[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608028":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":25,"responsibleParty":36,"collaborators":40,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":25,"eligibilityCriteria":49,"healthyVolunteers":50,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":25,"studyType":57,"phases":58,"briefSummary":60,"conditions":61,"keywords":25,"overallStatus":63,"whyStopped":25,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":25},{"fullName":5,"class":6},"Menoufia University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Narrow tie-base abutment","EXPERIMENTAL","Patients received subcrestal bone-level implants restored with narrow tie-base abutments.",[13],"Device: Intervention Name (Arm 1): Narrow tie-base abutment Intervention Name (Arm 2): Regular tie-base abutment",{"label":15,"type":16,"description":17,"interventionNames":18},"Regular tie-base abutment","PLACEBO_COMPARATOR","Patients received subcrestal bone-level implants restored with regular tie-base abutments.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Intervention Name (Arm 1): Narrow tie-base abutment Intervention Name (Arm 2): Regular tie-base abutment","Arm 1 - Narrow tie-base abutment\n\nIntervention Name: Narrow tie-base abutment\n\nIntervention Type: Device\n\nIntervention Description: Participants received a subcrestal bone-level dental implant restored with a narrow-diameter tie-base abutment.\n\nArm 2 - Regular tie-base abutment\n\nIntervention Name: Regular tie-base abutment\n\nIntervention Type: Device\n\nIntervention Description: Participants received a subcrestal bone-level dental implant restored with a regular-diameter tie-base abutment.",[9,15],null,[27,32],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Mohammed El-Sawy, PhD","CONTACT","00201061314522","Dr_sawy@windowslive.com",{"name":33,"role":29,"phone":34,"phoneExt":25,"email":35},"Mohammed T. Khater, PhD","00201003854552","MohamedKhaterdentalsmile1234@gmail.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Mohammed El-Sawy","Dr",[41],{"name":42,"class":6},"Mansoura University","100608028","crestal-bone-response-to-narrow-vs-regular-tie-base-in-subcrestal-implants-100608028",false,"NCT07196228","Crestal Bone Response to Narrow vs. Regular Tie-Base in Subcrestal Implants","Evaluation of Crestal Bone Changes at Subcrestal Bone-level Implants With Narrow or Regular Tie-base: A Randomized Controlled Trial","\\*\\*Inclusion Criteria\n\nAdults ≥18 years old.\n\nSingle missing tooth in a posterior quadrant, bordered by adjacent natural teeth.\n\nAdequate bone volume to place implants 8.5-10 mm in length and 4 mm in diameter without the need for bone or soft tissue grafting.\n\nPresence of a natural tooth or an implant-supported fixed restoration as an antagonist.\n\nGood oral hygiene with a plaque index \\\u003C25%.\n\nWilling and able to comply with study procedures and follow-up schedule.\n\nProvided written informed consent.\n\n\\*\\*Exclusion Criteria\n\nSystemic conditions or medications affecting bone metabolism (e.g., bisphosphonates, corticosteroids).\n\nUntreated periodontitis, persistent oral infections, or poor oral hygiene.\n\nMetabolic bone diseases (e.g., osteoporosis, renal insufficiency, immunodeficiency, leukocyte dysfunction).\n\nHistory of head and neck radiotherapy.\n\nPhysical or mental disability preventing adequate oral hygiene or compliance.\n\nHeavy smoking (\\>10 cigarettes\u002Fday).\n\nAlcoholism or drug abuse.\n\nPregnancy or breastfeeding.\n\nBruxism or oral mucosal diseases.\n\nNeed for bone regeneration procedures before implant placement.\n\nInability or unwillingness to attend follow-up visits.",true,"ALL","20 Years","70 Years",{"count":55,"type":56},40,"ESTIMATED","INTERVENTIONAL",[59],"NA","This 24-month randomized clinical trial evaluates peri-implant marginal bone changes at subcrestal implants restored with narrow versus regular tie-base abutments.\n\nThe study investigates whether narrow or regular tie-base abutments influence peri-implant crestal bone remodeling over 24 months.\n\nThis trial assesses the effect of abutment diameter (narrow vs. regular tie-base) on marginal bone stability at subcrestal implants after 24 months.\n\nWe aimed to determine if abutment diameter impacts peri-implant marginal bone levels by comparing narrow and regular tie-base abutments in a 24-month RCT.",[62],"Bone Loss","NOT_YET_RECRUITING","2025-09-19",{"date":66,"type":67},"2025-09-29","ACTUAL",{"date":69,"type":56},"2025-09-30",{"date":71,"type":56},"2028-12-01",{"name":5,"class":6}]