[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560328":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":55,"collaborators":57,"id":61,"slug":62,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":65,"acronym":24,"eligibilityCriteria":66,"healthyVolunteers":63,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":24,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":24,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Duke University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Step Up","EXPERIMENTAL","Step Up participants will complete 7 sessions over 7-14 weeks (45 min\u002Fsession). Of the 7 sessions, participants will complete 3 in-person in the hospital\u002Foutpatient clinic (1 coping skills training for symptom management \\[45 min\\] and 2 activity coaching \\[45 min\\]) followed by 4 via videoconferencing (coping skills training for symptom management and activity coaching \\[45 min each\\]) once the patient has been discharged home from the outpatient clinic.",[13],"Behavioral: Step Up",{"label":15,"type":6,"description":16,"interventionNames":17},"Usual Care Plus (UC+)","Usual Care Plus (UC+) participants will complete all assessments at time intervals corresponding to Step Up, and otherwise continue to receive their usual medical care plus 7 videos delivering educational content (1 video\u002Fweek for 7 weeks; 5-10 minutes\u002Fvideo) via a study app (free download), but not the Step Up protocol.",[18],"Other: Usual Care Plus (UC+)",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","A hybrid in-person and mHealth (mobile health) coping skills training and activity coaching intervention.",[9],null,{"type":6,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Usual medical care plus videos delivering educational content via an app.",[15],[29,34],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Allison Diachina","CONTACT","919-416-3421","allison.diachina@duke.edu",{"name":35,"role":31,"phone":24,"phoneExt":24,"email":36},"Sarah Kelleher, PhD","sarah.kelleher@duke.edu",[38],{"facility":39,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Duke Cancer Institute","RECRUITING","Durham","North Carolina","27705","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-78.89862,35.99403,{"lat":50,"lon":49},[53],{"name":54,"role":31,"phone":24,"phoneExt":24,"email":24},"Sarah A Kelleher, PhD",{"type":56,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[58],{"name":59,"class":60},"National Institutes of Health (NIH)","NIH","100560328","coping-skills-training-for-symptom-management-and-daily-steps-step-up-100560328",false,"NCT06575712","Coping Skills Training for Symptom Management and Daily Steps (Step Up)","Inclusion Criteria:\n\n* receipt of an autologous (auto) HCT or CAR-T cell therapy due to a hematologic malignancy, such as a diagnosis of leukemia, lymphoma, multiple myeloma\n* age \\>18\n* self-reported fatigue, pain, and psychological distress (confirmed at recruitment) - minimum two of three symptoms reported at \\>3 on 0-10 scale\n* life expectancy \\> 12 months\n\nExclusion Criteria:\n\n* cognitive impairment (e.g., dementia) recorded in the chart or suspected by provider\n* metastases to the brain\n* presence of a severe psychiatric condition (e.g., psychotic disorder) that would contraindicate safe participation as indicated by the medical chart, treating oncologist, or interactions with the medical\u002Fstudy staff\n* inability to converse in English","ALL","18 Years","99 Years",{"count":71,"type":72},177,"ESTIMATED","INTERVENTIONAL",[75],"NA","The aim of this study is to test the efficacy of a hybrid in-person and mHealth coping skills training and activity coaching intervention (Step Up), to enable HCT patients to effectively cope with symptoms (pain, fatigue, and stress) to improve their ability to engage in physical activity that can improve physical disability.",[78,79],"Hematopoietic Stem Cell Transplant","CAR-T Cell Therapy","2026-06-24",{"date":82,"type":83},"2026-06-25","ACTUAL",{"date":85,"type":83},"2025-04-21",{"date":87,"type":72},"2029-07-15",{"name":5,"class":6},1]