[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100615236":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":11,"locations":11,"responsibleParty":20,"collaborators":11,"id":22,"slug":23,"hasResults":24,"nctId":25,"briefTitle":26,"officialTitle":26,"acronym":27,"eligibilityCriteria":28,"healthyVolunteers":24,"sex":29,"minAge":30,"maxAge":11,"enrollmentInfo":31,"targetDuration":11,"studyType":34,"phases":35,"briefSummary":37,"conditions":38,"keywords":11,"overallStatus":42,"whyStopped":11,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":11},{"fullName":5,"class":6},"Universitair Ziekenhuis Brussel","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Chronic musculoskeletal pain group","EXPERIMENTAL",null,[13],"Procedure: cryoablation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"PROCEDURE","cryoablation","Cryoneurolysis",[9],{"type":21,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100615236","correlation-between-diagnostic-nerve-block-response-and-cryoneurolysis-outcome-in-chronic-musculoskeletal-disorders-100615236",false,"NCT07289984","Correlation Between Diagnostic Nerve Block Response and Cryoneurolysis Outcome in Chronic Musculoskeletal Disorders","CRYONIC","Inclusion Criteria:\n\n* Be over 18 year old\n* Adults (\\> 18y) with either chronic musculoskeletal pain (\\> 3 months; average NRS \\> 5\u002F10) or painful\u002Ffunctionally limiting spasticity\n* Have a clinical stable condition, \\> 3months\n* Any medications must be maintained on a stable schedule- Able to understand study instructions and provide informed consent (ICF) in French or Dutch.Provide written informed consent\n\nExclusion Criteria:\n\n* Contraindication to cryoneurolysis such as a diagnosis of cryoglobulinemia, paroxysmal cold haemoglobinuria, cold urticaria, Raynaud's disease, any form of peripheral neuropathy, open and or infected wounds of the affected limb\n* Patient's refusal to give consent to the procedure or to use of their data for research purposes.\n* Ongoing local or systemic infection before the procedure.\n* Predominantly neuropathic pain of the upper extremity as assessed with the Pain Detect questionnaire","ALL","18 Years",{"count":32,"type":33},50,"ESTIMATED","INTERVENTIONAL",[36],"NA","The clinical study is titled the CRYONIC PROTOCOL, which stands for Cryotherapy for Neurolysis In Chronic Pain. It is structured as a prospective, multi-cohort observational study.\n\nPurpose of the Study:\n\nThe overarching purpose of the CRYONIC PROTOCOL study is to assess the Correlation Between Diagnostic Nerve Block Response and Cryoneurolysis Outcome in Chronic Musculoskeletal Disorders. The study focuses on evaluating the effectiveness of ultrasound-guided peripheral nerve cryoneurolysis, a minimally invasive technique that uses extreme cold to induce temporary nerve blocks, for patients with treatment-resistant chronic musculoskeletal pain.\n\nThe study also seeks to determine if cryoneurolysis itself leads to meaningful improvements in both pain intensity and functional ability in the included patient cohorts.",[39,40,41],"Chronic Musculoskeletal Pain","Cryo Analgesia","Cryoablation","NOT_YET_RECRUITING","2026-04-21",{"date":45,"type":46},"2026-04-27","ACTUAL",{"date":48,"type":33},"2026-07-01",{"date":50,"type":33},"2031-08-01",{"name":5,"class":6}]