[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100533980":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":27,"centralContacts":31,"locations":40,"responsibleParty":58,"collaborators":61,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":24,"enrollmentInfo":75,"targetDuration":24,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":88,"whyStopped":24,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"The University of Texas Health Science Center, Houston","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Blinded continuous vital sign monitoring","SHAM_COMPARATOR","Continuous ward monitoring with vital signs recorded but not available to patients, clinicians, or investigators.",[13],"Device: Blinded continuous vital sign monitoring",{"label":15,"type":16,"description":17,"interventionNames":18},"Unblinded continuous vital sign monitoring","EXPERIMENTAL","Continuous ward monitoring with vital signs available to clinicians and investigators.",[19],"Device: Unblinded continuous vital sign monitoring",[21,25],{"type":22,"name":9,"description":11,"armGroupLabels":23,"otherNames":24},"DEVICE",[9],null,{"type":22,"name":15,"description":17,"armGroupLabels":26,"otherNames":24},[15],[28],{"name":29,"affiliation":5,"role":30},"Daniel Sessler, MD","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":24,"email":36},"Valerie L Anderson, BS","CONTACT","(713) 500-4383","Valerie.L.Anderson@uth.tmc.edu",{"name":29,"role":34,"phone":38,"phoneExt":24,"email":39},"713-500-3062","Daniel.Sessler@uth.tmc.edu",[41],{"facility":42,"status":24,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"The University of Texas Health Science Center at Houston","Houston","Texas","77030","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-95.36327,29.76328,{"lat":52,"lon":51},[55,56],{"name":33,"role":34,"phone":35,"phoneExt":24,"email":36},{"name":57,"role":30,"phone":24,"phoneExt":24,"email":24},"Daniel I Sessler, M.D.",{"type":30,"investigatorFullName":59,"investigatorTitle":60,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Daniel Sessler","Professor and Vice President for Clinical and Outcomes Research",[62],{"name":63,"class":64},"Masimo Corporation","INDUSTRY","100533980","continuous-versus-intermittent-ward-monitoring-100533980",false,"NCT06232876","Continuous Versus Intermittent Ward Monitoring","Continuous Versus Intermittent Ward Monitoring on Vital Sign Abnormalities, Clinical Interventions, and Serious Complications: the CONSTANT Trial","CONSTANT","Inclusion Criteria:\n\n1. Are admitted to one of the wards equipped with the Masimo Radius PPG and Rad-97 monitors;\n2. Are ≥18 years old;\n3. Are designated American Society of Anesthesiologists physical status 1-4;\n4. Had major noncardiac surgery lasting at least 1.5 hours;\n5. Are expected to remain hospitalized at least two postoperative nights;\n6. Had general anesthesia with or without neuraxial anesthesia.\n\nExclusion Criteria:\n\n1. Have language, vision, or hearing impairments that may compromise continuous monitoring;\n2. Are designated Do Not Resuscitate, hospice, or receiving end of life care;\n3. Have previously participated in the study.","ALL","18 Years",{"count":76,"type":77},492,"ESTIMATED","INTERVENTIONAL",[80],"NA","The investigators will randomize adults having major non-cardiac inpatient surgery to blinded versus unblinded continuous postoperative vital sign monitoring (saturation, ventilation, and heart rate). The investigators will use a wearable, untethered, and battery-powered sensor (Masimo Radius PPG, Masimo, Irvine, CA) that wirelessly connects to a Masimo monitor and continuously records saturation, ventilation, and pulse rate.\n\nThe primary outcome will be areas-exceeding-thresholds for desaturation (\\\u003C85%), bradypnea (\\\u003C7 breaths\u002Fmin), tachypnea (\\>30 breaths\u002Fmin), tachycardia (heart rate \\>130 beats\u002Fmin), and bradycardia (heart rate \\\u003C45 beats\u002Fmin). These exposure thresholds represent a balance between events that are clinically meaningful and excessive alarms that will discourage clinician participation. The investigators expect about 1 alert per patient per day with these thresholds, with most being considered informative or actionable by nurses. In unblinded patients, clinician alerts will be activated at these thresholds.",[83],"Surgery",[85,86,83,87],"monitoring","Vital signs","Postoperative","NOT_YET_RECRUITING","2026-05-24",{"date":91,"type":92},"2026-05-28","ACTUAL",{"date":94,"type":77},"2026-06-01",{"date":96,"type":77},"2029-03-01",{"name":5,"class":6},1]