[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642218":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":27,"centralContacts":31,"locations":41,"responsibleParty":56,"collaborators":58,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":11,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":11,"enrollmentInfo":71,"targetDuration":11,"studyType":74,"phases":75,"briefSummary":77,"conditions":78,"keywords":80,"overallStatus":44,"whyStopped":11,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Duke University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Photon counting detector CT myelography (PCD-CTM)","EXPERIMENTAL",null,[13],"Diagnostic Test: photon counting detector CT myelography (PCD- CTM)",{"label":15,"type":6,"description":11,"interventionNames":16},"Energy integrating detector CT myelography (EID-CTM)",[17],"Diagnostic Test: energy integrating detector CT myelography (EID-CTM)",[19,24],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"DIAGNOSTIC_TEST","photon counting detector CT myelography (PCD- CTM)","Randomization (1:1) to either photon counting detector CT myelography (PCD- CTM) or energy integrating detector CT myelography (EID-CTM)",[9],{"type":20,"name":25,"description":22,"armGroupLabels":26,"otherNames":11},"energy integrating detector CT myelography (EID-CTM)",[15],[28],{"name":29,"affiliation":5,"role":30},"Timothy J Amrhein, MD","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":11,"email":36},"Primary Clinical Research Coordinator","CONTACT","919-684-7810","latonia.strader@duke.edu",{"name":38,"role":34,"phone":39,"phoneExt":11,"email":40},"Clinical Research Specialist","919-684-3296","amy.cuddington@duke.edu",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":11},"Duke University Medical Center","RECRUITING","Durham","North Carolina","27710","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-78.89862,35.99403,{"lat":54,"lon":53},{"type":57,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[59],{"name":60,"class":61},"Siemens Healthineers","UNKNOWN","100642218","cvfs-in-sih-eid-vs-pcd-ctm-100642218",false,"NCT07582744","CVFs in SIH: EID vs. PCD CTM","CSF-Venous Fistula Detection in Spontaneous Intracranial Hypotension: Comparative Diagnostic Yields of Energy Integrating Detector Versus Photon Counting Detector CT Myelography","Inclusion Criteria:\n\n1. Adult patient,\n2. Confirmed diagnosis of SIH using International Classification of Headache Disorders criteria (third edition), and\n3. Brain MRI demonstrating at least one positive imaging finding for SIH (e.g., dural enhancement, venous sinus distention, brain sagging, pituitary engorgement, spontaneous subdural fluid collections).\n\nExclusion Criteria:\n\n1. Prior treatment of a CVF,\n2. Inability to undergo both exams (EID-CTM and PCD-CTM) if needed for diagnosis,\n3. Spine MRI demonstrating extradural CSF (confirming CSF leak type other than CVF), and\n4. inability to provide informed consent.","ALL","18 Years",{"count":72,"type":73},200,"ESTIMATED","INTERVENTIONAL",[76],"NA","The purpose of this research study is to compare two types of Computed Tomography Myelography (CTM) scans, one on the photon counting detector scanner (called PCD-CTM) and the other on the energy integrating detector scanner (called EID-CTM); both of which doctors usually use to diagnose abnormal connections between the cerebrospinal fluid and the venous system, or CSF-venous fistulas. This study will help to see if the newer PCD-CTM scan can find more spinal fluid leaks \\[CSF-venous fistulas (CVF)\\] than the scan that is normally used (EID-CTM).",[79],"Spontaneous Intracranial Hypotension",[81,82,83],"CSF-venous fistula","Photon counting detector CT myelography","Energy integrating detector myelography","2026-06-11",{"date":86,"type":87},"2026-06-15","ACTUAL",{"date":89,"type":87},"2026-05-21",{"date":91,"type":73},"2028-08",{"name":5,"class":6},1]