[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606352":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":36,"centralContacts":40,"locations":46,"responsibleParty":64,"collaborators":23,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":23,"eligibilityCriteria":73,"healthyVolunteers":69,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":23,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":48,"whyStopped":23,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"University Hospitals Cleveland Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Spinal Surgery Participants","EXPERIMENTAL","Participants scheduled for spinal surgery will have ESP block medications administered as per standard care along with contrast dye.",[13,14,15,16],"Drug: Ropivacaine (Epidural analgesia)","Drug: Dexmedetomidine","Drug: Iohexol","Procedure: QST Procedure",[18,24,27,31],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"DRUG","Ropivacaine (Epidural analgesia)","The block solution will consist of 1% ropivacaine 3 mg\u002FKg ideal body weight (IBW) mixed with dexmedetomidine 0.5 mcg\u002FKg IBW and diluted with 10 mL iohexol 300 mg\u002FmL and normal saline for a total volume of 40 mL. All medications used are standard of care",[9],null,{"type":19,"name":25,"description":21,"armGroupLabels":26,"otherNames":23},"Dexmedetomidine",[9],{"type":19,"name":28,"description":29,"armGroupLabels":30,"otherNames":23},"Iohexol","The block solution will consist of 1% ropivacaine 3 mg\u002FKg ideal body weight (IBW) mixed with dexmedetomidine 0.5 mcg\u002FKg IBW and diluted with 10 mL iohexol 300 mg\u002FmL and normal saline for a total volume of 40 mL. All medications used are standard of care except for iohexol which is used for study purposes.",[9],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":23},"PROCEDURE","QST Procedure","The QST procedure (test of buzzing sensation and temperature sensation through pads applied to your skin) to assess the numb areas.",[9],[37],{"name":38,"affiliation":5,"role":39},"Salim Hayek, MD","PRINCIPAL_INVESTIGATOR",[41],{"name":42,"role":43,"phone":44,"phoneExt":23,"email":45},"Sena Ulucay, MD","CONTACT","216-84-3771","Ayse.Ulucay@UHhospitals.org",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","Cleveland","Ohio","44106","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-81.69541,41.4995,{"lat":58,"lon":57},[61],{"name":62,"role":43,"phone":63,"phoneExt":23,"email":45},"Ayse Ulucay, MD","216-844-3771",{"type":39,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Salim M Hayek","Professor and Vice Chair for Clinical Research, Department of Anesthesiology","100606352","contrast-and-anesthetic-level-with-lumbar-erector-spinae-plan-esp-block-100606352",false,"NCT07174440","Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block","Erector Spinae Plane Block in Patients Undergoing Lumbar Spine Fusion Surgery: Iohexol Spread, Extent of Block and Efficacy","Inclusion Criteria:\n\n* Age range: Adult patients 21-75 years of age\n* ASA status: I-III\n* Planned lumbar spine fusion involving no more than three levels\n* Ability to ambulate prior to surgery\n\nExclusion Criteria:\n\n* Previous lumbar spine surgery\n* Metastatic cancer with involvement of the lumbar spine\n* eGFR \\\u003C 60 mL\u002Fmin\u002F1.73m2\n* Active liver disease (hepatitis or cirrhosis)\n* Confirmed allergy to ropivacaine, dexmedetomidine or iohexol\n* Cognitive impairment resulting in inability to rate pain scores\n* Patients receiving 30 mg or more of morphine equivalent daily dosing preoperatively\n* Pregnancy","ALL","21 Years","75 Years",{"count":78,"type":79},32,"ESTIMATED","INTERVENTIONAL",[82],"NA","As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block. Through the needle, a small catheter will be placed in the participants back and the needle removed. Approximately one hour prior to the start of surgery, a numbing medication (ropivacaine, similar to Novocaine) in combination with dexmedetomidine (a pain medicine that is used in nerve block and that is not a narcotic) and contrast dye (iohexol) will be injected through the catheter. Participants will then go through the QST procedure (test of buzzing sensation and temperature sensation through pads applied to their skin) to assess the numb areas and then head to the operating room. In the operating room, the catheter will be removed after the surgeon obtains baseline CT scan images of the spine. Once surgery is completed, investigators will record pain scores over the next four days in the hospital and the amount of pain medication needed for controlling pain related to the surgery.",[85],"Pain",[87,88],"Spinal surgery","ESP block","2026-03-09",{"date":91,"type":92},"2026-03-11","ACTUAL",{"date":94,"type":92},"2025-09-15",{"date":96,"type":79},"2027-01-25",{"name":5,"class":6},1]