[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100426946":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":30,"responsibleParty":54,"collaborators":19,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":60,"acronym":19,"eligibilityCriteria":61,"healthyVolunteers":58,"sex":62,"minAge":63,"maxAge":19,"enrollmentInfo":64,"targetDuration":19,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":77,"overallStatus":32,"whyStopped":19,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Dana-Farber Cancer Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"CONCURRENT LAPAROSCOPIC HYSTERECTOMY AND WEIGHT LOSS SURGERY","EXPERIMENTAL","Upon enrollment in the study at first appointment with gynecologic oncologist, referral to the BWH Center for Metabolic and Bariatric Surgery (CMBS).\n\n* Schedule a series of appointments with a bariatric surgeon, nutritionist and psychologist, which is part of the approval process for weight loss surgery.\n* Hysterectomy and weight loss surgery will then be scheduled on the same day within 8 weeks from first visit with the gynecologic oncologist for endometrial cancer or 12 weeks if you have endometrial pre-cancer.\n* Series of post-operative visits with the bariatric surgeon and gynecologic oncologic surgeon as well as the nutritionist and psychologist.",[13],"Other: CONCURRENT LAPAROSCOPIC HYSTERECTOMY AND WEIGHT LOSS SURGERY-Referral",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"CONCURRENT LAPAROSCOPIC HYSTERECTOMY AND WEIGHT LOSS SURGERY-Referral","See arm description",[9],null,[21],{"name":22,"affiliation":23,"role":24},"Colleen Feltmate, MD","Brigham and Women's Hospital","PRINCIPAL_INVESTIGATOR",[26],{"name":22,"role":27,"phone":28,"phoneExt":19,"email":29},"CONTACT","617-732-8840","cfeltmate@bwh.harvard.edu",[31,47],{"facility":23,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-71.05977,42.35843,{"lat":42,"lon":41},[45,46],{"name":22,"role":27,"phone":19,"phoneExt":19,"email":19},{"name":22,"role":24,"phone":19,"phoneExt":19,"email":19},{"facility":5,"status":32,"city":33,"state":34,"zip":48,"country":36,"countryCode":37,"cosmosGeoPoint":49,"geoPoint":51,"contacts":52},"02215",{"type":39,"coordinates":50},[41,42],{"lat":42,"lon":41},[53],{"name":22,"role":24,"phone":19,"phoneExt":19,"email":19},{"type":24,"investigatorFullName":22,"investigatorTitle":55,"investigatorAffiliation":23,"oldNameTitle":19,"oldOrganization":19},"Principal Investigator","100426946","concurrent-laparoscopic-hysterectomy-and-weight-loss-surgery-in-obese-patients-with-endometrial-carcinoma-or-endometrial-intraepithelial-neoplasia-100426946",false,"NCT04839614","Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia","Inclusion Criteria:\n\n* Female adults at least 18 years of age\n* A BMI of 35-39.99 and 1 or more severe obesity-related co-morbidities\n\n  --including T2D,112 hypertension, hyperlipidemia, obstructive sleep apnea (OSA), obesity-hypoventilation syndrome (OHS), Pickwickian syndrome (a combination of OSA and OHS), nonalcoholic 4 fatty liver disease (NAFLD) or nonalcoholic steatohepatitis (NASH), pseudotumor cerebri, gastroesophageal reflux disease (GERD), asthma, venous stasis disease, severe urinary incontinence, debilitating arthritis, or considerably impaired quality of life) OR a BMI ≥ 40\n* Tissue diagnosis (usually endometrial biopsy) of grade 1 endometrial carcinoma or EIN.\n\nExclusion Criteria:\n\n* Younger than 18 years old\n* BMI \\\u003C 35\n* Without a tissue diagnosis, or with a grade 2 or greater endometrial cancer tissue diagnosis\n* Pregnant participants will be excluded from this study.\n* Patients with contraindications to bariatric surgery will also be excluded.\n\n  --This includes active smokers, prior bariatric surgery, active substance abuse, recent suicide attempt, bulimia nervosa, large abdominal hernias, or poorly controlled psychiatric illness\n* include inability to read an English informed consent form, and unwillingness to provide informed consent.","FEMALE","18 Years",{"count":65,"type":66},30,"ESTIMATED","INTERVENTIONAL",[69],"NA","To assess the feasibility of an expedited referral process for the obese endometrial cancer or EIN patient from her gynecologic oncologist to the Brigham Center for Metabolic and Bariatric Surgery (CMBS) in order to undergo concurrent weight loss surgery and hysterectomy within 8 weeks of first appointment with a gynecologic oncologist (or 12 weeks for EIN patients).",[72,73,74,75,76],"Endometrial Carcinoma","Obesity","EIN","Endometrial Intraepithelial Neoplasia","Endometrial Cancer Stage I",[72,73,74,75,76,78,79],"Weight Loss Surgery","Bariatric Surgery","2025-08-04",{"date":82,"type":83},"2025-08-07","ACTUAL",{"date":85,"type":83},"2021-08-01",{"date":87,"type":66},"2028-06-30",{"name":5,"class":6},2]