[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570181":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":25,"responsibleParty":35,"collaborators":25,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":25,"eligibilityCriteria":43,"healthyVolunteers":39,"sex":44,"minAge":45,"maxAge":46,"enrollmentInfo":47,"targetDuration":25,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":56,"overallStatus":61,"whyStopped":25,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":25},{"fullName":5,"class":6},"First Affiliated Hospital Xi'an Jiaotong University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PD group","ACTIVE_COMPARATOR","Traditional minimally invasive pancreaticoduodenectomy",[13],"Procedure: Pancreaticoduodenectomy",{"label":15,"type":16,"description":17,"interventionNames":18},"expanded PD group","EXPERIMENTAL","Traditional minimally invasive pancreaticoduodenectomy combined with the TRIANGLE procedure",[19],"Procedure: Expanded pancreaticoduodenectomy surgery",[21,26],{"type":22,"name":23,"description":17,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Expanded pancreaticoduodenectomy surgery",[15],null,{"type":22,"name":27,"description":11,"armGroupLabels":28,"otherNames":25},"Pancreaticoduodenectomy",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Zheng Wang, Doctor","CONTACT","86+15902993665","zheng.wang11@mail.xjtu.edu.cn",{"type":36,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100570181","conventional-partial-pancreatoduodenectomy-versus-an-extended-pancreatoduodenectomy-for-pancreatic-head-cancers-100570181",false,"NCT06703905","Conventional Partial Pancreatoduodenectomy Versus an Extended Pancreatoduodenectomy for Pancreatic Head Cancers","Short and Long-term Outcomes of Minimally Invasive Pancreatoduodenectomy Combined with Triangle Operation for Resectable Pancreatic Cancer: an International Multicenter Randomized Controlled Study","Inclusion Criteria:\n\n1. Preoperative: a. Patients with suspected or histologically verified resectable, borderline or locally advanced pancreatic cancer of the pancreatic head (i.e. pancreatic ductal adenocarcinoma, intraductal papillary mucinous neoplasm (IPMN)-carcinoma or periampullary cancer of the pancreatobiliary-type) ; b. Patients scheduled for elective partial pancreatoduodenectomy (irrespective of neoadjuvant therapy); c. Assumed resectability in accordance with the surgical protocol for experimental and control intervention as judged by the treating surgeon; d. Ability of the subject to understand character and individual consequences of the clinical trial;e.Written informed consent; f. Age ≥ 18 years;\n2. Intraoperative: a.No distant metastases; b.No paraaortic lymph node metastases; c.Intraoperative confirmation that the patient can be operated on according to both surgical methods.\n\nExclusion Criteria:\n\n1. Participation in another interventional trial with the interference of intervention and outcome of this trial;\n2. American Society of Anesthesiologists (ASA) grade \\>3;\n3. Distant metastatic disease .","ALL","18 Years","100 Years",{"count":48,"type":49},270,"ESTIMATED","INTERVENTIONAL",[52],"NA","The goal of this clinical trial is to learn if traditional pancreaticoduodenectomy (PD) combined with TRIANGLE (extended PD surgery) can increase disease-free survival (DFS) in patients with pancreatic head cancers compared to traditional minimally invasive PD. The main questions it aims to answer are:\n\n* Does extended PD surgery increase disease-free survival (DFS)?\n* Does extended PD surgery could improve postoperative and long-term quality of life for patients? Researchers will compare extended PD surgery to traditional PD surgery to see if extended PD surgery could extend the survival time of patients.\n\nParticipants will:\n\n* Accept traditional minimally invasive PD surgery or minimally invasive PD combined with TRIANGLE surgery.\n* Visit the clinic once every 3 months for checkups and tests.\n* Keep a diary of their symptoms.",[55],"Pancreatic Cancer Resectable",[57,58,59,60],"Pancreatic cancer","pancreaticoduodenectomy","Minimally invasive surgery","Heidelberg Triangle","NOT_YET_RECRUITING","2024-11-21",{"date":64,"type":65},"2024-11-25","ACTUAL",{"date":67,"type":49},"2024-12",{"date":69,"type":49},"2028-12",{"name":5,"class":6}]