[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621504":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":31,"locations":36,"responsibleParty":47,"collaborators":25,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":25,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":25,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":71,"overallStatus":76,"whyStopped":25,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Hanoi Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Connective Tissue Graft (CTG)","ACTIVE_COMPARATOR","Peri-implant soft tissue augmentation using autogenous connective tissue graft.",[13],"Procedure: Connective Tissue Graft",{"label":15,"type":16,"description":17,"interventionNames":18},"Collagen Matrix","EXPERIMENTAL","Peri-implant soft tissue augmentation using a collagen matrix.",[19],"Device: Collagen Matrix",[21,26],{"type":22,"name":15,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","A porcine-derived collagen matrix is used for peri-implant soft tissue augmentation at the time of implant surgery, serving as a substitute for autogenous connective tissue grafting.",[15],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":25},"PROCEDURE","Connective Tissue Graft","An autogenous connective tissue graft harvested from the patient is used for peri-implant soft tissue augmentation at the time of implant surgery.",[9],[32],{"name":33,"role":34,"phone":25,"phoneExt":25,"email":35},"Phu Manh Nguyen, DDS, MSc","CONTACT","manhphu@hmu.edu.vn",[37],{"facility":5,"status":25,"city":38,"state":25,"zip":25,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":25},"Hanoi","Vietnam","VN",{"type":42,"coordinates":43},"Point",[44,45],105.84117,21.0245,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","DUC NGUYEN MINH","DDS","100621504","ctg-versus-collagen-matrix-for-peri-implant-soft-tissue-augmentation-100621504",false,"NCT07371481","CTG Versus Collagen Matrix for Peri-Implant Soft Tissue Augmentation","Results of Soft Tissue Grafting Around Implant in the Mandible Molar Area","Inclusion Criteria:\n\nAdults aged 18 to 65 years.\n\nPatients requiring dental implant treatment in the mandibular molar region.\n\nPresence of insufficient peri-implant soft tissue thickness (\\\u003C 2 mm).\n\nAdequate general health to undergo minor oral surgery.\n\nAbility and willingness to provide written informed consent and comply with study procedures.\n\nExclusion Criteria:\n\nSystemic conditions or medications that may impair wound healing.\n\nHeavy smoking (more than 10 cigarettes per day).\n\nHistory of allergy or hypersensitivity to collagen-based materials.\n\nPrevious graft failure or complications at the intended implant site.\n\nLoss of three or more adjacent teeth in the study area (excluding third molars).","ALL","18 Years","65 Years",{"count":62,"type":63},46,"ESTIMATED","INTERVENTIONAL",[66],"NA","This randomized controlled trial compares two techniques for peri-implant soft tissue augmentation in the mandibular molar region: an autogenous connective tissue graft (CTG) and a collagen matrix. Adult patients requiring implant treatment with insufficient peri-implant soft tissue thickness will be randomly assigned to receive either CTG or a collagen matrix at the time of implant surgery.\n\nThe study aims to evaluate and compare changes in peri-implant soft tissue thickness, width of keratinized tissue, and soft tissue contour over a 9-month follow-up period, as well as the occurrence of postoperative complications. The results of this study will help determine whether a collagen matrix can provide clinical outcomes comparable to those of connective tissue grafting for peri-implant soft tissue augmentation.",[69,70],"Peri-implant Soft Tissue Deficiency","Insufficient Peri-implant Keratinized Tissue",[72,73,74,75],"Peri-implant soft tissue augmentation","Connective tissue graft","Collagen matrix","Dental implant","NOT_YET_RECRUITING","2026-01-27",{"date":79,"type":80},"2026-01-29","ACTUAL",{"date":82,"type":63},"2026-02",{"date":84,"type":63},"2028-12",{"name":5,"class":6},1]