[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598552":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":17,"centralContacts":29,"locations":35,"responsibleParty":52,"collaborators":17,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":17,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":77,"overallStatus":83,"whyStopped":17,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Centre Hospitalier Universitaire, Amiens","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"comparator","EXPERIMENTAL","On separate days, 50 patients with COPD completed four sets of 4-min at 85% of VO2peak intercept by 3-min of passive recovery in two randomized between-sets recovery conditions. Rating exertion perception, gaz exchanges, heart rate, sleep quality and nocturnal heart rate variability were assessed.",[13],"Other: Normobaric hypoxia",{"label":15,"type":16,"description":17,"interventionNames":18},"sham","SHAM_COMPARATOR",null,[19],"Other: normoxic condition",[21,25],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":17},"Normobaric hypoxia","Normobaric hypoxia (inspired oxygen fraction of 12.9%) applied between-sets recovery periods",[9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":17},"normoxic condition","Between-sets recovery periods under normoxic condition",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":17,"email":34},"Emeric Thiesset, MD","CONTACT","33+322088051","thiesset.emeric@chu-amiens.fr",[36],{"facility":37,"status":17,"city":38,"state":17,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"CHRU Amiens","Amiens","80480","France","FR",{"type":43,"coordinates":44},"Point",[45,46],2.3,49.9,{"lat":46,"lon":45},[49],{"name":31,"role":32,"phone":50,"phoneExt":17,"email":51},"33+3 22 08 80 51","Thiesset.emeric@chu-amiens.fr",{"type":53,"investigatorFullName":17,"investigatorTitle":17,"investigatorAffiliation":17,"oldNameTitle":17,"oldOrganization":17},"SPONSOR","100598552","cpod-patients-tolerance-of-intermittent-exercise-with-inter-exercise-recovery-under-normoxic-hypoxia-100598552",false,"NCT07072975","CPOD Patient's Tolerance of Intermittent Exercise With Inter-exercise Recovery Under Normoxic Hypoxia","HypoChronoPerf","Inclusion Criteria:\n\n* from 40 to 60 years\n* follow-up in the pneumology unit of CHU Amiens - Picardie\n* Chronic Obstructive Pulmonary Disease stade II\n* Body mass index from 20 to 30 kg.m-2\n* Tiffeneau index \\\u003C 70% of predicted value\n* FEV1 from 50 to 80% of predicted values\n* Smoking cessation since at least 1 week\n* Sedentary or physical active\n* Affiliate to social security\n* Written consent\n\nExclusion Criteria:\n\n\\-","ALL","40 Years","60 Years",{"count":65,"type":66},50,"ESTIMATED","INTERVENTIONAL",[69],"NA","Exercise retraining improves the prognosis and quality of life of patients with chronic lung or circulatory diseases. However, exercise intolerance may be caused by excessive ventilatory. Exposure to oxygen-replete air reduces this ventilatory overload, improves sleep and enhances responses to exercise. This study examine the impact of the acute manipulation of oxygen availability during inter-exercise recovery period of an intermittent cycling exercise on perceptual responses.\n\nthis randomized, controlled, study include adult patient with COPD. On separate days, 50 patients with COPD completed four sets of 4-min at 85% of VO2peak intercept by 3-min of passive recovery in two randomized between-sets recovery conditions. Rating exertion perception, gaz exchanges, heart rate, sleep quality and nocturnal heart rate variability were assessed.\n\nHypoxic exposure during inter-repetition recovery phases would reduce the ventilatory load during exercise. What's more, patients would not be forced to perform the sporting gesture in a restricted space or wearing a mask, limiting dyspnea and the perceived difficulty of the effort. Lastly, the induction of hypoxic stress during the re-training session helped to improve patients' sleep.",[72,73,74,75,76],"Intermittent Hypoxia","Exercise Recovery","Intermittent Exercise","Rating Exertion Perception","Sleep",[78,79,80,81,82],"intermittent hypoxia","exercise recovery","intermittent exercise","rating exertion perception","sleep","NOT_YET_RECRUITING","2025-09-30",{"date":86,"type":87},"2025-10-01","ACTUAL",{"date":89,"type":66},"2025-10",{"date":91,"type":66},"2027-08",{"name":5,"class":6},1]