[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100543295":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":27,"centralContacts":32,"locations":38,"responsibleParty":70,"collaborators":10,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":10,"studyType":85,"phases":10,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":41,"whyStopped":10,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"Sensorion","INDUSTRY",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Patients with adulthood-onset bilateral sensorineural hearing loss (SNHL)",null,[12],"Genetic: Genotyping",{"label":14,"type":10,"description":10,"interventionNames":15},"Patients that carry mutations in the gene GJB2 from patients with adulthood-onset bilateral SNHL",[16],"Other: Audiological assessments",[18,23],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"GENETIC","Genotyping","Genotyping to determine if patients present mutations to the gene GJB2.",[9],{"type":24,"name":25,"description":25,"armGroupLabels":26,"otherNames":10},"OTHER","Audiological assessments",[14],[28],{"name":29,"affiliation":30,"role":31},"Maya ELZIERE, MD","Hôpital Eureopéen Marseille","PRINCIPAL_INVESTIGATOR",[33],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Lionel HOVSEPIAN, MD","CONTACT","+33786311376","lionel.hovsepian@sensorion-pharma.com",[39,56],{"facility":40,"status":41,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"The University of South Florida Board of Trustees","RECRUITING","Tampa","Florida","33620","United States","US",{"type":48,"coordinates":49},"Point",[50,51],-82.45843,27.94752,{"lat":51,"lon":50},[54],{"name":55,"role":35,"phone":10,"phoneExt":10,"email":10},"Victoria Sanchez, MD",{"facility":57,"status":41,"city":58,"state":10,"zip":59,"country":60,"countryCode":61,"cosmosGeoPoint":62,"geoPoint":66,"contacts":67},"CHU Gui de Chauliac","Montpellier","34295","France","FR",{"type":48,"coordinates":63},[64,65],3.87635,43.61093,{"lat":65,"lon":64},[68],{"name":69,"role":35,"phone":10,"phoneExt":10,"email":10},"Frederic Venail, Pr",{"type":71,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100543295","cross-sectional-and-prospective-study-to-characterize-early-onset-presbycusis-100543295",false,"NCT06354010","Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis","SONG","Inclusion Criteria:\n\n1. Female or Male patients ≥30 and ≤55 years old\n2. Bilateral hearing loss first noticed after the age of 16 years old\n3. Documented genotyping results showing mutations in GJB2 gene.\n\nExclusion Criteria:\n\n1. Deafness with a known, non-genetic cause\n2. To the opinion of the investigator, unable and\u002For unwilling to comply with all the protocol requirements and\u002For study procedures","ALL","30 Years","55 Years",{"count":83,"type":84},100,"ESTIMATED","OBSERVATIONAL","The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing loss carrying mutations on GJB2 gene.",[88],"Sensorineural Hearing Loss, Bilateral",[90,91,92,93,94,95,77,96,97],"Adulthood-onset bilateral sensorineural hearing loss","GJB2","Presbycusis","hearing impairement","Deafness","Connexin 26","Genetic deafness","Adult deafness","2026-05-04",{"date":100,"type":101},"2026-05-08","ACTUAL",{"date":103,"type":101},"2024-06-14",{"date":105,"type":84},"2027-07",{"name":5,"class":6},2]