Apnea of Adult","2025-06-15",{"date":83,"type":84},"2025-06-18","ACTUAL",{"date":86,"type":84},"2023-03-01",{"date":88,"type":74},"2026-07-16",{"name":5,"class":6},1]