[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622551":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":28,"centralContacts":32,"locations":42,"responsibleParty":60,"collaborators":25,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":25,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":86,"overallStatus":45,"whyStopped":25,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Universitätsklinikum Hamburg-Eppendorf","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Blinded continuous vital sign monitoring","SHAM_COMPARATOR","Continuous ward monitoring with vital signs recorded but not available to patients, clinicians, or investigators.",[13],"Device: Blinded continuous vital sign monitoring",{"label":15,"type":16,"description":17,"interventionNames":18},"Unblinded continuous vital sign monitoring","EXPERIMENTAL","Continuous ward monitoring with vital signs available to investigators.",[19],"Device: Unblinded continuous vital sign monitoring",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Continuous ward monitoring with vital signs available to investigators. Oxygen saturation, blood pressure (intermittent in intervals of 60 minutes), heart rate, and respiratory rate will be continuously measured and streamed to the investigators (specifically, to a central monitor). The investigators will alert nurses or physicians when SpO2 is \\\u003C85% for ≥2 minutes, respiratory rate is \\\u003C7\u002Fmin or \\>30\u002Fmin for ≥2 minutes, MAP is \\\u003C60 mmHg, or heart rate is \\\u003C45 bpm or \\>130 bpm for ≥2 minutes, or in case of apnea for ≥1 minute - supplemented by clinical judgement and the complete electronic record. Investigators will alert clinicians when concerning patterns are identified, whether or not alerts have been triggered. Clinicians will determine if response is necessary and what interventions might be appropriate.",[15],null,{"type":22,"name":9,"description":11,"armGroupLabels":27,"otherNames":25},[9],[29],{"name":30,"affiliation":5,"role":31},"Bernd Saugel, MD","PRINCIPAL_INVESTIGATOR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":25,"email":37},"Kristen K Thomsen, MD","CONTACT","+4940741070215","kr.thomsen@uke.de",{"name":39,"role":35,"phone":40,"phoneExt":25,"email":41},"Simon Stemmler, MD","+4940741066077","s.stemmler@uke.de",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"University Medical Center Hamburg-Eppendorf","RECRUITING","Hamburg","Free and Hanseatic City of Hamburg","20251","Germany","DE",{"type":52,"coordinates":53},"Point",[54,55],9.99302,53.55073,{"lat":55,"lon":54},[58,59],{"name":34,"role":35,"phone":36,"phoneExt":25,"email":37},{"name":39,"role":35,"phone":40,"phoneExt":25,"email":41},{"type":31,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Kristen Thomsen","MD","100622551","continuous-vital-sign-monitoring-versus-routine-spot-checks-in-patients-after-non-cardiac-surgery-100622551",false,"NCT07385092","Continuous Vital Sign Monitoring Versus Routine Spot-checks in Patients After Non-cardiac Surgery","The Effect of Continuous Monitoring Versus Routine Spot-checks on Altered Vital Signs in Patients Recovering From Non-cardiac Surgery on Normal Wards: the \"COME ON, NOW!\" Trial","COME ON NOW","Inclusion Criteria:\n\nConsenting patients ≥45 years scheduled for elective non-cardiac (abdominal and thoracic) surgery with planned postoperative admission to a normal ward after an overnight stay in an advanced post-anesthesia care unit.\n\nExclusion Criteria:\n\n* Emergency surgery\n* Pregnancy\n* Impossibility to perform continuous monitoring with the Radius VSM sensor (Masimo, Irvine, CA)\n* Atrial fibrillation\n* Patients designated Do Not Resuscitate, or are receiving end-of-life care","ALL","45 Years",{"count":74,"type":75},264,"ESTIMATED","INTERVENTIONAL",[78],"NA","The \"COME ON, NOW!\" trial is a randomized, single-center trial in patients recovering from non-cardiac surgery on normal wards investigating whether continuous vital sign monitoring - compared to routine spot-checks by nurses - reduces the total duration of abnormal vital signs per hour during the first 48 hours after admission to the normal ward.",[81,82,83,84,85],"Vital Sign Monitoring","Post Operative Complications","Non-cardiac Surgery","RCT","Anesthesiology",[87,88,89,90,91,92,93,94],"continuous vital signs","vital signs","vital sign monitoring","post-operative care","anesthesiology","anesthesia","hypotension","post-operative complications","2026-02-27",{"date":97,"type":98},"2026-03-02","ACTUAL",{"date":100,"type":98},"2026-02-24",{"date":102,"type":75},"2026-12-31",{"name":5,"class":6},1]