[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100572304":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":54,"centralContacts":58,"locations":64,"responsibleParty":80,"collaborators":84,"id":87,"slug":88,"hasResults":89,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":95,"sex":96,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":10,"studyType":102,"phases":10,"briefSummary":103,"conditions":104,"keywords":108,"overallStatus":67,"whyStopped":10,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Aristotle University Of Thessaloniki","OTHER",[8,20],{"label":9,"type":10,"description":11,"interventionNames":12},"PEX group (patients WITH pseudoexfoliation syndrome)",null,"right or left eye of pseudophakic patients diagnosted with PEX syndrome pre-operatively (PEX positive, as recorded in the pre-operative medical file)",[13,14,15,16,17,18,19],"Device: Pentacam-AXL","Device: HD Analyzer","Device: Corvis ST","Device: OCT-A Angiovue","Device: IOLMaster V.5.4","Device: Topcon SP-1P","Other: BCVA (ETDRS), Slit lamp examination, Goldmann Applanation Tonometry, Fundus examination",{"label":21,"type":10,"description":22,"interventionNames":23},"Control group (patients WITHOUT pseudoexfoliation syndrome)","right or left eye of pseudophakic patients without a pre-operative diagnosis of pseudoexfoliation syndrome (PEX negative, as recorded in the pre-operative medical file)",[13,14,15,16,17,18,19],[25,30,34,38,42,46,50],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":10},"DEVICE","Pentacam-AXL","Pentacam-AXL (Oculus, Wetzlar, Germany)",[21,9],{"type":26,"name":31,"description":32,"armGroupLabels":33,"otherNames":10},"HD Analyzer","HD Analyzer (Visiometrics, Terassa, Spain, Keeler)",[21,9],{"type":26,"name":35,"description":36,"armGroupLabels":37,"otherNames":10},"Corvis ST","Corvis ST (Oculus, Germany)",[21,9],{"type":26,"name":39,"description":40,"armGroupLabels":41,"otherNames":10},"OCT-A Angiovue","OCT-A Angiovue (Optovue, Inc., Fremont, California, USA)",[21,9],{"type":26,"name":43,"description":44,"armGroupLabels":45,"otherNames":10},"IOLMaster V.5.4","IOLMaster V.5.4 (Carl Zeiss., Meditec)",[21,9],{"type":26,"name":47,"description":48,"armGroupLabels":49,"otherNames":10},"Topcon SP-1P","Topcon SP-1P (Topcon Medical Inc., Tokyo, Japan)",[21,9],{"type":6,"name":51,"description":52,"armGroupLabels":53,"otherNames":10},"BCVA (ETDRS), Slit lamp examination, Goldmann Applanation Tonometry, Fundus examination","BCVA (ETDRS), Slit lamp examination, Goldmann Applanation Tonometry, Fundus Examination",[21,9],[55],{"name":56,"affiliation":5,"role":57},"Nikolaos Ziakas, Professor","STUDY_CHAIR",[59],{"name":60,"role":61,"phone":62,"phoneExt":10,"email":63},"Paraskevi Petridou, MD, MSc","CONTACT","00306985565799","evina_petridou@hotmail.com",[65],{"facility":66,"status":67,"city":68,"state":10,"zip":69,"country":70,"countryCode":71,"cosmosGeoPoint":72,"geoPoint":77,"contacts":78},"2nd Department of Ophthalmology, Papageorgiou General Hospital","RECRUITING","Thessaloniki","56429","Greece","GR",{"type":73,"coordinates":74},"Point",[75,76],22.93493,40.64072,{"lat":76,"lon":75},[79],{"name":60,"role":61,"phone":62,"phoneExt":10,"email":63},{"type":81,"investigatorFullName":82,"investigatorTitle":83,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Nikolaos Ziakas","Professor of Ophthalmology",[85],{"name":86,"class":6},"Papageorgiou General Hospital","100572304","corneal-biomechanics-optical-properties-and-anterior-segment-structural-features-in-patients-with-pseudoexfoliation-100572304",false,"NCT06731530","Corneal Biomechanics, Optical Properties and Anterior Segment Structural Features in Patients With Pseudoexfoliation","A Comparative Study of Anterior Segment Structural Features, Biomechanical Behaviour and Optical Properties of the Cornea in Patients With and Without Pseudoexfoliation Syndrome.","CorPEX","Inclusion Criteria:\n\n* age 60-80 years.\n* unilateral or bilateral pseudophakia (cataract surgery undergone at Papageorgiou General Hospital, Thessaloniki, Greece).\n* open anterior chamber angle (grade \\> 2, van Herick method).\n\nExclusion Criteria:\n\n* History of intraocular surgery other than uncomplicated cataract surgery (phakoemulsification).\n* Cataract surgery within the last 3 months.\n* History of ocular trauma.\n* Use of contact lenses.\n* Corneal pathology.\n* Use of anti-VEGF medications.\n* History of uveitis or active uveitis.\n* Hypertension (IOP \\> 21 mmHg) or glaucoma.\n* Myopia or hyperopia greater than 3 diopters.\n* Astigmatism greater than 1.5 diopters.\n* Posterior capsular opacification grade 2, 3, or 4 based on the EPCO grading scale.\n* Tear break-up time \\\u003C10 sec",true,"ALL","60 Years","80 Years",{"count":100,"type":101},86,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to assess the effect of pseudoexfoliation syndrome on corneal biomechanics, optical clarity of the cornea, and anterior segment structural features.",[105,106,107],"Pseudoexfoliation Syndrome","Biomechanical Parameters","Corneal Densitometry",[109,110,111],"pseudoexfoliation syndrome","biomechanical parameters","corneal transparency","2024-12-24",{"date":114,"type":115},"2024-12-27","ACTUAL",{"date":117,"type":115},"2024-12-13",{"date":119,"type":101},"2025-05",{"name":5,"class":6},1]