[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100460099":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":30,"collaborators":7,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":36,"acronym":7,"eligibilityCriteria":37,"healthyVolunteers":34,"sex":38,"minAge":39,"maxAge":40,"enrollmentInfo":41,"targetDuration":44,"studyType":45,"phases":7,"briefSummary":46,"conditions":47,"keywords":7,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":58},{"fullName":5,"class":6},"Tel-Aviv Sourasky Medical Center","OTHER_GOV",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Ofer Havakuk, MD","CONTACT","+97236974250","oferh@tlvmc.gov.il",[15],{"facility":16,"status":17,"city":18,"state":7,"zip":19,"country":20,"countryCode":21,"cosmosGeoPoint":22,"geoPoint":27,"contacts":28},"Tel Aviv Sourasky Medical Center","RECRUITING","Tel Aviv","6423906","Israel","IL",{"type":23,"coordinates":24},"Point",[25,26],34.78057,32.08088,{"lat":26,"lon":25},[29],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"type":31,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100460099","conservative-management-of-left-ventricular-assist-device-candidates-100460099",false,"NCT05271214","Conservative Management of Left Ventricular Assist Device Candidates","Inclusion Criteria:\n\n\\- left ventricular ejection fraction \\\u003C35%. New York Heart Association Class III or IV. Brain natriuretic peptide levels \\> 450pg\u002Fml. Heart failure hospitalization in the past 6 months. Maximal oxygen consumption \\\u003C 12 ml\u002Fkg\u002Fmin. Intolerant to conventional heart failure therapy.\n\nExclusion Criteria:\n\n\\- Special populations - pregnant, unable to give informed consent. Advanced liver disease (Child Pugh class B or C). Advanced kidney disease (eGFR\\\u003C30ml\u002Fmin). Severe pulmonary disease. Severe peripheral vascular disease. Active malignancy.","ALL","18 Years","80 Years",{"count":42,"type":43},100,"ESTIMATED","5 Years","OBSERVATIONAL","Left ventricular assist device (LVAD) candidates will be comprehensively evaluated at our center, including clinical evaluation, echocardiography, right heart catheterization, cardiopulmonary exercise test and laboratory exams. following this evaluation, patients will be treated with inotropes, diuretics, uptitrated neurohormonal therapy. vitamin and iron deficiencies will be corrected and the patients will be referred for coronary interventions and cardiac resynchronization therapy appropriately. The need for LVAD implantation will be reevaluated according to the patient's clinical condition, echocardiography and laboratory findings.",[48],"Advanced Heart Failure","2022-02-26",{"date":51,"type":52},"2022-03-08","ACTUAL",{"date":54,"type":52},"2018-01-01",{"date":56,"type":43},"2028-01",{"name":5,"class":6},1]