[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100599502":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":19,"locations":24,"responsibleParty":41,"collaborators":10,"id":43,"slug":44,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":47,"acronym":10,"eligibilityCriteria":48,"healthyVolunteers":45,"sex":49,"minAge":10,"maxAge":10,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":57,"overallStatus":26,"whyStopped":10,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":68},{"fullName":5,"class":6},"St. Jude Children's Research Hospital","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"CSIMEMPHIS-only Group",null,"Participants meeting the CSIMEMPHIS eligibility criteria.",{"label":13,"type":10,"description":14,"interventionNames":10},"BRAINatomy2 Group","In addition to meeting the eligibility criteria for CSIMEMPHIS, the Brainatomy2 cohort participants must be able to tolerate non-sedated MRI and must not have a history of clinically significant PFS.",[16],{"name":17,"affiliation":5,"role":18},"Thomas E Merchant, DO, PhD","PRINCIPAL_INVESTIGATOR",[20],{"name":17,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","888-226-4343","referralinfo@stjude.org",[25],{"facility":5,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"RECRUITING","Memphis","Tennessee","38105","United States","US",{"type":33,"coordinates":34},"Point",[35,36],-90.04898,35.14953,{"lat":36,"lon":35},[39],{"name":40,"role":21,"phone":22,"phoneExt":10,"email":23},"Thomas E. Merchant, DO, PhD",{"type":42,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100599502","csimemphis-long-term-follow-up-of-medulloblastoma-survivors-that-received-craniospinal-irradiation-100599502",false,"NCT07085325","CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal Irradiation","Inclusion Criteria:\n\n* Diagnosis of any subtype of medulloblastoma between the ages of 3 to 22 years or between the ages of 22 to 44 years with the sonic hedgehog (SHH) subtype of medulloblastoma\n* Radiotherapy on or according to the SJMB12 protocol\n* 5 or more years since the initiation of radiation therapy and who did not have evidence of disease progression\n* Provision of informed consent by participant\u002Fguardian or legal representative; Assent by minor participant\n* Participants may choose to complete all or a subset of the proposed assessments; refusal to participate in some aspects of the study will not preclude participant inclusion\n* Participants must also complete enrollment on SJLIFE\n\nExclusion Criteria:\n\n* Participants or their legal guardian\u002Frepresentative are unwilling or unable to provide written informed consent.\n* Participants who had relapsed or refractory disease during or following completion of treatment for medulloblastoma","ALL",{"count":51,"type":52},184,"ESTIMATED","OBSERVATIONAL","The study is being done to learn more about the long-term health and well-being of participants treated for medulloblastoma. The study is to decide which evaluations focusing on therapy-related lasting effects (or toxicities) should be considered.\n\nMedulloblastoma outcomes have improved with contemporary therapies including modern neurosurgical techniques and risk-adapted radiotherapy and chemotherapy regimens. However, survivors remain at risk for long-term health problems such as neurocognitive deficits, hearing loss, impaired cardiorespiratory fitness and physical performance, cardiac and neuroendocrine dysfunction, musculoskeletal conditions, and infertility.",[56],"Medulloblastoma",[56,58],"Survivor","2026-04-21",{"date":61,"type":62},"2026-04-24","ACTUAL",{"date":64,"type":62},"2026-04-20",{"date":66,"type":52},"2031-10",{"name":5,"class":6},1]