[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100153261":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":44,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":10,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":56,"minAge":57,"maxAge":10,"enrollmentInfo":58,"targetDuration":10,"studyType":61,"phases":10,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"University of Texas Southwestern Medical Center","OTHER",[8,12,14,17],{"label":9,"type":10,"description":11,"interventionNames":10},"Control group",null,"Normal disease free (non lupus) subjects",{"label":13,"type":10,"description":10,"interventionNames":10},"Diseased Control",{"label":15,"type":10,"description":16,"interventionNames":10},"Diseased group 1","Those subjects with systemic lupus erythematosus.",{"label":18,"type":10,"description":19,"interventionNames":10},"Diseased group 2","Subjects diagnosed with cutaneous lupus.",[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Benjamin Chong, MD, MSCS","CONTACT","214-648-3427","skinlupus.registry@utsouthwestern.edu",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"University of Texas Southwestern Medical Center Dallas","RECRUITING","Dallas","Texas","75390","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-96.80667,32.78306,{"lat":39,"lon":38},[42],{"name":43,"role":23,"phone":24,"phoneExt":10,"email":25},"Benjamin F Chong, MD, MSCS",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ben Chong","Professor","100153261","cutaneous-lupus-registry-100153261",false,"NCT01266915","Cutaneous Lupus Registry","Molecular Studies on Cutaneous Lupus","Inclusion Criteria:\n\n* Diagnosed with cutaneous lupus erythematosus and\u002For systemic lupus erythematosus by clinical, laboratory, and histopathological findings\n* Ability to speak and read English or Spanish at a 6th grade reading level (a translator will be available with additional consent forms in Spanish)\n* Ability to give written informed consent\n\nExclusion Criteria:\n\n* Less than 18 years of age, since the characteristics of the disease in these subjects could be very different\n* Due to a medication, in which its discontinuation results in the resolution of cutaneous lupus, since the characteristics of the disease in these subjects could be very different\n* Medical conditions who do not warrant a skin biopsy\n* Unable to give written, informed consent or undergo a skin biopsy and\u002For venipuncture for any other reason",true,"ALL","18 Years",{"count":59,"type":60},1000,"ESTIMATED","OBSERVATIONAL","Approximately 1.4 million individuals in the United States have systemic lupus erythematosus, and about 85% of these individuals develop skin lesions at some point of their disease. Cutaneous lupus erythematosus represents the skin manifestations of systemic lupus erythematosus, and can appear in people with or without systemic lupus. It is a mentally, physically, and emotionally debilitating disease that affects both the quality of life and social well-being of those affected.\n\nThe cause of cutaneous lupus is not completely understood, but likely includes multiple factors from our genes and the environment. Multiple genetic studies with small numbers of cutaneous lupus patients have been performed to determine which genes are associated with cutaneous lupus. This study aims to accumulate even larger numbers of patients to confidently identify genes and the proteins they encode that could contribute greatly to the formation of cutaneous lupus. The discovery of these genes and proteins would help not only uncover how cutaneous lupus forms, but also improve our abilities to diagnose this disease and predict its course, and stimulate new drug development.",[64],"Lupus Erythematosus",[66,67,68],"SCLE","CLE","DLE","2025-11-20",{"date":71,"type":72},"2025-11-26","ACTUAL",{"date":74,"type":10},"2009-01",{"date":76,"type":60},"2030-12",{"name":5,"class":6},1]