[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100417461":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":24,"centralContacts":28,"locations":37,"responsibleParty":54,"collaborators":11,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":11,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":11,"enrollmentInfo":66,"targetDuration":11,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":39,"whyStopped":11,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Vanderbilt University Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Neural recordings and stimulation","EXPERIMENTAL",null,[13,14],"Other: Neurophysiology recordings","Other: Neural stimulation",[16,20],{"type":6,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"Neurophysiology recordings","Neurophysiology recordings will be performed during deep brain stimulation surgery and their relationship to performance on a gambling task evaluated",[9],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"Neural stimulation","Neural stimulation will be delivered during a gambling task and its impact on task performance quantified",[9],[25],{"name":26,"affiliation":5,"role":27},"Sarah Bick, MD","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":11,"email":33},"Lucas Chang, BA","CONTACT","615-421-3046","lucas.m.chang@vumc.org",{"name":26,"role":31,"phone":35,"phoneExt":11,"email":36},"615-343-9822","Sarah.Bick@vumc.org",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Nashville","Tennessee","37212","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-86.78444,36.16589,{"lat":49,"lon":48},[52,53],{"name":30,"role":31,"phone":32,"phoneExt":11,"email":33},{"name":26,"role":27,"phone":11,"phoneExt":11,"email":11},{"type":27,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Sarah Bick","Assistant Professor of Neurosurgery, Principal Investigator","100417461","corticostriatal-contributions-to-parkinsons-disease-cognitive-impairment-100417461",false,"NCT04715984","Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment","Corticostriatal Neurophysiology in Parkinson's Disease Cognitive Impairment","Inclusion criteria:\n\n* Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center\n* Planned clinical electrode trajectory that contacts caudate\n* Age greater than or equal to 40\n* Diagnosis of Parkinson's disease\n* Able to participate in intraoperative testing\n* English speaking\n\nExclusion criteria:\n\n* Age less than 40\n* Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)\n* Movement disorder other than Parkinson's disease","ALL","40 Years",{"count":67,"type":68},75,"ESTIMATED","INTERVENTIONAL",[71],"NA","The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.",[74],"Parkinson Disease",[76],"Deep Brain Stimulation","2026-06-10",{"date":79,"type":80},"2026-06-12","ACTUAL",{"date":82,"type":80},"2021-06-02",{"date":84,"type":68},"2029-08",{"name":5,"class":6},1]