[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100609980":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":25,"responsibleParty":38,"collaborators":10,"id":41,"slug":42,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":10,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":10,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":64,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Akron Children's Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Conventional ultrafiltration Group",null,"Conventional ultrafiltration will only have excess effluent removed during cardiopulmonary bypass.",{"label":13,"type":10,"description":14,"interventionNames":10},"Dilutional ultrafiltration Group","Dilutional ultrafiltration will have continuous removal of effluent and replacement of this fluid with Plasmalyte.",[16],{"name":17,"affiliation":5,"role":18},"Lindsey N Stuhm, MSHS CCP","PRINCIPAL_INVESTIGATOR",[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Lindsey N Stuhm, Cardiovascular Perfusion","CONTACT","3305438536","lstuhm@akronchildrens.org",[26],{"facility":5,"status":10,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":10},"Akron","Ohio","44308","United States","US",{"type":33,"coordinates":34},"Point",[35,36],-81.51901,41.08144,{"lat":36,"lon":35},{"type":18,"investigatorFullName":39,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Lindsey Stuhm","Certified Clinical Perfusionist","100609980","conventional-ultrafiltration-versus-dilutional-ultrafiltration-in-pediatric-cpb-patients-100609980",false,"NCT07221630","Conventional Ultrafiltration Versus Dilutional Ultrafiltration in Pediatric CPB Patients","Effects of Conventional and Dilutional Ultrafiltration Techniques During Cardiopulmonary Bypass in Pediatric Cardiac Patients","Inclusion Criteria:\n\n* Males and females less than 5 years of age\n* Cardiac operations utilizing CPB\n* Cardiac reoperations utilizing CPB\n\nExclusion Criteria:\n\n* Patients greater than 5 years of age.\n* Any active SYSTEMIC noncardiac disease expected to raise patient baseline CRP levels to above normal levels (\\>1mg\u002FdL). Since CRP levels correlate with the severity of most skin disease, patients with active dermatitis issues on the day of surgery will be excluded from the study. Patients with autoimmune diseases including RA, SLE, IBD (Crohn's disease, ulcerative colitis), Kawasaki disease and patients experiencing active infections will be excluded from the study.\n* Any noncardiac disease not well controlled (ex. Asthma not properly controlled with medication, etc.)\n* Recent viral illness (ex. Positive COVID\u002Fflu test 30 days prior to surgery)\n* All patients receive solumedrol (10mg\u002Fkg dose) from anesthesia as part of the prebypass protocol. Any patient currently taking steroids will also be excluded from the study\n* Non-cardiopulmonary bypass cases (Off pump CoA, Vascular ring surgery, etc.)\n* ECMO patients\n* Emergent cases",true,"ALL","1 Day","5 Years",{"count":53,"type":54},100,"ESTIMATED","OBSERVATIONAL","The investigators will be comparing two different filtration methods on cardiopulmonary bypass for pediatric heart surgery patients. Three blood tests will be taken from the patient to compare which filtration method is better at decreasing post-cardiopulmonary bypass inflammation caused by the heart-lung machine.",[58],"Systemic Inflammatory Response Syndrome",[60,61,62,63],"Dilutional Ultrafiltration","Conventional Ultrafiltration","Cardiopulmonary Bypass","C-reactive protein","NOT_YET_RECRUITING","2025-10-27",{"date":67,"type":68},"2025-10-28","ACTUAL",{"date":70,"type":54},"2026-01-01",{"date":72,"type":54},"2027-01-02",{"name":5,"class":6},1]