[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100380089":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":66,"collaborators":69,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":89,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":26,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":111,"overallStatus":45,"whyStopped":26,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},{"fullName":5,"class":6},"Bispebjerg Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Specific computer-based cognitive rehabilitation","EXPERIMENTAL","154 patients will be allocated to specific computer-based cognitive rehabilitation. This group will train with 10 exercises from the cognitive rehabilitation software 'Scientific Brain training PRO'. These 10 exercises are designed to train various executive functions.",[13],"Behavioral: Computer-based cognitive rehabilitation (CBCR)",{"label":15,"type":16,"description":17,"interventionNames":18},"General computer-based cognitive stimulation","ACTIVE_COMPARATOR","154 patients will be allocated to general computer-based cognitive stimulation. This group will train with 10 generally mentally stimulating games on a website specifically designed for this trial. These 10 games are chosen because they are believed to have a low load on executive functions but stimulate over-all concentration and visuoperceptual abilities.",[19],"Behavioral: General computer-based cognitive stimulation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Computer-based cognitive rehabilitation (CBCR)","CBCR are software-programmes for computers which are clinically developed for rehabilitation of various cognitive functions.",[9],null,{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":26},"For this trial we have developed a webpage for general cognitive stimulation, which is designed to provide general computer-based cognitive stimulation.",[15],[31],{"name":32,"affiliation":5,"role":33},"Hanne Christensen, Professor","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":26,"email":38},"CONTACT","+45 38 63 50 70","hanne.krarup.christensen@regionh.dk",{"name":40,"role":36,"phone":41,"phoneExt":26,"email":42},"Katrine Sværke, M.Sc. Psych.","004521251087","katrine.svaerke.schioeler@regionh.dk",[44,58],{"facility":5,"status":45,"city":46,"state":26,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Copenhagen","Denmark","DK",{"type":50,"coordinates":51},"Point",[52,53],12.56553,55.67594,{"lat":53,"lon":52},[56],{"name":57,"role":36,"phone":26,"phoneExt":26,"email":26},"Hanne Christensen, MD, Professor",{"facility":59,"status":45,"city":46,"state":26,"zip":26,"country":47,"countryCode":48,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"Rigshospitalet",{"type":50,"coordinates":61},[52,53],{"lat":53,"lon":52},[64],{"name":65,"role":36,"phone":26,"phoneExt":26,"email":26},"Jesper Kjaergaard, MD",{"type":33,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Hanne Christensen","Professor",[70,72,74,76,78,81,83,85],{"name":71,"class":6},"Rigshospitalet, Denmark",{"name":73,"class":6},"University of Glasgow",{"name":75,"class":6},"University of Basel",{"name":77,"class":6},"Copenhagen Trial Unit, Center for Clinical Intervention Research",{"name":79,"class":80},"Hjernesagen","UNKNOWN",{"name":82,"class":6},"Göteborg University",{"name":84,"class":6},"Aalborg University Hospital",{"name":86,"class":6},"Neurorehabilitering - Kbh, City of Copenhagen","100380089","computer-assisted-self-training-to-improve-executive-function-100380089",false,"NCT04229056","COMPuter-assisted Self-training to Improve EXecutive Function","Computer-Assisted Self-Training to Improve Executive Function Versus Unspecific Training in Patients After Stroke, Cardiac Arrest or in Parkinson's Disease: a Randomized Controlled Trial","COMPEX","Inclusion Criteria:\n\n* A diagnose of stroke, cardiac arrest or Parkinson's disease.\n* Aged 18 years or older.\n* Impaired working memory measured with CABPad working memory test, cut off for inclusion: 5 symbols or less backwards\n* Computer and internet access at home.\n* Providing informed consent.\n\nInclusion criteria specific for stroke\n\n* Inclusion within 6 months post-stroke\n* Stroke confirmed by clinical findings and imaging, both AIS and ICH is allowed.\n* Initial stroke severity \\>\u002F= NIHSS 3.\n\nInclusion criteria specific for cardiac arrest\n\n• Inclusion within 6 months post ictus.\n\nInclusion criteria specific for Parkinson's disease\n\n* Clinical diagnosis of PD.\n* Anti-parkinsonian medical treatment (dopaminergic or other).\n\nExclusion Criteria:\n\n* Informed consent not provided\n* Other neurological or psychiatric disease which is expected to influence the patient's ability to participate in the trial according to the investigator\n* Not able to participate according to investigator\n\nExclusion criteria specific for stroke\n\n* Patients with massive anosognosia for executive dysfunction or patients with no subjective feeling of executive dysfunction (Patient sustains total denial of executive symptoms over time)\n* Patients with severe aphasia, in which it is unclear whether the patient's performance on a neuropsychological test-battery is due to aphasia and not executive dysfunction.\n\nExclusion criteria specific for cardiac arrest • None\n\nExclusion criteria specific for PD\n\n• Diagnosis of PD Dementia according to the MDS PD Dementia criteria","ALL","18 Years","100 Years",{"count":99,"type":100},307,"ESTIMATED","INTERVENTIONAL",[103],"NA","This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease. The effect of specialized CBCR is compared to generally cognitively stimulating activities on a computer",[106,107,108,109,110],"Parkinson Disease","Stroke","Cardiac Arrest","Cognitive Dysfunction","Executive Dysfunction",[112,113,114,115,116,117],"parkinson disease","stroke","cardiac arrest","executive dysfunction","cognitive dysfunction","computer-based cognitive rehabilitation","2025-02-19",{"date":120,"type":121},"2025-02-20","ACTUAL",{"date":123,"type":121},"2020-06-01",{"date":125,"type":100},"2026-06-30",{"name":5,"class":6},2]