[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622889":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":37,"locations":43,"responsibleParty":60,"collaborators":30,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":30,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":30,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":45,"whyStopped":30,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"University of Electronic Science and Technology of China","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Intermittent neurofeedback training","EXPERIMENTAL","Subjects in the intermittent neurofeedback training group are instructed to regulate their anterior insula activity based on the visual neurofeedback after each regulation block. This intermittent neurofeedback is based on averaged activity of the anterior insula during the regulation block.",[13],"Procedure: real-time fMRI neurofeedback training procedure",{"label":15,"type":16,"description":17,"interventionNames":18},"Intermittent sham control","SHAM_COMPARATOR","Subjects in the sham control group receive the same instruction but perform the regulation based on sham neurofeedback from the middle temporal gyrus (a controlled sham region).",[19],"Procedure: real-time fMRI sham-controlled neurofeedback training procedure",{"label":21,"type":10,"description":22,"interventionNames":23},"Continuous neurofeedback training","Subjects in the continuous neurofeedback training group are instructed to regulate their anterior insula activity based on the real-time visual neurofeedback during regulation blocks.",[13],[25,31,35],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"PROCEDURE","real-time fMRI neurofeedback training procedure","real-time fMRI neurofeedback training procedure running on the Turbo Brain voyager (TBV) 4.2 software (Brain Innovation, Maastricht, The Netherlands)",[9],null,{"type":26,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"real-time fMRI sham-controlled neurofeedback training procedure","real-time fMRI sham neurofeedback training procedure running on the Turbo Brain voyager (TBV) 4.2 software (Brain Innovation, Maastricht, The Netherlands)",[15],{"type":26,"name":27,"description":28,"armGroupLabels":36,"otherNames":30},[21],[38],{"name":39,"role":40,"phone":41,"phoneExt":30,"email":42},"Shuxia Yao, Dr","CONTACT","18111297596","yaoshuxia@uestc.edu.cn",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Chengdu","Sichuan","611731","China","CN",{"type":52,"coordinates":53},"Point",[54,55],104.06667,30.66667,{"lat":55,"lon":54},[58],{"name":59,"role":40,"phone":30,"phoneExt":30,"email":30},"Shuxia Yao",{"type":61,"investigatorFullName":59,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Associate Professor","100622889","continuous-vs-intermittent-rt-fmri-neurofeedback-training-of-the-anterior-insula-100622889",false,"NCT07389486","Continuous vs. Intermittent Rt-fMRI Neurofeedback Training of the Anterior Insula","A Comparative Study of Continuous vs. Intermittent Real-time fMRI Neurofeedback in Regulating Anterior Insula Activity","Inclusion Criteria:\n\nHealthy subjects without any past or present psychiatric or neurological disorders\n\nExclusion Criteria:\n\nHistory of brain injury medical or mental illness\n\nContraindication to MRI scanning (e.g., metal implants, claustrophobia or other --conditions that make them inappropriate for MRI scanning)",true,"ALL","18 Years","30 Years",{"count":75,"type":76},90,"ESTIMATED","INTERVENTIONAL",[79],"NA","The main aim of this study is to compare the efficacy of intermittent with continuous real-time functional magnetic resonance imaging (fMRI) neurofeedback on anterior insula regulation and associated behavioral changes.",[82],"Healthy",[84,85,86,87],"Real-time neurofeedback","Anterior insula","Feedback types","Interoceptive processing","2026-01-28",{"date":90,"type":91},"2026-02-05","ACTUAL",{"date":88,"type":91},{"date":94,"type":76},"2027-06-08",{"name":5,"class":6},1]