[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100586206":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":36,"locations":44,"responsibleParty":144,"collaborators":147,"id":149,"slug":150,"hasResults":151,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":18,"eligibilityCriteria":155,"healthyVolunteers":151,"sex":156,"minAge":157,"maxAge":18,"enrollmentInfo":158,"targetDuration":18,"studyType":161,"phases":162,"briefSummary":164,"conditions":165,"keywords":167,"overallStatus":47,"whyStopped":18,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":179},{"fullName":5,"class":6},"Université NAZI BONI","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"CPAP group","EXPERIMENTAL","Continuous CPAP (with Boussignac valve) for the first 6-12 hours, then alternating with standard oxygen therapy. CPAP pressure= 7.5 cmH2O (25L\u002Fmin) then variations of +\u002F- 2.5 cmH20 according to clinical response and tolerance until weaning from oxygen or presence of intubation criteria",[13],"Other: CPAP",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard group","NO_INTERVENTION","Oxygen therapy as required using, simple face masks or high concentration face masks until there are criteria for intubation, or withdrawal from oxygen.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"CPAP","Continuous Positive Airway Pressure (CPAP) with Boussignac valve",[9],[25,29,33],{"name":26,"affiliation":27,"role":28},"Armand Mekontso-dessap, professor","Assistance Publique - Hôpitaux de Paris","STUDY_CHAIR",{"name":30,"affiliation":31,"role":32},"Ismael Guibla, doctor","University Hospital Souro Sanou, Burkina Faso","PRINCIPAL_INVESTIGATOR",{"name":34,"affiliation":31,"role":35},"Ibrahim Alain Traore, professor","STUDY_DIRECTOR",[37,41],{"name":30,"role":38,"phone":39,"phoneExt":18,"email":40},"CONTACT","+22676135113","ismaelguibla@gmail.com",{"name":34,"role":38,"phone":42,"phoneExt":18,"email":43},"+22671457580","itraore80@gmail.com",[45,72,97,126],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Centre Hospitalier Universitaire Souro Sanou","RECRUITING","Bobo-Dioulasso","Houet","01 BP 676","Burkina Faso","BF",{"type":54,"coordinates":55},"Point",[56,57],-4.29489,11.18064,{"lat":57,"lon":56},[60,64,65,68,70],{"name":61,"role":38,"phone":62,"phoneExt":18,"email":63},"Adama Decard Sawadogo, doctor","+22667337419","sadeca@gmail.com",{"name":30,"role":38,"phone":39,"phoneExt":18,"email":40},{"name":66,"role":67,"phone":18,"phoneExt":18,"email":18},"Jean Noel Savadogo, doctor","SUB_INVESTIGATOR",{"name":69,"role":32,"phone":18,"phoneExt":18,"email":18},"Sansan Armand Kambou, doctor",{"name":71,"role":67,"phone":18,"phoneExt":18,"email":18},"Ibrahim Alain Traore, Professor",{"facility":73,"status":74,"city":75,"state":76,"zip":77,"country":51,"countryCode":52,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"CHU Yalgado Ouedraogo","NOT_YET_RECRUITING","Ouagadougou","Kadiogo","03 BP 702250311655",{"type":54,"coordinates":79},[80,81],-1.53388,12.36566,{"lat":81,"lon":80},[84,88,92,94,96],{"name":85,"role":38,"phone":86,"phoneExt":18,"email":87},"Martin Lankoande, doctor","+22670606447","m.lansongui@gmail.com",{"name":89,"role":38,"phone":90,"phoneExt":18,"email":91},"Papougnezambo Bonkoungou, doctor","+22670415444","zambonkoungou@yahoo.fr",{"name":93,"role":67,"phone":18,"phoneExt":18,"email":18},"Souphiane Abou, doctor",{"name":95,"role":67,"phone":18,"phoneExt":18,"email":18},"Papougnezambo Bonkoungou, Professor",{"name":85,"role":32,"phone":18,"phoneExt":18,"email":18},{"facility":98,"status":74,"city":75,"state":76,"zip":99,"country":51,"countryCode":52,"cosmosGeoPoint":100,"geoPoint":102,"contacts":103},"CHU Tengandogo","03 BP 7067",{"type":54,"coordinates":101},[80,81],{"lat":81,"lon":80},[104,108,112,114,116,118,120,122,124],{"name":105,"role":38,"phone":106,"phoneExt":18,"email":107},"Imbe Ignace Yaro, doctor","+22670675148","yaroignace@gmail.com",{"name":109,"role":38,"phone":110,"phoneExt":18,"email":111},"Flavien Kabore, professor","+22670142327","kflavien72@yahoo.fr",{"name":113,"role":67,"phone":18,"phoneExt":18,"email":18},"Farid Pingwinde Belem, doctor",{"name":115,"role":67,"phone":18,"phoneExt":18,"email":18},"Fatou Fleur Sanou, doctor",{"name":117,"role":32,"phone":18,"phoneExt":18,"email":18},"Frida