[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572999":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":25,"responsibleParty":32,"collaborators":25,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":25,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":25,"enrollmentInfo":45,"targetDuration":25,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":54,"overallStatus":57,"whyStopped":25,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":25},{"fullName":5,"class":6},"Shanghai Zhongshan Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"c-TEVAR","ACTIVE_COMPARATOR","conventional thoracic endovascular aortic repair",[13],"Procedure: thoracic endovascular aortic repair",{"label":15,"type":16,"description":17,"interventionNames":18},"Fabulous","EXPERIMENTAL","proximal stent graft combined with distal bare stent",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","thoracic endovascular aortic repair","stent-graft implanted to seal the proximal entry tear of type B aortic dissection",[15,9],null,[27],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Yuanqing Kan, MD","CONTACT","0086-13585939248","echok624@gmail.com",{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Lixin Wang","Professor","100572999","conventional-tevar-versus-fabulous-rct-100572999",false,"NCT06740565","Conventional TEVAR Versus FABULOUS RCT","A Multicenter, Prospective, Randomized Control Study on the Optimal Intervention Approach for High-risk Type B Aortic Dissection","Inclusion Criteria:\n\n* Males aged 18 years or older, or non-pregnant females\n\n  * Diagnosed with high-risk Type B aortic dissection with a narrow true lumen (defined as the minimum true lumen diameter being less than 30% of the total vessel diameter) and\u002For poor radiographic or clinical visceral perfusion (including abnormal blood supply to the liver, kidneys, mesentery, or lower limb ischemia)\n  * Deemed suitable for endovascular treatment according to the investigator's judgment\n  * Able to understand the purpose of the trial, willing to participate voluntarily and sign the informed consent form, and committed to follow-up visits.\n\nExclusion Criteria:\n\n* • Subjects with hemodynamic instability or ruptured aortic dissection\n\n  * Subjects who, due to various anatomical factors, are unable to undergo TEVAR alone\n  * Subjects with connective tissue diseases, such as Marfan syndrome\n  * Subjects in poor general condition, unable to tolerate general anesthesia\n  * Subjects allergic to contrast agents, nitinol stent materials, or other stent components\n  * Subjects with a life expectancy of less than 12 months\n  * Subjects with a history of myocardial infarction or unstable angina within the past 3 months\n  * Subjects with a history of TIA or cerebral infarction within the past 3 months\n  * Subjects with creatinine levels exceeding 2.5 times the upper normal limit or those currently on dialysis\n  * Subjects with severe conditions such as liver failure","ALL","18 Years",{"count":46,"type":47},392,"ESTIMATED","INTERVENTIONAL",[50],"NA","For High-risk Type B aortic dissections, a multicenter, prospective, randomized controlled study is conducted to compare the clinical outcomes of conventional proximal endovascular repair (TEVAR) alone versus the Fabulous system which includes a proximal stent graft with a distal bare metal stent implanted. The study aims to determine the optimal intervention method for such population.",[53],"Type B Aortic Dissection",[55,56],"endovascular repair","distal bare stent","NOT_YET_RECRUITING","2024-12-15",{"date":60,"type":61},"2024-12-18","ACTUAL",{"date":63,"type":47},"2025-02-01",{"date":65,"type":47},"2029-02-01",{"name":5,"class":6}]