[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100540572":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":15,"responsibleParty":35,"collaborators":7,"id":37,"slug":38,"hasResults":39,"nctId":40,"briefTitle":41,"officialTitle":42,"acronym":43,"eligibilityCriteria":44,"healthyVolunteers":39,"sex":45,"minAge":46,"maxAge":7,"enrollmentInfo":47,"targetDuration":7,"studyType":50,"phases":7,"briefSummary":51,"conditions":52,"keywords":7,"overallStatus":18,"whyStopped":7,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"Istituto Auxologico Italiano","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":13,"email":14},"Nicola Ticozzi, MD, PhD","CONTACT","+390261911","2937","n.ticozzi@auxologico.it",[16],{"facility":17,"status":18,"city":19,"state":20,"zip":21,"country":22,"countryCode":23,"cosmosGeoPoint":24,"geoPoint":29,"contacts":30},"Ospedale San Luca","RECRUITING","Milan","MI","20149","Italy","IT",{"type":25,"coordinates":26},"Point",[27,28],12.59836,42.78235,{"lat":28,"lon":27},[31],{"name":32,"role":11,"phone":33,"phoneExt":13,"email":34},"Alberto Doretti, MD","+0261911","a.doretti@auxologico.it",{"type":36,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100540572","creation-of-a-clinical-database-for-the-study-of-phenotypic-variability-in-motor-neuron-diseases-100540572",false,"NCT06318585","Creation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron Diseases","Creazione di un Database Clinico Per lo Studio Della variabilità Fenotipica Nella Malattia Del Motoneurone","ALS-PHENO","Inclusion Criteria:\n\n* diagnosis of ALS or other motor neuron disease\n\nExclusion Criteria:\n\n* refusal to participate to the study","ALL","18 Years",{"count":48,"type":49},200,"ESTIMATED","OBSERVATIONAL","Study Description: Characterization of Motor Neuron Disease Phenotypes\n\nThe goal of this observational study is to understand the clinical presentation of motor neuron disease (MND) in patients attending the Neurology Department of the Istituto Auxologico Italiano. The main questions it aims to answer are:\n\n* What are the specific clinical phenotypes associated with MND?\n* How can these phenotypes contribute to a better understanding of the disease's underlying mechanisms and improve prognostic accuracy?\n\nParticipants will undergo:\n\n* Clinical evaluation using validated scales\n* Neurophysiological and neuroradiological instrumental assessment\n* Neuropsychological evaluation\n* Collection of biological materials for genetic screening and biomarker assessment, if necessary.",[53,54],"Amyotrophic Lateral Sclerosis","Motor Neuron Disease","2025-05-05",{"date":57,"type":58},"2025-05-07","ACTUAL",{"date":60,"type":58},"2023-04-03",{"date":62,"type":49},"2026-12-31",{"name":5,"class":6},1]