[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523307":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":25,"locations":25,"responsibleParty":26,"collaborators":25,"id":28,"slug":29,"hasResults":30,"nctId":31,"briefTitle":32,"officialTitle":33,"acronym":25,"eligibilityCriteria":34,"healthyVolunteers":30,"sex":35,"minAge":36,"maxAge":37,"enrollmentInfo":38,"targetDuration":25,"studyType":41,"phases":42,"briefSummary":44,"conditions":45,"keywords":25,"overallStatus":47,"whyStopped":25,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":49,"startDateStruct":52,"completionDateStruct":54,"leadSponsor":56,"locationsCount":25},{"fullName":5,"class":6},"Shanghai First Maternity and Infant Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Dual Stimulation Protocol","EXPERIMENTAL","Dual stimulations were performed during the follicular and luteal phases in the same cycle.",[13],"Procedure: duostim vs. two antagonist ovarian stimulations",{"label":15,"type":16,"description":17,"interventionNames":18},"Antagonist Stimulation Protocol","ACTIVE_COMPARATOR","Antagonist stimulations were performed during two consecutive follicular phases in two cycles.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","duostim vs. two antagonist ovarian stimulations","Human menopausal gonadotropin (HMG) 300 IU\u002Fday with flexible antagonist protocol is used for ovarian stimulation, except in luteal phase stimulation of the duostim group. In the duostim group, all of the embryos are frozen. Fresh transfers are performed in the control group, frozen embryo transfers are performed in both control and duostim groups.",[15,9],null,{"type":27,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100523307","cumulative-live-birth-rates-in-dual-ovarian-stimulation-versus-two-antagonist-stimulations-in-poor-ovarian-responders-100523307",false,"NCT06093984","Cumulative Live Birth Rates in Dual Ovarian Stimulation Versus Two Antagonist Stimulations in Poor Ovarian Responders","A Randomized Clinical Trial Comparing Cumulative Live Birth Rates in Dual Ovarian Stimulation Versus Two Antagonist Stimulations in Poor Ovarian Responders","Inclusion Criteria:\n\n* Women with POR were defined with adjusted Bologna criteria, at least two of the three following criteria: advanced maternal age (40 years); 3 oocytes in previous IVF; and antral follicle count (AFC) 5 and\u002For anti-Mu¨llerian hormone (AMH) 1.1 ng\u002Fml (this criterion was mandatory)\n* Aged from 20 to 44 years\n* Body mass index (BMI) from 19 to 32 kg\u002Fm2\n* No more than two previous IVF cycles were recruited\n\nExclusion Criteria:\n\n* Amenorrhoea\n* Follicle stimulating hormone (FSH) 20 IU\u002FL or AFC 1\n* Women with a partner with an extremely severe sperm anomaly or sperm donor use","FEMALE","20 Years","44 Years",{"count":39,"type":40},260,"ESTIMATED","INTERVENTIONAL",[43],"NA","To compare the difference in cumulative live birth rates between dual ovarian stimulation and two antagonist stimulations in poor ovarian responders.",[46],"Infertility","NOT_YET_RECRUITING","2023-10-17",{"date":50,"type":51},"2023-10-23","ACTUAL",{"date":53,"type":40},"2023-11-01",{"date":55,"type":40},"2026-10-30",{"name":5,"class":6}]