[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100478842":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":47,"collaborators":19,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":19,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":19,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":19,"overallStatus":32,"whyStopped":19,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Grade 2-5 CI Therapy + Sensory Components","EXPERIMENTAL","All participants will receive CI Therapy + Sensory Components administered over the specific time frame of 2-3 weeks.",[13],"Behavioral: Grade 2-5 CI Therapy + Sensory Components",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"BEHAVIORAL","All participants will receive CI Therapy + Sensory Components over a 2-3 weeks time frame. The treatment intervention will apply all CI Therapy treatment components to include: 1) a behavioral set of techniques called the Transfer Package (TP) to promote carry-over of skills that were gained in the laboratory into the participant's life situation, 2) the use of motor training called shaping to make progress in small approximations 3) the use by the participant of a mitt on the less-affected hand to encourage use of the more-affected hand and 4) home skills and home work will be provided each day for at least 30 minutes. Sensory component training strategies will be added to stimulate sensory input through the more-affected arm an dhand as well as to train sensory discrimination skills.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"David Morris, PhD","STUDY_CHAIR",[25],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Mary Bowman, BS OT","CONTACT","2059340069","mbowman@uab.edu",[31],{"facility":5,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Birmingham","Alabama","35233","United States","US",{"type":39,"coordinates":40},"Point",[41,42],-86.80249,33.52066,{"lat":42,"lon":41},[45],{"name":46,"role":27,"phone":28,"phoneExt":19,"email":29},"Mary H Bowman, BS OT",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"PRINCIPAL_INVESTIGATOR","Mary H Bowman","Assistant Professor","100478842","constraint-induced-movement-therapy-plus-sensory-components-after-stroke-100478842",false,"NCT05515237","Constraint-Induced Movement Therapy Plus Sensory Components After Stroke","Constraint-Induced Movement Therapy Plus Sensory Components for Adults With Mild-to-Severe Arm and Hand Impairment After Stroke","Inclusion Criteria:\n\n* At least 6 months post stroke\n* The ability to demonstrate the minimum UE active movement criteria of shoulder ≥ 30 toward flexion or abduction, initiate movement at the elbow for flexion and extension, and initiate movement at the wrist, fingers, or thumb.\n* Mean score of \\\u003C2.5 on the Motor Activity Log\u002F G4\u002F5 Motor Activity Log indicating the participant's use of the more-affected UE.\n\nExclusion Criteria:\n\n* Score\\\u003C 24 on the Mini Mental State Exam\n* Inability to answer the MAL\u002F G4\u002F5 MAL questions and\u002For provide informed consent\n* The inability to come in to the laboratory setting for treatment.","ALL","18 Years","89 Years",{"count":62,"type":63},15,"ESTIMATED","INTERVENTIONAL",[66],"NA","Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following strategies utilized: behavioral strategies are implemented to improve the use of the more- affected limb in life situation called a Transfer Package (TP), motor training using a technique called shaping to make progress in successive approximations, repetitive, task oriented training, and strategies to encourage or constrain participants to use the more-affected extremity including restraint of the less-affected arm in the upper extremity (UE) protocol. Numerous studies examining the application of CI therapy with UE rehabilitation after stroke have demonstrated strong evidence for improving the amount of use and the quality of the more-affected UE functional use in the participant's daily life situation.\n\nCI Therapy studies with adults, to date, have explored intensive treatment for participants with a range from mild-to-severe motor impairment following stroke with noted motor deficits and limited use of the more-affected arm and hand in everyday activities. Each CI Therapy protocol was designed for the level of impairment demonstrated by participants recruited for the study. However, often following stroke, patients not only have motor deficits but somatosensory impairments as well. The somatosensory issues have not, as yet, been systematically measured and trained in CI Therapy protocols with adults and represent an understudied area of stroke recovery. We hypothesize that participants with mild-to-severe motor impairment and UE functional use deficits can benefit from CI therapy protocols that include somatosensory measurement and training components substituted for portions of motor training without loss in outcome measure gains. Further, we hypothesize that adults can improve somatosensory outcomes as a result of a combined CI therapy plus somatosensory component protocol.",[69,70,71],"CVA (Cerebrovascular Accident)","Stroke","Upper Extremity Paresis","2026-04-08",{"date":74,"type":75},"2026-04-13","ACTUAL",{"date":77,"type":75},"2023-03-30",{"date":79,"type":63},"2027-06",{"name":5,"class":6},1]