[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601827":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":60,"collaborators":64,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":24,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":24,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":36,"whyStopped":24,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Connecticut","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","PLACEBO_COMPARATOR","The inert amino acid (alanine) will serve as an isonitrogenous control.",[13],"Dietary Supplement: Control (placebo)",{"label":15,"type":16,"description":17,"interventionNames":18},"Targeted Amino Acid Supplement","EXPERIMENTAL","Blend of the essential amino acids (Leucine \\& Tryptophan), a conditionally essential amino acids (Arginine \\& Taurine), and non-essential amino acids (Glutamate \\& Tyrosine) designed to meet the unique nutritional needs of people with Parkinson's disease (PD).",[19],"Dietary Supplement: Targeted Amino Acid Supplement",[21,25],{"type":22,"name":15,"description":17,"armGroupLabels":23,"otherNames":24},"DIETARY_SUPPLEMENT",[15],null,{"type":22,"name":26,"description":11,"armGroupLabels":27,"otherNames":24},"Control (placebo)",[9],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Carlos Rehbein, MS","CONTACT","860-486-1121","carlos.rehbein@uconn.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Storrs","Connecticut","06269","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-72.24952,41.80843,{"lat":46,"lon":45},[49,53,55,58],{"name":50,"role":31,"phone":51,"phoneExt":24,"email":52},"Jacob Earp, MS","860-486-2671","jacob.earp@uconn.edu",{"name":54,"role":31,"phone":24,"phoneExt":24,"email":33},"Carlos Rehbein",{"name":56,"role":57,"phone":24,"phoneExt":24,"email":24},"Jacob Earp, PhD","PRINCIPAL_INVESTIGATOR",{"name":59,"role":57,"phone":24,"phoneExt":24,"email":24},"Cristina Colon-Semenza, PT, MPT, PhD",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"SPONSOR_INVESTIGATOR","Cristina Colon-Semenza","Assistant Professor",[65],{"name":66,"class":67},"United States Department of Agriculture (USDA)","FED","100601827","daily-amino-acid-supplementation-for-people-with-parkinsons-disease-100601827",false,"NCT07115563","Daily Amino Acid Supplementation for People With Parkinson's Disease","Effects of Targeted Amino Acid Supplementation for People With Parkinson's Disease on Amino Acid Profiles and Health Related Markers","Inclusionary Criteria:\n\n* Male and Females.\n* 50-80 Years.\n* Previous diagnosis of idiopathic Parkinson's Disease by patient report.\n* Use of dopamine replacement medication (e.g. levodopa) for at least 2 years.\n* On a stable dose of dopamine replacement medication for at least 3 months with no plans for change in the next two months.\n\nExclusionary criteria\n\n* Apparent cognitive impairment as determined by phone screening (Telephone Interview for Cognitive Status \\\u003C29).\n* Diagnosis of Parkinsonism or atypical Parkinson's Disease.\n* Prescription of Dopamine antagonist.\n* Any unstable medical condition.\n* Use of Deep Brain Stimulation.\n* Gastric or Bowel resection surgery.\n* Contraindications to blood draw.","ALL","50 Years","80 Years",{"count":79,"type":80},30,"ESTIMATED","INTERVENTIONAL",[83],"NA","The goal of this clinical trial is to learn if a tailored amino acid supplement works to help adults living with Parkinson's disease to improve nutrition, metabolic function, body composition, and physical and mental function. The main questions it aims to answer are:\n\nDoes the tailored amino acid supplement increase essential amino acids (nutritional status)?\n\nDoes the tailored amino acid supplement increase an antioxidant (complex amino acid) and decrease an amino acid associated with oxidative stress?\n\nDoes the tailored amino acid supplement improve physical and mental health compared to a placebo supplement?\n\nResearchers will compare the tailored amino acid supplement to a placebo (a look-alike substance that contains no active ingredients) to see if the tailored amino acid supplements work to support health for people with Parkinson's disease.\n\nParticipants will:\n\nTake the tailored amino acid supplement or a placebo every day for 6 months, visit the lab at baseline, after 3 months, and after 6 months for fasting blood draws, body composition assessment, and physical and mental health testing and keep a diary of their food intake and supplement intake.",[86],"Parkinson Disease (PD)",[88,89,90],"Nutrition","Parkinson's disease","Amino acid supplements","2026-06-30",{"date":93,"type":94},"2026-07-02","ACTUAL",{"date":96,"type":94},"2025-10-31",{"date":98,"type":80},"2027-11",{"name":62,"class":6},1]