[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639765":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":25,"responsibleParty":43,"collaborators":45,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":51,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":74,"whyStopped":18,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Tel-Aviv Sourasky Medical Center","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention","EXPERIMENTAL","The intervention will include 3 follow-up visits in the flare up clinic - the first visit (following randomization) will occur one month after hospital discharge (from ED or admission, baseline), the second at 3 months, and the third visit will be at 12 months from baseline. At 6 and 9 months after inclusion there will be an additional phone-call with structured interview similar to that of the control group. Visits include clinical evaluation, symptom assessment, spirometry, oscillometry, inhaler technique review, cardiovascular risk assessment, and treatment optimization according to GOLD recommendations.",[13],"Other: Follow-up in a flare-up clinic",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","The control group will undergo baseline and 12 months in-person assessments including all questionnaires and physiological tests but without any medical interventions. Structured telephone follow-up at 3, 6, and 9 months will be performed by research coordinators to assess for the study outcomes.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"OTHER","Follow-up in a flare-up clinic","Participants in the intervention arm will attend a specialized \"COPD flare-up clinic\" for structured follow-up after hospitalization or ED visit due to acute COPD exacerbation. The program includes three in-person clinic visits at 1, 4, and 10 months after the first visit, and two additional structured telephone follow-up at 10 and 18 months. To assess cardiovascular outcomes, a follow-up phone call will be conducted 24 months after Visit 1.",[9],[26],{"facility":27,"status":18,"city":28,"state":18,"zip":18,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Tel Aviv Sourasky Medical Center, Tel Aviv, 6423906","Tel Aviv","Israel","IL",{"type":32,"coordinates":33},"Point",[34,35],34.78057,32.08088,{"lat":35,"lon":34},[38],{"name":39,"role":40,"phone":41,"phoneExt":18,"email":42},"Ophir Freund, Medical Doctor (Pulmonologist)","CONTACT","+972545305648","ophir068@gmail.com",{"type":44,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR",[46],{"name":47,"class":48},"AstraZeneca","INDUSTRY","100639765","copd-flare-up-clinic-after-severe-exacerbations-100639765",false,"NCT07629869","COPD Flare-Up Clinic After Severe Exacerbations","The Role of COPD Flare-up Clinic Service After Severe Exacerbations to Reduce Recurrent Exacerbations","FLARE-COPD","Inclusion Criteria:\n\n* Prior COPD diagnosis based on clinical and spirometry accepted criteria.\n* Acute exacerbation of COPD as the main reason for ED arrival.\n* Ability to perform in-person and telephone follow-up.\n* Agree to participate, with a signed informed consent.\n\nExclusion Criteria:\n\n* Symptomatic heart failure as the main reason for emergency department visit in the last 6 months.\n* Uncontrolled comorbidity.\n* Vulnerable Populations: To ensure ethical compliance and participant safety, the study will exclude vulnerable populations. This includes pregnant women, and any person lacking the mental or legal capacity to provide independent informed consent.","ALL","40 Years","80 Years",{"count":61,"type":62},240,"ESTIMATED","INTERVENTIONAL",[65],"NA","This prospective randomized controlled trial evaluates whether a specialized \"COPD flare-up clinic service\" improves outcomes in patients following an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Patients presenting to the emergency department with AECOPD and discharged or hospitalized will be randomized 1:1 to either structured follow-up in a dedicated flare-up clinic or standard follow-up by scheduled telephone interviews.\n\nThe researches hypothesize that structured follow-up in a specialized clinic will reduce recurrent exacerbations, optimize long-term COPD management, and improve patients' quality of life compared to standard care.",[68,69],"COPD","COPD Exacerbation (AECOPD)",[71,72,73],"COPD management","COPD flare-up","COPD exacerbation","NOT_YET_RECRUITING","2026-06-18",{"date":77,"type":78},"2026-06-23","ACTUAL",{"date":80,"type":62},"2026-07-01",{"date":82,"type":62},"2028-12-31",{"name":5,"class":6},1]