[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100479326":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":17,"locations":26,"responsibleParty":49,"collaborators":51,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":60,"eligibilityCriteria":61,"healthyVolunteers":56,"sex":62,"minAge":63,"maxAge":7,"enrollmentInfo":64,"targetDuration":67,"studyType":68,"phases":7,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of Aarhus","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"no intervention, as this is an observational study","no intervention",[13],{"name":14,"affiliation":15,"role":16},"Jens Otto Lunde Jørgensen, Professor","AARHUS UNIVERSITY HOSPITAL, Medical Research Laboratory","STUDY_DIRECTOR",[18,24],{"name":19,"role":20,"phone":21,"phoneExt":22,"email":23},"Simon Bøggild Hansen, MD","CONTACT","41111574","+45","simhan@clin.au.dk",{"name":14,"role":20,"phone":7,"phoneExt":7,"email":25},"joj@clin.au.dk",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Department of Endocrinology and Internal Medicine","RECRUITING","Aarhus","State","8200","Denmark","DK",{"type":36,"coordinates":37},"Point",[38,39],10.21076,56.15674,{"lat":39,"lon":38},[42,44,46],{"name":43,"role":20,"phone":21,"phoneExt":7,"email":23},"Simon B Hansen, MD",{"name":43,"role":45,"phone":7,"phoneExt":7,"email":7},"PRINCIPAL_INVESTIGATOR",{"name":47,"role":48,"phone":7,"phoneExt":7,"email":7},"Jelena Stankovic, MD","SUB_INVESTIGATOR",{"type":50,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[52],{"name":53,"class":6},"Aarhus University Hospital","100479326","cushings-syndrome-before-and-after-treatment-correct-100479326",false,"NCT05521529","Cushing's Syndrome Before and After Treatment (CORRECT)","Effects of CORtisol Excess and REmission in Cushing's Syndrome Over Time (CORRECT): A Prospective Non-interventional Cohort Study","CORRECT","Inclusion Criteria:\n\n* New (≤ 2 months) diagnosis of Cushing's syndrome (CS) of endogenous etiology:\n\n  * ACTH-dependent CS\n  * ACTH-independent CS\n* Age \\>18 years\n* Written informed consent\n\nExclusion Criteria:\n\n* Active cancer\n* Iatrogenic or malignant cause of CS such as adrenocortical carcinoma\n* Chronic heart failure (New York Heart Association class IV)\n* Chronic kidney disease Chronic Kidney Disease stage ≥3 (eGFR \\>30 ml\u002Fmin)\n* Liver disease in the form of cirrhosis\n* Deemed unable to complete the study safely by investigator","ALL","18 Years",{"count":65,"type":66},20,"ESTIMATED","1 Year","OBSERVATIONAL","The purpose of this study is to prospectively study patients with Cushing's syndrome before and after treatment, with a special emphasis on physical function, quality of life, and circadian rhythms.\n\nThe hypotheses are:\n\n* Cushing's syndrome negatively impacts health-related quality of life (HRQoL) and physical functioning\n* Cushing's syndrome is associated with altered circadian rhythms at the whole body level and in peripheral target tissues.\n* These complications partially reverse following disease control.",[71],"Cushing Syndrome",[73,74],"Circadian Rhythm","Quality of Life","2025-04-01",{"date":77,"type":78},"2025-04-04","ACTUAL",{"date":80,"type":78},"2023-02-16",{"date":82,"type":66},"2032-11",{"name":5,"class":6},1]