[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100331231":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":33,"locations":42,"responsibleParty":66,"collaborators":10,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":74,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":10,"enrollmentInfo":79,"targetDuration":10,"studyType":82,"phases":10,"briefSummary":83,"conditions":84,"keywords":97,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Red group",null,"Those participants who had established diagnosis of one or more neurological and\u002For psychiatric conditions\n\nBaseline: The participants' medical history, signs, symptoms and diagnoses of neurological and\u002For psychiatric disorders would be recorded. Neuro-QoL questionnaire plus an additional subset of questions based on their clinical diagnosis should be done.",[13],"Behavioral: Neuro-QoL questionnaire",{"label":15,"type":10,"description":16,"interventionNames":17},"Yellow group","Those participants who are high-risk to develop one or more neurological and\u002For psychiatric conditions, for example:\n\n1. family history (first degree relative) one or more neurological and\u002For psychiatric conditions;\n2. examination, imaging or laboratory findings consistent with pre-symptomatic stages of one or more neurological and\u002For psychiatric disorders.\n\nBaseline: The participants' medical history, signs, symptoms and diagnoses of neurological and\u002For psychiatric disorders would be recorded. Neuro-QoL questionnaire should be done.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Green group","Those participants who are not meeting criteria for Red or Yellow groups, but interested in longitudinal research on maintenance and\u002For improvement of their brain health.\n\nBaseline: The participants' medical history would be recorded and Neuro-QoL questionnaire should be done.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"BEHAVIORAL","Neuro-QoL questionnaire","Follow-up over time will continue (either in-person or over the phone) using the same questionnaires (depending on which group they are belongs to) at approximately 6-month intervals. During each follow-up, participants will be screened for any new signs, symptoms and diagnoses of neurological and\u002For psychiatric disorders, in order to correlate these outcomes with risk factors captured using the procedures described above.",[19,9,15],[29],{"name":30,"affiliation":31,"role":32},"Thomas Wai Hong LEUNG, FRCP","Division of Neurology, The Chinese University of Hong Kong","PRINCIPAL_INVESTIGATOR",[34,38],{"name":30,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","852-35053593","drtleung@cuhk.edu.hk",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Tiffany Chung, M.Phil","852-35053856","tiffanyc@cuhk.edu.hk",[43,59],{"facility":5,"status":44,"city":45,"state":10,"zip":10,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Hong Kong","HK",{"type":48,"coordinates":49},"Point",[50,51],114.17469,22.27832,{"lat":51,"lon":50},[54,55],{"name":30,"role":35,"phone":36,"phoneExt":10,"email":37},{"name":56,"role":35,"phone":57,"phoneExt":10,"email":58},"Anki MIU, MSc","852-28902002","ankimiu@cuhk.edu.hk",{"facility":60,"status":44,"city":45,"state":10,"zip":10,"country":45,"countryCode":46,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"The Chinese University of Hong Kong",{"type":48,"coordinates":62},[50,51],{"lat":51,"lon":50},[65],{"name":30,"role":35,"phone":36,"phoneExt":10,"email":37},{"type":32,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Leung Wai Hong Thomas","Professor","100331231","cuhk-brain-health-longitudinal-study-100331231",false,"NCT03592563","CUHK Brain Health Longitudinal Study","BHS","Inclusion Criteria:\n\n1. Adult ≥ 18 years of age\n2. Fulfilling criteria for membership in one of these three groups:\n\n   * Red group: established diagnosis of one or more neurological and\u002For psychiatric conditions\n   * Yellow group: high-risk to develop one or more neurological and\u002For psychiatric conditions\n\n     1. family history (first degree relative) one or more neurological and\u002For psychiatric conditions\n     2. examination, imaging or laboratory findings consistent with pre-symptomatic stages of one or more neurological and\u002For psychiatric disorders\n   * Green group: not meeting criteria for Red or Yellow groups, but interested in longitudinal research on maintenance and\u002For improvement of brain health\n3. Subject provides informed consent by signing and dating the written informed consent form\n4. Subject is willing to answer health questionnaires and be followed longitudinally\n\nExclusion Criteria:\n\n* None",true,"ALL","18 Years",{"count":80,"type":81},5000,"ESTIMATED","OBSERVATIONAL","The goal of this study is to develop a large longitudinal cohort of individuals diagnosed with or at high risk for brain diseases (both neurological and psychiatric in nature), in order to identify risk factors that contribute to neurological and psychiatric diseases over time. The investigators seek to capture relevant information from medical records, electronically administered questionnaires and follow up phone-based interviews. The investigators expect to eventually have sufficient power from our dataset to examine risk factors for a variety of brain disorders, both individually and in aggregate. Our ultimate goal is to offer scientifically validated ways to preserve and promote brain health by working with our patients' needs and tracking their progress over time.",[85,86,87,88,89,90,91,92,93,94,95,96],"Stroke, Ischemic","Stroke Syndrome","Stroke","Stroke, Acute","Dementia","Brain Ischemia","Brain Diseases","Alzheimer Disease","Health Attitude","Health Knowledge, Attitudes, Practice","Health Personnel Attitude","Healthy Aging",[98,99,100,101,102],"stroke","dementia","Alzheimer disease","Health Brain","Health knowledge","2026-02-21",{"date":105,"type":106},"2026-02-24","ACTUAL",{"date":108,"type":106},"2019-07-01",{"date":110,"type":81},"2048-12-31",{"name":5,"class":6},2]