[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553248":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":46,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":10,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":76},{"fullName":5,"class":6},"Cairo University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Diabetic Neuropathy group",null,"The study design was a cross-cultural validation of Neuro Qol the Arabic version, for patients with DFUs. Three expert panels were involved in this study to test the face and content validity of the NeuroQol Arabic version. All experts had experience of not less than 10 years or at least a master's degree in physical therapy; a major part of their work is with the Arabic population; and they were also fluent in Arabic and English.\n\nTen patients per item were chosen to estimate the sample size for testing the psychometric properties of the Neuro Qol Arabic version. So 290 patients (145 male patients and 145 female patients), were chosen according to specific eligibility criteria.",[13],"Diagnostic Test: Neuropathy - and Foot Ulcer - Specific Quality of Life instrument (Neuro Qol)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Neuropathy - and Foot Ulcer - Specific Quality of Life instrument (Neuro Qol)","The NeuroQoL questionnaire is a valid, reliable, and self-reported questionnaire. It has 35-items with six domains namely, painful symptoms and paresthesia (items 1-7), reduction or loss of ability to feel (items 8-10), unsteadiness while walking\u002Fstanding\u002Fdiffuse sensory-motor symptoms (items 11-13), limitation in daily living (items 14 - 16), interpersonal problems (items 17-20), emotional distress (items 21- 27) and end with an overall assessment of quality of life or satisfaction with experiences in the above six domains \\[1 item in each domains, i.e. additional 6 items (items 28-33)\\]. The two final items (items 34-35) assess overall impact of neuropathy on QoL \\[5\\]. The scoring of the questionnaire is according to a five-point Likert scale, all the time, most of the time, some of the time, occasionally, never. Each domain has a maximum score 5 and minimum 1, where 5 means that the QoL is affected all the time because of the foot problem while 1 means never it affects their QoL",[9],[21],{"name":22,"affiliation":23,"role":24},"Engy BadrEldin S Moustafa, PhD","Faculty of Physical Therapy, Cairo University, Egypt","PRINCIPAL_INVESTIGATOR",[26,30],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","00201099445112","engybm.saleh@cu.edu.eg",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Shimaa T. AbulKasem, PhD","00201229823327","dr.shymaelshazly@yahoo.com",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":10,"geoPoint":10,"contacts":43},"Faculty of Physical Therapy, Cairo University","RECRUITING","Cairo","Giza Governorate","11432","Egypt","EG",[44,45],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},{"type":24,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Engy Badreldin Saleh Moustafa, PhD","Principal Investigator","100553248","cross-cultural-adaptation-and-validity-of-the-arabic-translated-neuropathy-specific-quality-of-life-questionnaire-100553248",false,"NCT06483620","Cross-cultural Adaptation and Validity of the Arabic-translated NEUROPATHY-SPECIFIC QUALITY OF LIFE Questionnaire","Neuropathy and Foot Ulcer_ Specific Quality of Life Instrument (Neuro QOL) Arabic Version: Cross-cultural Adaptation, Validity, and Reliability for Patients With Type 2 Diabetes","Inclusion Criteria:\n\n* Arabic is their first language The absence of any other neurological diagnosis affecting the sensory and motor system, such as stroke or multiple sclerosis\n* Age ranges between 18 and 70 years,\n* History of DM diagnosed by a physician and confirmed by either hemoglobin A1c ≥6.5% or the use of hypoglycemic agents.\n\nExclusion Criteria:\n\n* A hospital inpatient\n* Had pre-existing comorbidities such as cancer, shingles or other neuropathic pain entity that predated diabetes or can mimic or cause a neuropathic pain that is not arising as a result of diabetes.\n* Pregnant patients as diabetes may be of gestational type\n* Had recently experienced physical trauma that may have contributed to neuropathic pain had trauma or dermatological diseases of the skin as this could affect skin sensitivity (e.g. wounds, psoriasis and eczema).","ALL","18 Years","70 Years",{"count":60,"type":61},290,"ESTIMATED","OBSERVATIONAL","PURPOSE: This study will translate, culturally adapt, validate, and test the reliability of the Neuro Qol Arabic version to be used with diabetic patients in Arabic countries.\n\nBackground: The Neuropathy- and Foot Ulcer-Specific Quality of Life instrument is a multidimensional scale was developed to assess the QoL of diabetic patients with peripheral neuropathy. Producing Arabic versions of the Translating Scale can help researchers investigate offloading treatment among the Arabic population with DFUs.\n\nHypotheses: The study design was a cross-cultural validation of NeuroQol, the Arabic version, for patients with DFUs.\n\nResearch Question: Will there be cultural adaptation, validation, and reliability between the (Neuro Qol) Arabic version and the original language?",[65,66],"Diabetic Neuropathies","Diabetic Peripheral Neuropathy","2025-10-02",{"date":69,"type":70},"2025-10-03","ACTUAL",{"date":72,"type":70},"2025-02-13",{"date":74,"type":61},"2026-01-25",{"name":5,"class":6},1]