[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100636059":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":34,"responsibleParty":52,"collaborators":19,"id":55,"slug":56,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":19,"eligibilityCriteria":61,"healthyVolunteers":62,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":19,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":81,"whyStopped":19,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Valencia","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Combined Dental Bleaching","EXPERIMENTAL","Participants will undergo a combined dental bleaching treatment consisting of an in-office phase followed by an at-home phase using custom trays.",[13],"Procedure: Combined Dental Bleaching",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"PROCEDURE","The intervention consists of an in-office bleaching phase with two 20-minute applications of 40% hydrogen peroxide, followed by an at-home bleaching phase using 16% carbamide peroxide applied with custom trays for 90 minutes daily. Treatment will continue until color stabilization is achieved, defined as a change in WID of less than 2.6 units between two consecutive weekly measurements.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"José Amengual-Lorenzo","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"José Amengual-Lorenzo, PhD","CONTACT","+34616941167","jose.amengual@uv.es",{"name":31,"role":27,"phone":32,"phoneExt":19,"email":33},"Rubén Agustín Panadero, MSc; Phd","+34653098901","ruben.agustin@uv.es",[35],{"facility":5,"status":19,"city":36,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Valencia","46010","Spain","ES",{"type":41,"coordinates":42},"Point",[43,44],-0.37966,39.47391,{"lat":44,"lon":43},[47,49,51],{"name":48,"role":27,"phone":28,"phoneExt":19,"email":29},"José Amengual Lorenzo, Phd",{"name":50,"role":27,"phone":32,"phoneExt":19,"email":33},"Rubén Agustín-Panader, MsC; PhD",{"name":26,"role":23,"phone":19,"phoneExt":19,"email":19},{"type":23,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"José Amengual Lorenzo","Assistant Professor of Stomatology","100636059","contribution-of-a-to-dental-bleaching-after-combined-dental-bleaching-100636059",false,"NCT07560761","Contribution of a* to Dental Bleaching After Combined Dental Bleaching","Contribution of the a* Parameter to Dental Bleaching After Combined Bleaching: A Prospective Non-randomized Single-arm Interventional Clinical Study","Inclusion Criteria\n\n* Age 18 to 65 years\n* Good oral health\n* Presence of natural anterior teeth (incisors, canines, premolars)\n* Anterior teeth without restorations\n* Indication for tooth bleaching treatment\n* Ability to comply with study procedures and visits\n\nExclusion Criteria\n\n* Smoking\n* Previous tooth bleaching treatment\n* Pregnancy\n* Breastfeeding\n* Restorations in anterior teeth\n* Presence of diseases affecting tooth color\n* Conditions that may interfere with study outcomes",true,"ALL","18 Years","65 Years",{"count":67,"type":68},10,"ESTIMATED","INTERVENTIONAL",[71],"NA","A prospective, non-randomized, single-arm interventional clinical study with a before-after design will be conducted to assess changes in CIELab color parameters and the Whiteness Index for Dentistry (WID) following a standardized combined dental bleaching protocol. The study aims to evaluate the contribution of the a\\* parameter (green-red axis) to overall dental whiteness.",[74],"Healthy",[76,77,78,79,80],"Dental bleaching","Tooth color","CIELab","Whiteness Index","Spectrophotometry","NOT_YET_RECRUITING","2026-04-30",{"date":84,"type":85},"2026-05-06","ACTUAL",{"date":87,"type":68},"2026-10-01",{"date":89,"type":68},"2027-07",{"name":5,"class":6},1]