[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100630846":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":38,"locations":48,"responsibleParty":112,"collaborators":11,"id":115,"slug":116,"hasResults":117,"nctId":118,"briefTitle":119,"officialTitle":120,"acronym":121,"eligibilityCriteria":122,"healthyVolunteers":117,"sex":123,"minAge":124,"maxAge":125,"enrollmentInfo":126,"targetDuration":11,"studyType":129,"phases":130,"briefSummary":132,"conditions":133,"keywords":137,"overallStatus":143,"whyStopped":11,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":153},{"fullName":5,"class":6},"Rigshospitalet, Denmark","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"LBB\u002FHIS-CRT group","EXPERIMENTAL",null,[13],"Procedure: HIS or LBBB -CRT",{"label":15,"type":10,"description":11,"interventionNames":16},"BiV-CRT group",[17],"Procedure: Conventional BiV-CRT",[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"PROCEDURE","HIS or LBBB -CRT","HIs pacing og LBB pacing at the implanteres discretion",[9],{"type":20,"name":25,"description":26,"armGroupLabels":27,"otherNames":11},"Conventional BiV-CRT","An LV-lead in a side-branch of the coronary sinus",[15],[29,33,35],{"name":30,"affiliation":31,"role":32},"Niels Risum Risum, MD, PhD","Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":31,"role":32},"michael vinther, MD, PhD",{"name":36,"affiliation":31,"role":37},"Berit Philbert","STUDY_CHAIR",[39,44],{"name":40,"role":41,"phone":42,"phoneExt":11,"email":43},"Niels Risum, MD, PhD","CONTACT","0045 35456995","niels.risum.01@regionh.dk",{"name":45,"role":41,"phone":46,"phoneExt":11,"email":47},"Michael Vinther, MD, PhD","0045 35456994","michael.vinther@regionh.dk",[49,66,81,97],{"facility":50,"status":11,"city":51,"state":11,"zip":52,"country":53,"countryCode":54,"cosmosGeoPoint":55,"geoPoint":60,"contacts":61},"Dept. of Cardiology, Aarhus University Hospital, Aarhus","Aarhus","8200","Denmark","DK",{"type":56,"coordinates":57},"Point",[58,59],10.21076,56.15674,{"lat":59,"lon":58},[62],{"name":63,"role":41,"phone":64,"phoneExt":11,"email":65},"Jens Kristensen, MD, PhD","0045 29410644","jens.kristensen@auh.rm.dk",{"facility":67,"status":11,"city":68,"state":11,"zip":69,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":76,"contacts":77},"Dept of Cardiology, Meilahti Hospital, Helsinki","Helsinki","00290","Finland","FI",{"type":56,"coordinates":73},[74,75],24.93545,60.16952,{"lat":75,"lon":74},[78],{"name":79,"role":41,"phone":11,"phoneExt":11,"email":80},"Jarkko Karvonen Karvonen","jarkko.karvonen@hus.fi",{"facility":82,"status":11,"city":83,"state":11,"zip":84,"country":85,"countryCode":86,"cosmosGeoPoint":87,"geoPoint":91,"contacts":92},"Haukeland Universitetssykehus","Bergen","5009","Norway","NO",{"type":56,"coordinates":88},[89,90],5.32415,60.39299,{"lat":90,"lon":89},[93],{"name":94,"role":41,"phone":95,"phoneExt":11,"email":96},"Torbjørn Lunde","0047 xxxxxxxx","torbjorn.lunde@gmail.com",{"facility":98,"status":11,"city":99,"state":11,"zip":11,"country":100,"countryCode":101,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Sahlgrenska University Hospital","Gothenburg","Sweden","SE",{"type":56,"coordinates":103},[104,105],11.96679,57.70716,{"lat":105,"lon":104},[108],{"name":109,"role":41,"phone":110,"phoneExt":11,"email":111},"Amar Taha","0046 313427551","Amar.taha@vregionh.se",{"type":32,"investigatorFullName":113,"investigatorTitle":114,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Niels Risum","Md, PhD, Consultant cardiologist and electrophsiologist,","100630846","conduction-system-pacing-vs-biventricular-pacing-for-cardiac-resynchronization-therapy-100630846",false,"NCT07492979","Conduction System Pacing vs. Biventricular Pacing for Cardiac Resynchronization Therapy","Nordic-CSP - a Randomized Nordic Study - Is Conduction System Pacing Superior Compared to Conventional BIV-CRT in Reducing the Death or Heart Failure-related Hospitalization in Patients With Heart Failure and Bundle Branch Block?","Nordic-CSP","Inclusion Criteria:\n\n* ≥18 years of age,\n* LVEF ≤ 35%,\n* NYHA Class II-IV (IV only outpatients),\n* optimized in medical treatment (OMT)\n\nAND one of the following:\n\n. LBBB according to AHA\u002FACC\u002FHRS Scientific Statement from 2009 and ≥130ms or\n\n* LBBB-like intraventricular conduction delay (IVCD) \\> 150ms or RV paced QRS and indication for upgrade to CRT (\\> 40% RV pacing) OR\n* ≥18 years of age,\n* LVEF ≤ 40 %\n* pacing indicated by AV-block and, thus, expected large percentage of ventricular pacing.\n\nExclusion Criteria:\n\n* recent acute myocardial infarction (AMI)\n* coronary artery bypass graft (CABG) (\\\u003C3 months)\n* life expectancy \\\u003C2 years, patients in hemodialysis\n* treatment with a cardiac implantable electronic device (CIED) is contraindicated.\n* Patients are excluded with regards to the MRI sub study if eGFR \\> 35 ml\u002Fmin, in case or contrast allergy or certain metal implants.","ALL","18 Years","99 Years",{"count":127,"type":128},1100,"ESTIMATED","INTERVENTIONAL",[131],"NA","The NORDIC-CSP trial is an investigator-initiated, blinded, nordic RCT aimed at evaluating whether using direct pacing of the HIS bundle (HIS)-pacing or left bundle branch (LBB) pacing is superior to conventional biventricular pacing in reducing the incidence of the composite endpoint of death and non-planned HF hospitalization. The study will be conducted in the 4 CRT-centres in Denmark and 6-8 centres from countries Sweden, Norway and Finland.",[134,135,136],"Cardiac Resynchronisation Therapy (CRT)","Heart Failure","Conduction System Pacing",[121,138,139,140,141,142],"conduction system pacing","His-pacing","LBB-pacing","Biventricular pacing","Cardiac Resynchronization Therapy","NOT_YET_RECRUITING","2026-03-20",{"date":146,"type":147},"2026-03-25","ACTUAL",{"date":149,"type":128},"2026-03-01",{"date":151,"type":128},"2031-07-01",{"name":5,"class":6},4]