[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620488":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":24,"responsibleParty":35,"collaborators":24,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":39,"sex":45,"minAge":46,"maxAge":24,"enrollmentInfo":47,"targetDuration":24,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":62,"whyStopped":24,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":24},{"fullName":5,"class":6},"McMaster University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Conservative Care","ACTIVE_COMPARATOR","Standard of care intervention",[13],"Other: Conservative Care",{"label":15,"type":10,"description":11,"interventionNames":16},"Surgical Decompression",[17],"Procedure: Decompression Surgery",[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Decompression Surgery","Surgical decompression of the cervical spine",[15],null,{"type":6,"name":9,"description":26,"armGroupLabels":27,"otherNames":24},"Conservative care Program for cervical myelopathy",[9],[29],{"name":30,"role":31,"phone":32,"phoneExt":33,"email":34},"Sydney Research Coordinator","CONTACT","905-521-2100","44848","maclesd@mcmaster.ca",{"type":36,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100620488","conservative-care-versus-decompression-trial-for-degenerative-cervical-myelopathy-pilot-100620488",false,"NCT07358273","Conservative Care Versus Decompression Trial for Degenerative Cervical Myelopathy Pilot","Conservative Care Versus Decompression Trial for Degenerative Cervical Myelopathy Pilot: A Multicenter Randomized Controlled Feasibility Trial","CADET-DCM","Inclusion Criteria:\n\n* 18 years of age or older\n* Show evidence of spinal cord compression between C2 and T1 on MRI or CT myelography conducted within 2 years of enrollment\n* Present with mild DCM defined as a score of 15-17 on the modified Japanese Orthopaedic Association (mJOA) score\n\nExclusion Criteria:\n\n* Clinical suspicion that myelopathic symptoms are exacerbated or caused by another neurologic condition (i.e. amyotrophic lateral sclerosis, multiple sclerosis, syringomyelia, peripheral neuropathy)\n* Demonstrate ossification of the posterior longitudinal ligament (OPLL)\n* Previous cervical spine surgery\n* Report known or suspected tandem symptomatic thoracic or lumbar spinal stenosis\n* Present with an acute traumatic spinal cord injury (i.e., central cord syndrome)\n* Have a prior history of an acute spinal cord injury\n* Have spinal cord compression due to an infectious or oncologic process\n* Inflammatory arthritis\n* Significant active health-related comorbidity (ASA Class IV or higher)\n* English language ability insufficient to complete outcome questionnaires","ALL","18 Years",{"count":48,"type":49},56,"ESTIMATED","INTERVENTIONAL",[52],"NA","This study is a pilot randomized clinical trial designed to test whether it is feasible to conduct a larger study comparing two standard treatments for mild degenerative cervical myelopathy (DCM).\n\nThe main questions it aims to answer are:\n\n* Can enough participants be recruited and successfully complete follow-up assessments?\n* Will participants adhere to their assigned treatment?\n\nResearchers will compare two groups:\n\n* Surgical group: Participants receive decompressive spine surgery (with or without fusion).\n* Conservative care group: Participants follow a structured program that includes education, fall prevention strategies, and tailored exercises.\n\nParticipants will:\n\n* Complete baseline and follow-up assessments at 6 weeks, 6 months, and 12 months.\n* In the surgical group: undergo surgery within 12 weeks of randomization and receive standard post-operative care.\n* In the conservative care group: follow a 6-week progressive exercise program and continue self-management strategies.\n* Complete a monthly online symptom monitoring questionnaire",[55],"Degenerative Cervical Myelopathy",[57,58,59,60,61],"myelopathy","spinal cord diseases","surgery","conservative care","spine","NOT_YET_RECRUITING","2026-01-13",{"date":65,"type":66},"2026-01-22","ACTUAL",{"date":68,"type":49},"2026-02",{"date":70,"type":49},"2027-06",{"name":5,"class":6}]