[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611344":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":18,"locations":29,"responsibleParty":48,"collaborators":18,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":18,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":18,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":74,"overallStatus":82,"whyStopped":18,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Pakistan Association of Cognitive Therapists","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Culturally adapted DBT+Treatment as usual","EXPERIMENTAL","In addition to the usual treatment (TAU), which typically involves pharmacotherapy or supportive counselling from a general physician, participants will receive culturally translated and adapted dialectical behaviour therapy (DBT) materials that fit local cultural and linguistic contexts. Such material will include culturally relevant metaphors, examples, and mindfulness practices. Sessions will be conducted in the form of weekly group skills training (emotion regulation, distress tolerance, interpersonal effectiveness, mindfulness), individual therapy sessions (1 hour\u002Fweek), and telephone coaching as needed.",[13],"Other: Culturally adapted DBT",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment as usual (TAU) only","NO_INTERVENTION","Participants will only receive standard mental health care available in the region (e.g., medication, supportive counselling), usually from a general physician. TAU in Pakistan largely consists of pharmacological treatment with medication and follow-up in an outpatient basis.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"Culturally adapted DBT","Participants will receive culturally translated and adapted dialectical behaviour therapy (DBT) materials that fit local cultural and linguistic contexts. Such material will include culturally relevant metaphors, examples, and mindfulness practices. Sessions will be conducted in the form of weekly group skills training (emotion regulation, distress tolerance, interpersonal effectiveness, mindfulness), individual therapy sessions (1 hour\u002Fweek), and telephone coaching as needed.",[9],[25],{"name":26,"affiliation":27,"role":28},"Mirrat G. Butt, PhD","PACT","PRINCIPAL_INVESTIGATOR",[30],{"facility":5,"status":18,"city":31,"state":32,"zip":18,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Lahore","Punjab Province","Pakistan","PK",{"type":36,"coordinates":37},"Point",[38,39],74.35071,31.558,{"lat":39,"lon":38},[42,47],{"name":43,"role":44,"phone":45,"phoneExt":18,"email":46},"Laiba Qayyum, MSCP","CONTACT","+923021474287","laiba90012@gmail.com",{"name":26,"role":28,"phone":18,"phoneExt":18,"email":18},{"type":49,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100611344","culturally-adapted-dialectical-behavior-therapy-for-low-middle-income-countries-100611344",false,"NCT07239362","CULTURALLY ADAPTED DIALECTICAL BEHAVIOR THERAPY FOR LOW-MIDDLE-INCOME COUNTRIES","Culturally Adapted Dialectical Behavior Therapy (DBT) for Mental Health in LMICs: A Randomized Controlled Trial (RCT)","Inclusion Criteria:\n\n* Adults aged 18-45 years\n* Adults who are diagnosed with or have significant traits of borderline personality disorder (BPD)\n* Adults who are willing to provide written informed consent\n\nExclusion Criteria:\n\n* Severe psychiatric comorbidity (e.g., active psychosis, substance use, etc.)\n* Acute medical conditions interfering with participation\n* Lack of basic reading and writing, or any learning disability","ALL","18 Years","45 Years",{"count":61,"type":62},220,"ESTIMATED","INTERVENTIONAL",[65],"NA","The study aims to assess the efficacy of culturally adapted dialectical behaviour therapy (DBT) for addressing emotional dysregulation in a low- and middle-income country, as well as to evaluate the impact of DBT on secondary outcomes such as borderline personality traits, self-harm or suicide, depression, anxiety, and individuals' functioning and disability.\n\nThrough a rigorous Randomised Controlled Trial (RCT), the research seeks to assess how cultural adaptations of dialectical behaviour therapy improve its applicability, engagement, and outcomes in diverse socio-cultural settings, contributing to more accessible and effective mental health interventions in resource-limited regions.",[68,69,70,71,72,73],"Borderline Personality Disorder (BPD)","Dialectical Behavior Therapy","Emotional Dysregulation","Self Harm","Suicidal and Self-injurious Behavior","Depression Anxiety Disorder",[75,76,77,78,79,80,81],"BPD","DBT","Self harm","Suicide","Borderline personality","Dialectical behavior therapy","Emotional dysregulation","NOT_YET_RECRUITING","2025-11-22",{"date":85,"type":86},"2025-11-28","ACTUAL",{"date":88,"type":62},"2025-11-20",{"date":90,"type":62},"2026-07-31",{"name":5,"class":6},1]