Djinkinde, doctor",{"name":119,"role":67,"phone":18,"phoneExt":18,"email":18},"Cheick Bougouma, doctor",{"name":121,"role":67,"phone":18,"phoneExt":18,"email":18},"Flavien Kabore, doctor",{"name":123,"role":67,"phone":18,"phoneExt":18,"email":18},"Ibrahim Kabre, doctor",{"name":125,"role":67,"phone":18,"phoneExt":18,"email":18},"Tewende Ouedraogo, doctor",{"facility":127,"status":74,"city":75,"state":76,"zip":128,"country":51,"countryCode":52,"cosmosGeoPoint":129,"geoPoint":131,"contacts":132},"CHU Bogodogo","14 BP 371",{"type":54,"coordinates":130},[80,81],{"lat":81,"lon":80},[133,137,141,142],{"name":134,"role":38,"phone":135,"phoneExt":18,"email":136},"Seif Idriss Salah Traore, doctor","+22670689698","seif_tis@yahoo.fr",{"name":138,"role":38,"phone":139,"phoneExt":18,"email":140},"Chamir Congo, doctor","+22673380662","congowendpanga20@gmail.com",{"name":138,"role":32,"phone":18,"phoneExt":18,"email":18},{"name":143,"role":67,"phone":18,"phoneExt":18,"email":18},"Jean Didier Sib, doctor",{"type":32,"investigatorFullName":145,"investigatorTitle":146,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Ismael Guibla","Clinical doctor",[148],{"name":27,"class":6},"100586206","continous-positive-airway-pressure-cpap-support-for-acute-hypoxemic-respiratory-failure-in-burkina-faso-100586206",false,"NCT06912360","Continous Positive Airway Pressure (CPAP) Support for Acute Hypoxemic Respiratory Failure in Burkina Faso","Use of (Continous Positive Airway Pressure) CPAP in the Management of Acute Hypoxemic Respiratory Failure","Inclusion Criteria:\n\nAll patients aged 18 years and older will be included in the study if they meet at least one of the following criteria :\n\n* Acute respiratory distress, defined as dyspnea respiratory rate ≥ 25 cycles\u002Fmin\n* Hypoxemia, defined as the need for more 6 liters of oxygen to maintain an oxygen saturation (SpO2) of ≥ 92%. The fraction of inspired oxygen (FiO2) will be estimated using the 3% rule.\n\nExclusion Criteria:\n\nPatients with any of the following criteria will not be included in the study:\n\n* Pregnant or breastfeeding women\n* Persons deprived of their liberty\n* Exacerbation of asthma, chronic obstructive pulmonary disease, or another chronic respiratory disease\n* Moderate to large amount of unilateral or bilateral undrained pleural effusion\n* Contraindication to CPAP: patient refusal, undrained pneumothorax, chest injury, repeated or large vomiting, upper gastrointestinal bleeding, craniofacial trauma, severe upper airway obstruction, or tetraplegia in the initial phase\n* Cardiac arrest, severe arrhythmias, shock requiring the use of vasopressors (norepinephrine, adrenaline, dopamine)\n* Altered level of consciousness (Glasgow Coma Scale score \\\u003C 13), repeated seizures, or status epilepticus\n* Medical decision to limit treatment: no intubation, no admission to intensive care\n* Refusal to participate in the study or participation in another interventional study on respiratory distress or acute respiratory failure.","ALL","18 Years",{"count":159,"type":160},240,"ESTIMATED","INTERVENTIONAL",[163],"NA","Acute respiratory failure (ARF) is a frequent medical emergency, involving high costs for health organizations and patients who often require intensive care and respiratory assistance. According to an international study, 61% of hypoxemic patients in intensive care receive invasive ventilation \\[3\\]. Invasive mechanical ventilation is often unavailable in low-income countries and non-invasive ventilatory supports such as continuous positive airway pressure (CPAP) and high-flow oxygen therapy (HFO) were very useful during the COVID-19 pandemic. They reduced the rate of intubation and ICU admissions. In addition, CPAP can be used without a ventilator, no electricity is required. So, it could be a support of choice in low-income countries.\n\nUsed of Boussignac-type CPAP could potentially reduce the recourse to intubation in patients with acute hypoxemic respiratory failure in a context where access to invasive ventilation remains very limited.",[166],"Acute Respiratory Failure",[21,168,169],"Acute hypoxemic respiratory failure","Africa","2025-07-23",{"date":172,"type":173},"2025-07-28","ACTUAL",{"date":175,"type":173},"2025-07-09",{"date":177,"type":160},"2026-02-20",{"name":5,"class":6},4]