[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639546":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":38,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":10,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":10,"enrollmentInfo":51,"targetDuration":10,"studyType":54,"phases":10,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Sohag University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Mechanically Ventilated COPD Patients",null,"COPD patients receiving invasive mechanical ventilation who fulfill weaning readiness criteria and undergo spontaneous breathing trial with assessment of D-RSBI and conventional RSBI.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Ahmed Atef Mohamed, MBBCh","CONTACT","+201006973892","ahmed_ateff_post@med.sohag.edu.eg",[19],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Sohag University Hospital","RECRUITING","Sohag","Sohag Governorate","82524","Egypt","EG",{"type":28,"coordinates":29},"Point",[30,31],31.69478,26.55695,{"lat":31,"lon":30},[34],{"name":35,"role":15,"phone":36,"phoneExt":10,"email":37},"Ahmed Atef Mohamed Sayed, MBBCh","+2001006973892","atef53370@gmail.com",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Ahmed Atef Mohamed","Resident of Anesthesia, ICU and Pain Management faculty of medicine Sohag University","100639546","d-rsbi-versus-rsbi-for-predicting-weaning-success-in-copd-patients-100639546",false,"NCT07590362","D-RSBI Versus RSBI for Predicting Weaning Success in COPD Patients","Diaphragmatic Rapid Shallow Breathing Index (D-RSBI) Versus Traditional Rapid Shallow Breathing Index (RSBI) for Prediction of Weaning Success From Mechanical Ventilation in COPD Patients","Inclusion Criteria:\n\n* Mechanically ventilated COPD patients fulfilling standard weaning readiness criteria.\n* Invasive mechanical ventilation for more than 24 hours before spontaneous breathing trial.\n* Hemodynamically stable without significant vasopressor support.\n* Adequate oxygenation with FiO2 ≤ 0.5 and PEEP ≤ 8 cmH2O .\n* Preserved mental status and ability to initiate spontaneous breathing.\n* Successful tolerance of spontaneous breathing trial conducted on CPAP mode with pressure support ≤ 8 cmH2O.\n\nExclusion Criteria:\n\n* Refusal of consent\n* Neuromuscular disease, phrenic nerve palsy, or diaphragmatic paralysis.\n* Large pneumothorax or pathology interfering with ultrasound assessment.\n* Terminal extubation.\n* Recent major thoracic surgery.\n* Poor sonographic window despite repeated attempts.","ALL","18 Years",{"count":52,"type":53},100,"ESTIMATED","OBSERVATIONAL","This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success from invasive mechanical ventilation in COPD patients. Diaphragmatic ultrasound measurements will be performed during spontaneous breathing trials, and patients will be followed for 72 hours after extubation to assess weaning outcomes.",[57,58],"Chronic Obstructive Pulmonary Disease (COPD)","Mechanical Ventilator Weaning",[60,61,62,63,64],"D-RSBI","RSBI","COPD","Diaphragm Ultrasound","Mechanical Ventilation Weaning","2026-05-14",{"date":67,"type":68},"2026-05-15","ACTUAL",{"date":70,"type":68},"2026-04-15",{"date":72,"type":53},"2027-06",{"name":5,"class":6},1]