[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618920":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":27,"centralContacts":27,"locations":28,"responsibleParty":48,"collaborators":27,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":27,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":72,"overallStatus":31,"whyStopped":27,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University Hospital, Montpellier","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with borderline personality","EXPERIMENTAL","Patients with borderline personality disorder without bipolar disorder",[13],"Other: Relationship-use questionnaire",{"label":15,"type":10,"description":16,"interventionNames":17},"Patients with bipolar disorder","patients with bipolar disorder without borderline personality disorder",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Healthy controls","Healthy controls (i.e. without psychiatric disorders), from the general population",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":27},"Relationship-use questionnaire","Questionnaire adapted from the 'Substance Use Disorders' section of the DSM-5: Disorder related to the use of close relationships",[19,15,9],null,[29],{"facility":30,"status":31,"city":32,"state":27,"zip":33,"country":34,"countryCode":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"CHU Montpellier","RECRUITING","Montpellier","34000","France","FR",{"type":37,"coordinates":38},"Point",[39,40],3.87635,43.61093,{"lat":40,"lon":39},[43],{"name":44,"role":45,"phone":46,"phoneExt":27,"email":47},"DUCASSE Déborah","CONTACT","04 67 33 82 89","d-ducasse@chu-montpellier.fr",{"type":49,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100618920","conceptualizing-borderline-personality-disorder-as-a-relationship-use-disorder-100618920",false,"NCT07337889","Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder","TLUR","Inclusion Criteria:\n\n* General : aged 18-45\n* Specific :\n* Borderline personality disorder (BPD)assessed by SCID, without bipolar disorder\n* Bipolar disorder (assessed by SCID), without BPD (evaluated by SCID)\n* Healthy controls with no psychiatric disorders (screened by SCID).\n\nExclusion Criteria:\n\n* Psychotic disorders (evaluated by SCID)\n* lack of informed consent\n* Not affiliated with social security\n* Under judicial or administrative confinement or involuntary hospitalization\n* Protected by law (e.g., under guardianship)\n* Pregnancy or breastfeeding\n* Inability to understand, speak, or write in French\n* Inability to understand the study's purpose or methodology\n* Excluded from another study during the exclusion period\n* Participants who have received over €6000 in annual indemnities\n* For Bipolar Participants (without BPD) : Current moderate or severe depressive episode (BDI score \\> 18) or Current hypomanic\u002Fmanic episode (YMRS \\\u003C 12)",true,"ALL","18 Years","45 Years",{"count":62,"type":63},194,"ESTIMATED","INTERVENTIONAL",[66],"NA","This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a \"Relationship Use Disorder.\" The research proposes that BPD shares key features with behavioral addictions, specifically addiction to interpersonal relationships. The study builds upon previous findings suggesting that individuals with BPD experience intense emotional dysregulation, including negative self-perception, shame, and a compulsive need for external validation. This addiction to relationships, much like substance use disorders, is thought to contribute significantly to the difficulties faced by these individuals, including interpersonal conflicts, self-destructive behaviors, and emotional instability.\n\nThe study seeks to demonstrate that the relational difficulties central to BPD meet the diagnostic criteria for addiction as defined by the DSM-5. It will also explore how these relational struggles are mediated by dysfunctional self-perception and whether they are linked to behaviors such as compulsive sexual behaviors (CSBD) or suicidal tendencies. Additionally, the research will investigate the relationship between addiction to relationships and neurobiological factors, including endorphin levels, in individuals with BPD compared to those with bipolar disorder and healthy controls. The hypothesis is that individuals with BPD will exhibit higher levels of relationship addiction, with this addiction being tied to their perception of self-worth and emotional experiences in relationships.\n\nThis innovative approach aims to refine the understanding of BPD, reduce stigma, and improve treatment strategies by providing scientific evidence supporting the conceptualization of BPD as a \"Relationship Use Disorder.\"",[69,70,71],"Borderline Personality Disorder","Borderline Personality Disorder (BPD)","Bipolar Disorder (BD)",[73,74],"borderline personality disorder","relationship-use disorder","2026-06-18",{"date":77,"type":78},"2026-06-22","ACTUAL",{"date":80,"type":78},"2026-06-01",{"date":82,"type":63},"2028-08-01",{"name":5,"class":6},1]