[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627699":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":26,"locations":26,"responsibleParty":31,"collaborators":26,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":37,"acronym":26,"eligibilityCriteria":38,"healthyVolunteers":35,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":26,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":54,"whyStopped":26,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":26},{"fullName":5,"class":6},"Peking University Third Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Experimental Arm","EXPERIMENTAL","Enrolled into a comprehensive health-management platform for cardiorenal metabolic syndrome and received integrated management for 2 years.",[13],"Behavioral: Comprehensive Health Management Platform",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Arm","ACTIVE_COMPARATOR","The control group receives routine post-examination follow-up and health management provided by the health check-up center.",[19],"Other: Post-examination follow-up management",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Comprehensive Health Management Platform","The health-management programme comprises:\n\n* Screening: collection of demographic data, medical and personal history, physical examination (blood pressure, heart rate, etc.), laboratory tests (inflammatory markers, lipids, glucose, renal and liver function), exercise habits, nutritional status, body-composition analysis, and physical-fitness tests (reaction time, grip strength, vertical jump, one-leg stance with eyes closed, back strength, sit-and-reach, 1-min sit-ups, 1-min push-ups, cardiopulmonary exercise test).\n\n  * Assessment: CKM risk stratification based on the above. ③ Intervention: individualised exercise, dietary and pharmacological prescriptions.\n\n    * Follow-up: ongoing monitoring of clinical indices, exercise, diet and medication adherence by a physician-health-manager team.",[9],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Post-examination follow-up management","Post-examination report interpretation service and telephone follow-up for patients with abnormal findings.",[15],{"type":32,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100627699","construction-of-a-comprehensive-health-management-platform-for-patients-with-cardiovascular-kidney-metabolic-syndrome-100627699",false,"NCT07452029","Construction of a Comprehensive Health Management Platform for Patients With Cardiovascular-Kidney-Metabolic Syndrome","Inclusion Criteria:\n\n* CKM stage 0-2 as defined by the American Heart Association CKM diagnostic guidelines\n* Age 18-75 years\n* Able to use a smartphone and wearable activity tracker\n* Willing to sign informed consent and attend scheduled follow-up visits\n\nExclusion Criteria:\n\n* CKM stage 3-4\n* Acute or critically ill conditions requiring hospitalization\n* Malignant tumors or any active cancer under treatment","ALL","18 Years","75 Years",{"count":43,"type":44},150,"ESTIMATED","INTERVENTIONAL",[47],"NA","Cardiovascular-Kidney-Metabolic (CKM) syndrome underscores the pathophysiologic interplay among metabolic risk factors, chronic kidney disease (CKD) and the cardiovascular system. This crosstalk precipitates multi-organ dysfunction, increases adverse cardiovascular events, and imposes heavy familial and socioeconomic burdens. Building a health-management platform within research wards is therefore urgent. Such a platform is the pivotal venue for assessment, monitoring, intervention and follow-up in continuous care.\n\nLeveraging the existing health-management system of the Health Screening Center at Peking University Third Hospital, the investigators will develop a comprehensive CKM platform that integrates systemic inflammatory biomarkers, cardiovascular early-warning algorithms, and personalized diet-and-exercise prescriptions. The system will provide cyclic management encompassing evaluation, guidance, monitoring, feedback and longitudinal follow-up.\n\nA randomized controlled trial with two-year prospective follow-up will enroll patients at CKM stages 0-2 to evaluate clinical improvement, quality of life, dietary behavior and physical activity after platform enrollment. The project will enable early identification of high-risk individuals, deliver precision management, maximize data utility, and offer a novel research-ward model that addresses mobile-health pain points and closes the CKM care loop.",[50],"Cardiovascular-Kidney-Metabolic Syndrome",[23,52,53,50],"Mobile Health","Early identification","NOT_YET_RECRUITING","2026-03-01",{"date":57,"type":58},"2026-03-05","ACTUAL",{"date":60,"type":44},"2026-03",{"date":62,"type":44},"2027-12",{"name":5,"class":6}]