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antero-posterior renal pelvic diameter (APRPD) in both positions.\n\nDiuretic renography to measure the cortical transit time",[13,14],"Device: ultrasonography","Device: diuretic renography",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"DEVICE","ultrasonography","bilateral ultrasonography to measure the antero-posterior renal pelvic diameter (APRPD) in both positions.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"diuretic renography","diuretic renography to measure the cortical transit time.",[9],[27],{"name":28,"affiliation":29,"role":30},"Luke Harper, MD","University Hospital, Bordeaux","PRINCIPAL_INVESTIGATOR",[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Lucie Auzanneau","CONTACT","0262359949","+262","lucie.auzanneau@chu-reunion.fr",{"name":39,"role":34,"phone":21,"phoneExt":21,"email":40},"Valérie 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Réunion","Saint-Denis","97400",{"type":50,"coordinates":103},[104,105],2.35387,48.93564,{"lat":105,"lon":104},[108,109],{"name":33,"role":34,"phone":21,"phoneExt":36,"email":37},{"name":110,"role":30,"phone":21,"phoneExt":21,"email":21},"Frédérique SAUVAT, MD, PhD",{"type":112,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR","100271373","ctt-on-renogram-as-an-early-marker-of-significant-obstruction-in-uretero-pelvic-junction-syndrome-100271373",false,"NCT02812212","CTT on Renogram as an Early Marker of Significant Obstruction in Uretero-pelvic Junction Syndrome","Cortical Transit Time on Diuretic Renogram as an Early Marker of Significant Obstruction in Antenatally Detected Uretero-pelvic Junction Syndrome","JUMP","Inclusion Criteria:\n\nInfants:\n\n* Aged of 4 to 8 weeks of life\n* Presenting an ureteropelvic junction obstruction (UPJO) detected before birth by ultrasound\n* Presenting an UPJO, defined by an Antero-Posterior Renal Pelvic Diameter greater or equal to 15 mm, confirmed by ultrasound post-natally between the 1st and 15th day of life\n* Presenting a unilateral UPJO\n* whose legal representatives have provided a signed free and informed written consent for their infant's participation\n* whose at least one of his legal representative is affiliated to national social security\n\nExclusion Criteria:\n\nInfants presenting:\n\n* A bilateral UPJO\n* An ureteral dilatation\n* An associated contralateral uropathy\n* A solitary kidney\n* A renal insufficiency\n* Severe associated disabilities ( ie polymalformation syndromes)\n* A concomitant participation in another trial\n* A contraindication to furosemide (acute renal insufficiency, hepatic encephalopathy, hypovolemia or dehydration, severe hypokalemia, severe hyponatremia)\n* A contraindication to the radionuclide marker (hypersensitivity to the active substance or to excipients)","ALL","4 Weeks","8 Weeks",{"count":125,"type":126},75,"ESTIMATED","INTERVENTIONAL",[129],"NA","Cortical transit time on diuretic renogram as an early marker of significant obstruction in antenatally detected uretero-pelvic junction syndrome",[132],"Ureteropelvic Junction Obstruction",[134,135],"ureteropelvic junction obstruction","cortical transit time","2022-09-27",{"date":138,"type":139},"2022-09-29","ACTUAL",{"date":141,"type":139},"2017-11-28",{"date":143,"type":126},"2027-04",{"name":5,"class":6},5]