[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100582922":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":22,"locations":10,"responsibleParty":28,"collaborators":10,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":36,"acronym":37,"eligibilityCriteria":38,"healthyVolunteers":39,"sex":40,"minAge":41,"maxAge":42,"enrollmentInfo":43,"targetDuration":10,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":50,"overallStatus":55,"whyStopped":10,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":10},{"fullName":5,"class":6},"IRCCS San Raffaele","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Schizophrenia Group",null,"We will enroll 50 patients selected according to the presence of Schizophrenia diagnosis (DSM V criteria), which will be tested for metaphor comprehension, as well as for the other variables included in the study, and the electrical brain activity will be registered through a 128 channel EEG.\n\nAmong these, a subgroup of 10 subjects will undergo a cognitive remediation training (Cognitive Remediation), already published and demonstrated to be feasible for patients with schizophrenia. Specifically, it consists of 15 sessions of 45 minutes each, including computerized domain-specific neurocognitive exercises aimed at training specific cognitive areas known to be impaired in schizophrenia.",[13],"Other: Cognitive Remediation",{"label":15,"type":10,"description":16,"interventionNames":10},"Healthy controls","50 healthy subjects, as control sample, that will be tested for metaphor comprehension, as well as for the other variables included in the study, and the electrical brain activity will be registered through a 128 channel EEG.",[18],{"type":6,"name":19,"description":20,"armGroupLabels":21,"otherNames":10},"Cognitive Remediation","10 patients will undergo a rehabilitative training (Cognitive Remediation), already published and demonstrated to be feasible for patients with schizophrenia. This program includes domain-specific neurocognitive exercises aimed at training specific cognitive areas known to be impaired in schizophrenia. The treatment plan includes 15 45-minutes sessions.",[9],[23],{"name":24,"role":25,"phone":26,"phoneExt":10,"email":27},"Giulia Agostoni, PsyD, PhD","CONTACT","00393938584311","agostoni.giulia@hsr.it",{"type":29,"investigatorFullName":30,"investigatorTitle":31,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Giulia Agostoni","PsyD, PhD","100582922","cracking-the-heterogeneity-of-social-outcome-through-neuropsychophysiological-profiles-100582922",false,"NCT06869616","CRacking the HEterogeneity of Social Outcome Through Neuropsychophysiological Profiles","CRHESO","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Diagnosis of Schizophrenia according to DSM V criteria\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Intellectual disability\n* Neurological disorder",true,"ALL","18 Years","65 Years",{"count":44,"type":45},100,"ESTIMATED","OBSERVATIONAL","CRHESO aims at overcoming the considerable burden of mental disorders, which affects both psychosocial well-being and societal welfare, through a multidisciplinary and integrated approach to explore and remediate dimensions affecting social outcome.",[49],"Schizophenia Disorder",[51,52,53,54],"electrophysiology","metaphor comprehension","language disorder","social functioning","NOT_YET_RECRUITING","2025-03-05",{"date":58,"type":59},"2025-03-11","ACTUAL",{"date":61,"type":45},"2025-05-01",{"date":63,"type":45},"2028-01-01",{"name":5,"class":6}]